Article
Chemistry, Analytical
Dusan Losic, Farzaneh Farivar, Pei Lay Yap, Afshin Karami
Summary: Counterfeits in the supply chain of high-value advanced materials like graphene have become a concern, with recent studies showing a large percentage of manufactured graphene materials not actually being graphene. Traditional characterization methods have limitations, making it crucial to use reliable methods like thermogravimetric analysis (TGA) to detect unwanted additives. Research demonstrates the superior performance of TGA in successfully identifying carbon additives mixed with graphene materials.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Yuetong Yang, Derong Kong, Yungen Wu, Yiheng Chen, Changhao Dai, Chang Chen, Junhong Zhao, Shi Luo, Wentao Liu, Yunqi Liu, Dacheng Wei
Summary: A graphene field-effect transistor (GFET) biosensor based on a tetrahedral DNA nanostructure (TDN)-assisted catalytic hairpin assembly (CHA) reaction (TCHA) has been developed, allowing sensitive and specific detection of miRNA-21. The TDN structures in the biosensing interface facilitate the CHA reaction and prevent unwanted entanglements, aggregation, and adsorption of probes on the graphene channel. The biosensor exhibits ultra-sensitive detection of miRNA-21, with a detection limit of 5.67 x 10(-19) M, three orders of magnitude lower than that achieved by graphene transistors with single-stranded DNA probe functionalization of the channel. Furthermore, the biosensor demonstrates excellent performance in terms of selectivity, stability, and reproducibility, showing promising potential in bioanalysis and clinical diagnosis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yuetong Yang, Derong Kong, Yungen Wu, Yiheng Chen, Changhao Dai, Chang Chen, Junhong Zhao, Shi Luo, Wentao Liu, Yunqi Liu, Dacheng Wei
Summary: Graphene field-effect transistors (GFETs) offer simple and label-free diagnostics for sensitive and specific detection of microRNAs (miRNAs). Researchers have developed a GFET biosensor based on tetrahedral DNA nanostructures (TDN) that facilitates catalytic hairpin assembly (CHA) reaction for ultrasensitive detection of miRNA-21. The biosensor exhibits excellent analytical performance and has been successfully applied in complex serum environments and cell lysates, showing promising potential in bioanalysis and clinical diagnosis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Soha Aldroubi, Eric Anglaret, Ibrahim Bou Malham, Peter Hesemann, Nicolas Brun, Ahmad Mehdi
Summary: The use of aromatic imidazolium-based ionic liquids has been demonstrated as an effective method for the sonochemical exfoliation of graphite, resulting in stable graphene dispersions. Specifically, 1-(naphthylmethyl)-3-benzylimidazolium bis(trifluoromethanesulfonyl)imide was found to produce solid dispersions of few layer graphene sheets with long-term stability and high concentration at room temperature.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Kai Ling Ng, Barbara M. Maciejewska, Ling Qin, Colin Johnston, Jesus Barrio, Maria -Magdalena Titirici, Iakovos Tzanakis, Dmitry G. Eskin, Kyriakos Porfyrakis, Jiawei Mi, Nicole Grobert
Summary: Achieving sustainable and low-cost production of high-quality graphene is a challenge for large-scale utilization of 2D materials. This study demonstrates that isopropanol can exfoliate graphite as efficiently as NMP, providing potential for sustainable graphene manufacturing.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Jason Stafford, Nwachukwu Uzo, Usmaan Farooq, Silvia Favero, Si Wang, Hsueh-Hung Chen, Anouk L'Hermitte, Camille Petit, Omar K. Matar
Summary: Shear-assisted liquid exfoliation is a promising method for producing defect-free 2D materials. Different methods for delaminating nanosheets from layered precursors in solution have emerged, leading to variability in performance and material quality. By studying the shear exfoliation mechanism and deriving key hydrodynamic parameters, real-time measurement of concentration profiles, and rapid optimization of green solvent design, high-throughput material production can be achieved.
