WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m6A-dependent manner

Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma

(2020) Qian Zhu et al.   Journal of Hematology & Oncology

The N 6 -Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy

(2019) Lisa E. Dorn et al.   CIRCULATION

The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network

(2019) Maosheng Cheng et al.   ONCOGENE

HACE1 is a potential tumor suppressor in osteosarcoma

(2019) Amal M El-Naggar et al.   Cell Death & Disease

Osteosarcoma cell intrinsic PD-L2 signals promote invasion and metastasis via the RhoA-ROCK-LIMK2 and autophagy pathways

(2019) Tingting Ren et al.   Cell Death & Disease

Physiological functions of Wilms’ tumor 1-associating protein and its role in tumourigenesis

(2019) Wenli Xie et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia

(2019) Jasmin Paris et al.   Cell Stem Cell

High expression of HMBOX1 contributes to poor prognosis of gastric cancer by promoting cell proliferation and migration

(2019) Nannan Diao et al.   BIOMEDICINE & PHARMACOTHERAPY

m6A enhances the phase separation potential of mRNA

(2019) Ryan J. Ries et al.   NATURE

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112

(2019) Nhan van Tran et al.   NUCLEIC ACIDS RESEARCH

WTAP is a prognostic marker of high-grade serous ovarian cancer and regulates the progression of ovarian cancer cells

(2019) Hai-Lan Yu et al.   OncoTargets and Therapy

METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance

(2019) Qiang Wang et al.   GUT

m6A RNA Methylation Regulators Contribute to Malignant Progression and Have Clinical Prognostic Impact in Gastric Cancer

(2019) Yunshu Su et al.   Frontiers in Oncology

MUC13 promotes intrahepatic cholangiocarcinoma progression via EGFR/PI3K/AKT pathways

(2019) Pei Tiemin et al.   JOURNAL OF HEPATOLOGY

Low expression level of HMBOX1 in high-grade serous ovarian cancer accelerates cell proliferation by inhibiting cell apoptosis

(2018) Yun-Liang Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-19a-mediated downregulation of RhoB inhibits the dephosphorylation of AKT1 and induces osteosarcoma cell metastasis

(2018) Qingping Zou et al.   CANCER LETTERS

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d

(2018) Philip Knuckles et al.   GENES & DEVELOPMENT

Zc3h13 Regulates Nuclear RNA m 6 A Methylation and Mouse Embryonic Stem Cell Self-Renewal

(2018) Jing Wen et al.   MOLECULAR CELL

Deep RNA sequencing reveals the dynamic regulation of miRNA, lncRNAs, and mRNAs in osteosarcoma tumorigenesis and pulmonary metastasis

(2018) Lin Xie et al.   Cell Death & Disease

Wilms’ tumor 1-associating protein plays an aggressive role in diffuse large B-cell lymphoma and forms a complex with BCL6 via Hsp90

(2018) Yue Kuai et al.   Cell Communication and Signaling

Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion

(2018) Zhenrui Li et al.   CELL RESEARCH

Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development

(2018) Mateusz Mendel et al.   MOLECULAR CELL

The Role of m6A/m-RNA Methylation in Stress Response Regulation

(2018) Mareen Engel et al.   NEURON

METTL3 regulates WTAP protein homeostasis

(2018) Melissa Sorci et al.   Cell Death & Disease

Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism

(2018) Huensuk Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biology of m6A RNA Methylation in Normal and Malignant Hematopoiesis

(2018) Ly P. Vu et al.   Cancer Discovery

Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression

(2018) Subbarayalu Panneerdoss et al.   Science Advances

Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening

(2017) Shuliang Zhou et al.   ONCOLOGY REPORTS

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Carbonic anhydrase IVinhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP–WT1–TBL1 axis

(2015) Jingwan Zhang et al.   GUT

WTAP is a novel oncogenic protein in acute myeloid leukemia

(2014) H Bansal et al.   LEUKEMIA

RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

(2013) Jean-Michel Fustin et al.   CELL

Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle

(2013) Keiko Horiuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WTAP regulates migration and invasion of cholangiocarcinoma cells

(2013) Hong-Jae Jo et al.   JOURNAL OF GASTROENTEROLOGY

HMBOX1 negatively regulates NK cell functions by suppressing the NKG2D/DAP10 signaling pathway

(2011) Longyan Wu et al.   Cellular & Molecular Immunology

HMBOX1, homeobox transcription factor, negatively regulates interferon-γ production in natural killer cells

(2011) Longyan Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Role of Hmbox1 in Endothelial Differentiation of Bone-Marrow Stromal Cells by a Small Molecule

(2010) Le Su et al.   ACS Chemical Biology