期刊
SCIENCE OF THE TOTAL ENVIRONMENT
卷 735, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.scitotenv.2020.139275
关键词
Antibiotic-resistant genes; Naked DNA; Resurrection of microbes; Antarctica; Permafrost; Global change
资金
- second Tibetan Plateau Scientific Expedition and Research Program (STEP) [2019QZKK0605]
- Strategic Priority Research Programme of the Chinese Academy of Sciences, Pan-Third Pole Environment Study for a Green Silk Road (Pan-TPE) [XDA20040501]
- National Natural Science Foundation of China [41630754]
- PIFI Fellowship from the Chinese Academy of Sciences [2020PC0052]
The present world faces a new threat of ancient microbes and resistomes that are locked in the cryosphere and now releasing upon thawing due to climate change and anthropogenic activities. The cryosphere act as the best preserving place for these microbes and resistomes that stay alive for millions of years. Current reviews extensively discussed whether the resurrection of microbes and resistomes existing in these pristine environments is true or just a hype. Release of these ancient microorganisms and naked DNA is of great concern for society as these microbes can either cause infections directly or they can interact with contemporary microorganisms and affect their fitness, survival, and mutation rate. Moreover, the contemporary microorganisms may uptake the unlocked naked DNA, which might transform non-pathogenic microorganisms into deadly antibiotic-resistant microbes. Additionally, the resurrection of glacial microorganisms can cause adverse effects on ecosystems downstream. The release of glacial pathogens and naked DNA is real and can lead to fatal outbreaks; therefore, we must prepare ourselves for the possible reemergence of diseases caused by these microbes. This study provides a scientific base for the adoption of actions by international cooperation to develop preventive measures.
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