Article
Chemistry, Physical
Jing Zhang, Yi Yang, Xiaohui Huang, Qian Shan, Wei Wu
Summary: This paper efficiently prepared high-yield graphene and visible light-driven photocatalyst graphene/ZnO composite by combining ball-milling and liquid-phase exfoliation under mild conditions. The unique features of this approach include the increased yield of graphene, convenient obtaining of GR/ZnO composite, and easy removal of ZnO-PVA particles from the graphene solution.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Engineering, Environmental
Andrew J. Sellathurai, Sreemannarayana Mypati, Marianna Kontopoulou, Dominik P. J. Barz
Summary: This study successfully achieved the preparation of highly concentrated graphene nanoplatelet dispersions by using graphene oxide as a dispersing agent in the liquid phase exfoliation process. The factors affecting the exfoliation process, such as the concentration of graphene oxide, size of graphite sheets, viscosity of the dispersion, etc., were investigated. Additionally, the exfoliated graphene dispersions were used to synthesize graphene hydrogel electrode materials, demonstrating good capacitance performance and cycling stability.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Wenguang Yu, Xuefeng Gao, Zhicheng Yuan, Haihui Liu, Xuechen Wang, Xingxiang Zhang
Summary: This study presents an environmentally friendly and efficient method for fabricating functionalized graphene using ball milling and an in situ reaction. The researchers found that graphene can act as an electron donor or attractor, and functionalized graphene exhibits a high electrical conductivity. The application of functionalized graphene also improves the tensile strength and Young's modulus of polymer composite fibers.
Article
Engineering, Mechanical
Zeyong Han, Chaoliang Gan, Xiaopeng Li, Peng Feng, Xiaoliang Ma, Xiaoqiang Fan, Minhao Zhu
Summary: In this study, imidazolyl dinitrile amine salt was used as an intercalation agent and modifier to achieve the exfoliation and modification of graphite into graphene. Surface/interface techniques were employed to ensure successful preparation and high-density modification of the graphene. The modified graphene showed improved tribological behaviors and stability in polyethylene glycol 200, attributed to its thinner size and protective layer on mating interfaces.
TRIBOLOGY INTERNATIONAL
(2021)
Article
Chemistry, Physical
Cristian Vacacela Gomez, Marco Guevara, Talia Tene, Luis Villamagua, Gabriela Tubon Usca, Frank Maldonado, Carlos Tapia, Antonino Cataldo, Stefano Bellucci, Lorenzo S. Caputi
Summary: This study presents the liquid exfoliation process of graphene, investigating the effects of various technical parameters and exploring the possibility of optimizing the short-time exfoliation process. By combining experimental and theoretical approaches, it reveals the exfoliation efficiency of graphene in different solvents and analyzes the underlying reasons.
APPLIED SURFACE SCIENCE
(2021)
Article
Crystallography
Nasima Akter, Muhammad Taqiyuddin Mawardi Ayob, Shahidan Radiman, Mayeen Uddin Khandaker, Hamid Osman, Sultan Alamri
Summary: This study demonstrates a cost-effective technique of bio-surfactant-assisted liquid-phase exfoliation of few-layer graphene with low defect ratio. State-of-the-art characterization techniques were employed to confirm the presence of graphene, showing typical Tyndall scattering. The use of a biocompatible surfactant facilitated exfoliation at a low critical micelle concentration, producing large-surface-area graphene for various applications.
Article
Chemistry, Multidisciplinary
Yu Lin, Defang Ding, Chunyan Hu, Zhen Li, Yi Shen, Fan Xia
Summary: The study reveals the microstructural differences between graphene oxide (GO) products made from different flake graphites, which significantly affect the performance of GO. It also highlights the importance of precise selection of graphite in the preparation of GO.
Article
Nanoscience & Nanotechnology
Stevan Andric, Tijana Tomasevic-Ilic, Marko Boskovic, Milija Sarajlic, Dana Vasiljevic-Radovic, Milce M. Smiljanic, Marko Spasenovic
Summary: This work presents chemiresistive graphene-based humidity sensors that exhibit unique performance parameters, including resistance changes up to 10% with different humidity levels, linear response over a wide range of relative humidity levels (8% to 95%), weak sensitivity to other air constituents, flexibility, transparency of approximately 80%, and a fast response time of 30 ms. These sensors are suitable for applications in respiration monitoring and real-time finger proximity detection, particularly in flexible touchless interactive panels.
Article
Chemistry, Analytical
Fenghui Qi, Yuelan He, Yanian Xiong, Jianzhong Lu, Yuhao Zhang
Summary: A simple and sensitive turn-off biosensor for miRNA-21 detection based on tyramine signal amplification (TSA) was developed, which can achieve high sensitivity detection of low concentration miRNA. The method has great potential for disease diagnosis, as demonstrated in human lung cancer cells.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Vahid Nasirian, Mojtaba Shamsipur, Fatemeh Molaabasi, Kamran Mansouri, Morteza Sarparast, Vonny Salim, Ali Barati, Soheila Kashanian
SENSORS AND ACTUATORS B-CHEMICAL
(2020)
Review
Chemistry, Multidisciplinary
Hamid Cheraghian Radi, Behnam Hajipour-Verdom, Fatemeh Molaabasi
Summary: This review provides an overview of the history and development of macromolecular crystallization, including various parameters influencing the crystallization process and different methods available. In addition, novel approaches and the application of automation technology in macromolecular crystallization are discussed.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Analytical
Elham Emami, Mohammad H. Mousazadeh
Summary: Novel zwitterionic carbon dots with good fluorescence properties were successfully synthesized in this study, showing high selectivity and sensitivity for detecting rituximab, along with low toxicity and good stability.
Article
Chemistry, Physical
Elham Emami, Mohammad H. Mousazadeh
Summary: In this study, spirulina algae were utilized for synthesizing green fluorescent-carbon dots (G-CDs) and a fluorescent probe based on G-CDs was successfully designed for detection of Cu2+ and C2O42-, showing potential applications in tap water, mineral water, and living cells.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Environmental Sciences
H. Jaberi, E. Emami, M. H. Mousazadeh
Summary: The pollution of water sources by industrial dyes is a global concern, and this study demonstrates the successful synthesis of carbon dots from l-histidine amino acid and citric acid for use as an effective adsorbent to remove Methlyene Blue dye. The removal efficiency reaches 97.0%, indicating the promising potential of CDs/HMS as an adsorbent for cationic dye removal.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Physical
Nazanin Hashemi, Mohammad H. Mousazadeh
Summary: The development of green methods for carbon dots synthesis from natural precursors, such as Red Beetroot, via a low-cost, simple, and green hydrothermal treatment has gained significant attention. The synthesized CDs exhibited excellent performance, especially in the detection of Pd2+ ions, and showed potential as biocompatible labels for cellular imaging.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Zahra Gharehdaghi, Rahmatollah Rahimi, Seyed Morteza Naghib, Fatemeh Molaabasi
Summary: In this study, two types of Cu-MOF-based nanocomposites, GO/Cu-TCPP and Fe3O4@Cu-3(BTC)(2), were investigated for loading and pH-sensitive release of doxorubicin (DOX). It was found that GO/Cu-TCPP had a higher adsorption capacity for DOX compared to Fe3O4@Cu-3(BTC)(2). The release of DOX from both nanocomposites was pH-sensitive, with GO/Cu-TCPP releasing a higher percentage of DOX at pH 5 than at pH 7.4. The difference in drug release between the two nanocomposites was attributed to their differences in drug loading capacity. The results indicate that both GO/Cu-TCPP and Fe3O4@Cu-3(BTC)(2) nanocomposites have low toxicity and good biocompatibility.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2022)
Article
Materials Science, Multidisciplinary
Nazanin Hashemi, Mohammad H. Mousazadeh
Summary: In this study, water-soluble nitrogen-doped carbon dots (N-CDs) based fluorescent probes were successfully synthesized with small size distribution and high quantum yield. These probes showed selective quenching of Fe3+ ions and exhibited high stability and reliability in detecting Fe3+ ions, making them suitable for environmental applications.
Article
Nanoscience & Nanotechnology
Maryam Hosseini, Zahed Ahmadi, Amirhosein Kefayat, Fatemeh Molaabasi, Anita Ebrahimpour, Yousef Naderi Khojasteh Far, Mehdi Khoobi
Summary: In this study, a helical structure of gold nanoparticles was engineered using Spirulina platensis as a biotemplate for the treatment and diagnosis of cancer. The biohybrid showed excellent imaging performance and tumor suppression effects, as well as biodegradability and good biocompatibility.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Fatemeh Molaabasi, Amirhosein Kefayat, Abbas Ghasemzadeh, Mojdeh Amandadi, Mojtaba Shamsipur, Mozhgan Alipour, Seyyed Ebrahim Moosavifard, Maryam Besharati, Saman Hosseinkhani, Ramin Sarrami-Forooshani
Summary: A label-, antibody-, enzyme-, and amplification-free ratiometric fluorescent biosensor has been developed for the rapid and low-cost diagnosis of COVID-19. The biosensor exhibits high sensitivity and specificity, and can detect the virus using isolated RNA samples.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Elham Emami, Mohammad H. Mousazadeh
Summary: In this study, nitrogen-doped carbon dots (N-CDs) fluorescent probes were conveniently synthesized using spirulina algae and L-arginine through a one-pot hydrothermal treatment. The N-CDs exhibited excellent stability, exceptional optical performance, superior biocompatibility, and low cytotoxicity. They can be used as a "turn-off" response for Fe3+ detection, with a detection limit of 14.8 nM and a linear response in the range of 0.05-1 μM. The fluorescence quenching mechanism of N-CDs was proposed to be due to the easy combination of Fe3+ with functional groups on the surface of N-CDs and induced aggregation. The N-CDs nanosensor also showed the ability to detect L-alanine and L-histidine, with detection limits as low as 52.8 nM and 69 nM, respectively, in a good linear relationship in the range of 0.5-50 μM.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Nanoscience & Nanotechnology
Mojtaba Shamsipur, Elaheh Babaee, Mohammad-Bagher Gholivand, Fatemeh Molaabasi, Farimah Mousavi, Ali Barati, Behnam Hajipour Verdom, Behnaz Shojaedin-Givi, Hossein Naderi-Manesh
Summary: In this study, a new fluorescence probe based on insulin-capped gold nanoclusters (Ins/Au-NCs) was developed for selective detection of Cu2+ ions and glutathione (GSH). The probe showed high sensitivity and stability. Cu2+ ions caused fluorescence quenching of Ins/Au-NCs, which could be recovered in the presence of GSH. The probe had low detection limits and broad linear ranges for Cu2+ ions and GSH. It also showed promising application in detecting low levels of Cu2+ ions and GSH in water and human serum samples.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
N. Jamali, N. Ramezani, M. H. Mousazadeh
Summary: This study synthesized two V/W-HMS compounds with varying vanadium and tungsten loadings, and found that the optimal catalyst exhibited high catalytic activity in oxidative desulfurization of DBT in model diesel fuel. The doping of vanadium and tungsten lowered the bandgap of the catalyst, leading to improved catalytic performance, even after repeated use. The research also investigated the reaction kinetics, mechanisms, and bandgap energies of the catalysts.
PHYSICAL CHEMISTRY RESEARCH
(2021)
Article
Multidisciplinary Sciences
Termeh Teymoorian, Nazanin Hashemi, Mohammad H. Mousazadeh, Zahra Entezarian
Summary: This study developed nitrogen and sulfur-doped carbon quantum dots loaded inside hexagonal mesoporous silica for efficient removal of methylene blue dye from aqueous solutions. The adsorption parameters were investigated to determine the maximum adsorption capacity and removal efficiency under optimal conditions. The prepared adsorbent showed excellent selective behavior for methylene blue absorption and could be well recycled after repeated cycles.
SN APPLIED SCIENCES
(2021)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
