Kukoamine A Protects against NMDA-Induced Neurotoxicity Accompanied with Down-Regulation of GluN2B-Containing NMDA Receptors and Phosphorylation of PI3K/Akt/GSK-3β Signaling Pathway in Cultured Primary Cortical Neurons

Inhibitory activities of kukoamines A and B from Lycii Cortex on amyloid aggregation related to Alzheimer’s disease and type 2 diabetes

(2019) Gandan Jiang et al.   Journal of Natural Medicines

The effects of Lycii Radicis Cortex on RANKL-induced osteoclast differentiation and activation in RAW 264.7 cells

(2016) JAE-HYUN KIM et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Disturbed Neurotransmitter Transporter Expression in Alzheimer’s Disease Brain

(2016) Kevin H. Chen et al.   JOURNAL OF ALZHEIMERS DISEASE

Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation

(2016) Qiaoping Wang et al.   Scientific Reports

Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models

(2012) Youngkyung Kim et al.   PAIN

2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity

(2011) Dean G. Brown et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances

(2011) Neng-Wei Hu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Neu2000, an NR2B-selective, moderate NMDA receptor antagonist and potent spin trapping molecule for stroke

(2010) S.J. Cho et al.   DRUG NEWS & PERSPECTIVES

Long-term depression in the CNS

(2010) Graham L. Collingridge et al.   NATURE REVIEWS NEUROSCIENCE

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

Cortex Lycii Radicis extracts improve insulin resistance and lipid metabolism in obese-diabetic rats

(2008) Zhen Ye et al.   PHYTOTHERAPY RESEARCH