Species-specific segmentation clock periods are due to differential biochemical reaction speeds

In vitro characterization of the human segmentation clock

(2020) Margarete Diaz-Cuadros et al.   NATURE

Recapitulating the human segmentation clock with pluripotent stem cells

(2020) Mitsuhiro Matsuda et al.   NATURE

Species-specific pace of development is associated with differences in protein stability

(2020) Teresa Rayon et al.   SCIENCE

An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells

(2019) Li-Fang Chu et al.   Cell Reports

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

(2018) Katharina F. Sonnen et al.   CELL

ES cell-derived presomitic mesoderm-like tissues for analysis of synchronized oscillations in the segmentation clock

(2018) Marina Matsumiya et al.   DEVELOPMENT

What does time mean in development?

(2018) Miki Ebisuya et al.   DEVELOPMENT

Modeling human somite development and fibrodysplasia ossificans progressiva with induced pluripotent stem cells

(2018) Taiki Nakajima et al.   DEVELOPMENT

Conservation and Divergence of p53 Oscillation Dynamics across Species

(2017) Jacob Stewart-Ornstein et al.   Cell Systems

Self-Organization of Embryonic Genetic Oscillators into Spatiotemporal Wave Patterns

(2016) Charisios D. Tsiairis et al.   CELL

Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types

(2016) Kyle M. Loh et al.   CELL

Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy

(2015) Jérome Chal et al.   NATURE BIOTECHNOLOGY

Signalling dynamics in vertebrate segmentation

(2014) Alexis Hubaud et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Thinking out of the dish: what to learn about cortical development using pluripotent stem cells

(2014) Jelle van den Ameele et al.   TRENDS IN NEUROSCIENCES

Generation of eggs from mouse embryonic stem cells and induced pluripotent stem cells

(2013) Katsuhiko Hayashi et al.   Nature Protocols

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Transcript processing and export kinetics are rate-limiting steps in expressing vertebrate segmentation clock genes

(2013) N. P. Hoyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Patterning embryos with oscillations: structure, function and dynamics of the vertebrate segmentation clock

(2012) A. C. Oates et al.   DEVELOPMENT

Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling

(2012) Yusuke Okubo et al.   Nature Communications

Accelerating the Tempo of the Segmentation Clock by Reducing the Number of Introns in the Hes7 Gene

(2012) Yukiko Harima et al.   Cell Reports

Intronic delay is essential for oscillatory expression in the segmentation clock

(2011) Y. Takashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Klf4 reverts developmentally programmed restriction of ground state pluripotency

(2009) G. Guo et al.   DEVELOPMENT

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Notch Is a Critical Component of the Mouse Somitogenesis Oscillator and Is Essential for the Formation of the Somites

(2009) Zoltan Ferjentsik et al.   PLoS Genetics

Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways

(2008) Albert Goldbeter et al.   JOURNAL OF THEORETICAL BIOLOGY

Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation

(2008) T. Wataya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA