Integrative Analysis of the IQ Motif-Containing GTPase-Activating Protein Family Indicates That the IQGAP3-PIK3C2B Axis Promotes Invasion in Colon Cancer

AJCC 8th Edition: Colorectal Cancer

(2018) Martin R. Weiser   ANNALS OF SURGICAL ONCOLOGY

Over-expression of IQGAP1 indicates poor prognosis in head and neck squamous cell carcinoma

(2018) Cong-Cong Wu et al.   JOURNAL OF MOLECULAR HISTOLOGY

Overexpression of IQGAP1 promotes the angiogenesis of esophageal squamous cell carcinoma through the AKT and ERK‑mediated VEGF‑VEGFR2 signaling pathway

(2018) Chao‑Hui Li et al.   ONCOLOGY REPORTS

Downregulation of IQGAP2 Correlates with Prostate Cancer Recurrence and Metastasis

(2018) Yanyun Xie et al.   Translational Oncology

LGR5 receptor promotes cell–cell adhesion in stem cells and colon cancer cells via the IQGAP1–Rac1 pathway

(2017) Kendra S. Carmon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2

(2017) A. Jane Bardwell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

IQGAP1 is an oncogenic target in canine melanoma

(2017) Becky H. Lee et al.   PLoS One

Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis

(2017) Marcus Kind et al.   PLoS One

A novel mechanism of ERK1/2 regulation in smooth muscle involving acetylation of the ERK1/2 scaffold IQGAP1

(2017) Susanne Vetterkind et al.   Scientific Reports

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression

(2016) Anissa Chikh et al.   Oncotarget

Novel roles for class II Phosphoinositide 3-Kinase C2β in signalling pathways involved in prostate cancer cell invasion

(2016) Ioanna Mavrommati et al.   Scientific Reports

Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms

(2015) Laura Novellasdemunt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The biology of IQGAP proteins: beyond the cytoskeleton

(2015) A. C. Hedman et al.   EMBO REPORTS

Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity

(2015) Samira Alliouachene et al.   Cell Reports

Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis

(2014) Makoto Adachi et al.   GENES TO CELLS

IQGAP3 Promotes EGFR-ERK Signaling and the Growth and Metastasis of Lung Cancer Cells

(2014) Ying Yang et al.   PLoS One

IQGAP1 Mediates Angiotensin II-Induced Apoptosis of Podocytes via the ERK1/2 MAPK Signaling Pathway

(2013) Yipeng Liu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Overexpression of IQGAP1 in human pancreatic cancer

(2013) Xiao-Xia Wang et al.   Hepatobiliary & Pancreatic Diseases International

Phosphatidylinositol 3-Kinase-C2β Inhibits Cisplatin-Mediated Apoptosis via the Akt Pathway in Oesophageal Squamous Cell Carcinoma

(2013) Z Liu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors

(2013) Katherine L Jameson et al.   NATURE MEDICINE

IQGAP1 Functions as a Modulator of Dishevelled Nuclear Localization in Wnt Signaling

(2013) Toshiyasu Goto et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

IQGAP2, A candidate tumour suppressor of prostate tumorigenesis

(2012) Yanyun Xie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing

(2012) Pengyuan Liu et al.   CARCINOGENESIS

Cooperative Activation of PI3K by Ras and Rho Family Small GTPases

(2012) Hee Won Yang et al.   MOLECULAR CELL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma

(2010) Colin D White et al.   BMC GASTROENTEROLOGY

A ‘metastasis-prone’ signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics

(2010) Yi Hong et al.   CLINICAL & EXPERIMENTAL METASTASIS

IQGAP1 Plays an Important Role in the Invasiveness of Thyroid Cancer

(2010) Z. Liu et al.   CLINICAL CANCER RESEARCH

Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas

(2010) Jochen Gaedcke et al.   GENES CHROMOSOMES & CANCER

Correction: Modeling Oncogenic Signaling in Colon Tumors by Multidirectional Analyses of Microarray Data Directed for Maximization of Analytical Reliability

(2010) Magdalena Skrzypczak et al.   PLoS One

Peroxisome proliferator-activated receptor γ and colorectal cancer

(2010) Yun Dai   World Journal of Gastrointestinal Oncology

Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells

(2009) Beatrix Hage et al.   Cell Communication and Signaling

A survey of glioblastoma genomic amplifications and deletions

(2009) Shailaja K. Rao et al.   JOURNAL OF NEURO-ONCOLOGY

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Development of Hepatocellular Carcinoma in Iqgap2-Deficient Mice Is IQGAP1 Dependent

(2008) V. A. Schmidt et al.   MOLECULAR AND CELLULAR BIOLOGY

IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade

(2008) Hisashi Nojima et al.   NATURE CELL BIOLOGY