Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes

Telomerase Impinges on the Cellular Response to Oxidative Stress Through Mitochondrial ROS-Mediated Regulation of Autophagy

(2019) Paula Green et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impaired TFEB-mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-induced Liver Injury and Steatosis in Mice

(2018) Xiaojuan Chao et al.   GASTROENTEROLOGY

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

(2018) Valentina Celestini et al.   Cell Death & Disease

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

(2018) Juan I. Garaycoechea et al.   NATURE

Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance

(2017) K A Whelan et al.   ONCOGENE

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

(2017) Rebecca C. Rabinovitch et al.   Cell Reports

Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency

(2016) Qian Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Diisopropylethylamine/hexafluoroisopropanol-mediated ion-pairing ultra-high-performance liquid chromatography/mass spectrometry for phosphate and carboxylate metabolite analysis: utility for studying cellular metabolism

(2016) Lili Guo et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Acute and Chronic Ethanol Administration Differentially Modulate Hepatic Autophagy and Transcription Factor EB

(2015) Paul G. Thomes et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium

(2015) Yusuke Amanuma et al.   Scientific Reports

Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In Vivo

(2015) Xianbin Cai et al.   PLoS One

Esophageal Carcinoma

(2014) Anil K. Rustgi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute Ethanol Causes Hepatic Mitochondrial Depolarization in Mice: Role of Ethanol Metabolism

(2014) Zhi Zhong et al.   PLoS One

Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling

(2014) Y Feng et al.   Cell Death & Disease

ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes

(2013) Xin-ming Qi et al.   ACTA PHARMACOLOGICA SINICA

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Kinetics of DNA Adduct Formation in the Oral Cavity after Drinking Alcohol

(2012) S. Balbo et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture

(2012) Jiri Kalabis et al.   Nature Protocols

Acute Activation of AMP-Activated Protein Kinase Prevents H2O2-Induced Premature Senescence in Primary Human Keratinocytes

(2012) Yasuo Ido et al.   PLoS One

Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress

(2011) X Liu et al.   CELL DEATH AND DIFFERENTIATION

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption

(2009) Philip J Brooks et al.   PLOS MEDICINE

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

(2008) Yongke Lu et al.   HEPATOLOGY

The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model

(2008) Angelica Butura et al.   JOURNAL OF HEPATOLOGY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL