HARC as an open-shell strategy to bypass oxidative addition in Ullmann–Goldberg couplings

The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation

(2020) Patrick J. Sarver et al.   Nature Chemistry

Upscaling Photoredox Cross-Coupling Reactions in Batch Using Immersion-Well Reactors

(2020) Isabelle Grimm et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp2)–C(sp3) Cross-Coupling Methods by Library Synthesis

(2020) Amanda W. Dombrowski et al.   ACS Medicinal Chemistry Letters

Copper-Catalyzed Trifluoromethylation of Alkyl Bromides

(2019) David J. P. Kornfilt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Buchwald-Hartwig Amination after 25 Years

(2019) Ruth Dorel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Myth of d8 Copper(III)

(2019) Ida M. DiMucci et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes

(2019) Sandrine M. Hell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thirty Years of (TMS)3SiH: A Milestone in Radical-Based Synthetic Chemistry

(2018) Chryssostomos Chatgilialoglu et al.   CHEMICAL REVIEWS

Mechanism of the Ullmann Biaryl Ether Synthesis Catalyzed by Complexes of Anionic Ligands: Evidence for the Reaction of Iodoarenes with Ligated Anionic CuI Intermediates

(2018) Ramesh Giri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic synthesis provides opportunities to transform drug discovery

(2018) David C. Blakemore et al.   Nature Chemistry

A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes

(2018) Chip Le et al.   SCIENCE

Decarboxylative sp3 C–N coupling via dual copper and photoredox catalysis

(2018) Yufan Liang et al.   NATURE

A General Small-Scale Reactor To Enable Standardization and Acceleration of Photocatalytic Reactions

(2017) Chi “Chip” Le et al.   ACS Central Science

The merger of transition metal and photocatalysis

(2017) Jack Twilton et al.   Nature Reviews Chemistry

Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions

(2016) Paula Ruiz-Castillo et al.   CHEMICAL REVIEWS

Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross-Electrophile Coupling

(2016) Patricia Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alcohols as Latent Coupling Fragments for Metallaphotoredox Catalysis: sp3–sp2 Cross-Coupling of Oxalates with Aryl Halides

(2016) Xiaheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic alkylation of remote C–H bonds enabled by proton-coupled electron transfer

(2016) Gilbert J. Choi et al.   NATURE

A mechanistic investigation of the photoinduced, copper-mediated cross-coupling of an aryl thiol with an aryl halide

(2016) Miles W. Johnson et al.   Chemical Science

In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides

(2015) Phillip J. Milner et al.   ORGANOMETALLICS

Merging photoredox with nickel catalysis: Coupling of  -carboxyl sp3-carbons with aryl halides

(2014) Z. Zuo et al.   SCIENCE

A Versatile Approach to Ullmann C–N Couplings at Room Temperature: New Families of Nucleophiles and Electrophiles for Photoinduced, Copper-Catalyzed Processes

(2013) Daniel T. Ziegler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The role of organometallic copper(iii) complexes in homogeneous catalysis

(2013) Alicia Casitas et al.   Chemical Science

Photoinduced Ullmann C-N Coupling: Demonstrating the Viability of a Radical Pathway

(2012) S. E. Creutz et al.   SCIENCE

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Alternative Mechanistic Explanation for Ligand-Dependent Selectivities in Copper-CatalyzedN- andO-Arylation Reactions

(2010) Hai-Zhu Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diamine ligands in copper-catalyzed reactions

(2010) David S. Surry et al.   Chemical Science

Discovery of N-[(1-aryl-1H-indazol-5-yl)methyl]amides derivatives as smoothened antagonists for inhibition of the hedgehog pathway

(2009) Gabriella Dessole et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides

(2008) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis

(2008) Gwilherm Evano et al.   CHEMICAL REVIEWS