Characteristics of SARS-CoV-2 and COVID-19

Q&A: The novel coronavirus outbreak causing COVID-19

(2020) Dale Fisher et al.   BMC Medicine

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Consistent Detection of 2019 Novel Coronavirus in Saliva

(2020) Kelvin Kai-Wang To et al.   CLINICAL INFECTIOUS DISEASES

Differential diagnosis of illness in patients under investigation for the novel coronavirus (SARS-CoV-2), Italy, February 2020

(2020) Licia Bordi et al.   Eurosurveillance

Rapid establishment of laboratory diagnostics for the novel coronavirus SARS-CoV-2 in Bavaria, Germany, February 2020

(2020) Regina Konrad et al.   Eurosurveillance

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

(2020) Chih-Cheng Lai et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China

(2020) David S. Hui et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

(2020) Zunyou Wu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-polymerase chain reaction assay validated in vitro and with clinical specimens

(2020) Jasper Fuk-Woo Chan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents

(2020) G. Kampf et al.   JOURNAL OF HOSPITAL INFECTION

Recent insights into 2019-nCoV: a brief but comprehensive review

(2020) Qingmei Han et al.   JOURNAL OF INFECTION

Emergence of SARS-like coronavirus poses new challenge in China

(2020) Ruichen Wang et al.   JOURNAL OF INFECTION

A Familial Cluster of Infection Associated With the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period

(2020) Ping Yu et al.   JOURNAL OF INFECTIOUS DISEASES

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

2019-nCoV transmission through the ocular surface must not be ignored

(2020) Cheng-wei Lu et al.   LANCET

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

(2020) Huijun Chen et al.   LANCET

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

(2020) Jasper Fuk-Woo Chan et al.   LANCET

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study

(2020) Joseph T Wu et al.   LANCET

Viral load of SARS-CoV-2 in clinical samples

(2020) Yang Pan et al.   LANCET INFECTIOUS DISEASES

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

(2020) Lirong Zou et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

(2020) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chest CT Findings in 2019 Novel Coronavirus (2019-nCoV) Infections from Wuhan, China: Key Points for the Radiologist

(2020) Jeffrey P. Kanne   RADIOLOGY

Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing

(2020) Xingzhi Xie et al.   RADIOLOGY

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Return of the Coronavirus: 2019-nCoV

(2020) Lisa E. Gralinski et al.   Viruses-Basel

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

(2020) Xiaolong Tian et al.   Emerging Microbes & Infections

An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies

(2020) Shibo Jiang et al.   Emerging Microbes & Infections

Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes

(2020) Wei Zhang et al.   Emerging Microbes & Infections

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

(2020) Jasper Fuk-Woo Chan et al.   Emerging Microbes & Infections

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

(2020) Xiaobo Yang et al.   Lancet Respiratory Medicine

On the origin and continuing evolution of SARS-CoV-2

(2020) Xiaolu Tang et al.   National Science Review

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Characteristics of and Public Health Responses to the Coronavirus Disease 2019 Outbreak in China

(2020) Sheng-Qun Deng et al.   Journal of Clinical Medicine

Initial Cluster of Novel Coronavirus (2019-nCoV) Infections in Wuhan, China Is Consistent with Substantial Human-to-Human Transmission

(2020) Hiroshi Nishiura et al.   Journal of Clinical Medicine

Weathering COVID-19 storm: Successful control measures of five Asian countries

(2020) Ning Lu et al.   AMERICAN JOURNAL OF INFECTION CONTROL

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

(2020) B. Coutard et al.   ANTIVIRAL RESEARCH

A Genomic Perspective on the Origin and Emergence of SARS-CoV-2

(2020) Yong-Zhen Zhang et al.   CELL

Pathogenesis of SARS-CoV-2 in transgenic mice expressing human angiotensin-converting enzyme 2

(2020) Ren-Di Jiang et al.   CELL

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Infection and Rapid Transmission of SARS-CoV-2 in Ferrets

(2020) Young-Il Kim et al.   Cell Host & Microbe

Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19

(2020) Annsea Park et al.   Cell Host & Microbe

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis

(2020) Shi-Hui Sun et al.   Cell Host & Microbe

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility

(2020) Jasper Fuk-Woo Chan et al.   CLINICAL INFECTIOUS DISEASES

Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19)

(2020) Li Guo et al.   CLINICAL INFECTIOUS DISEASES

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

(2020) Xueting Yao et al.   CLINICAL INFECTIOUS DISEASES

Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study

(2020) Andrea Giacomelli et al.   CLINICAL INFECTIOUS DISEASES

Umifenovir treatment is not associated with improved outcomes in patients with coronavirus disease 2019: a retrospective study

(2020) N. Lian et al.   CLINICAL MICROBIOLOGY AND INFECTION

A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein

(2020) Hong Zhou et al.   CURRENT BIOLOGY

Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak

(2020) Tao Zhang et al.   CURRENT BIOLOGY

Association between age and clinical characteristics and outcomes of COVID-19

(2020) Yang Liu et al.   EUROPEAN RESPIRATORY JOURNAL

Pulmonary Pathology of Early Phase COVID‐19 Pneumonia in a Patient with a Benign Lung Lesion

(2020) Zhi Zeng et al.   HISTOPATHOLOGY

Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event

(2020) D. Paraskevis et al.   INFECTION GENETICS AND EVOLUTION

SARS-CoV-2 was already spreading in France in late December 2019

(2020) A. Deslandes et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

(2020) Chenguang Shen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State

(2020) Eli S. Rosenberg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Rapid random access detection of the novel SARS-coronavirus-2 (SARS-CoV-2, previously 2019-nCoV) using an open access protocol for the Panther Fusion

(2020) Anne K. Cordes et al.   JOURNAL OF CLINICAL VIROLOGY

Arbidol monotherapy is superior to lopinavir/ritonavir in treating COVID-19

(2020) Zhen Zhu et al.   JOURNAL OF INFECTION

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

(2020) Feng-Cai Zhu et al.   LANCET

Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial

(2020) Ivan Fan-Ngai Hung et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study

(2020) Kelvin Kai-Wang To et al.   LANCET INFECTIOUS DISEASES

Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study

(2020) Jianbo Tian et al.   LANCET ONCOLOGY

A human neutralizing antibody targets the receptor binding site of SARS-CoV-2

(2020) Rui Shi et al.   NATURE

Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins

(2020) Kangpeng Xiao et al.   NATURE

Identifying SARS-CoV-2 related coronaviruses in Malayan pangolins

(2020) Tommy Tsan-Yuk Lam et al.   NATURE

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

Virological assessment of hospitalized patients with COVID-2019

(2020) Roman Wölfel et al.   NATURE

Respiratory disease in rhesus macaques inoculated with SARS-CoV-2

(2020) Vincent J. Munster et al.   NATURE

Infection of dogs with SARS-CoV-2

(2020) Thomas H. C. Sit et al.   NATURE

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

(2020) Linlin Bao et al.   NATURE

The proximal origin of SARS-CoV-2

(2020) Kristian G. Andersen et al.   NATURE MEDICINE

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Droplets and Aerosols in the Transmission of SARS-CoV-2

(2020) Matthew Meselson   NEW ENGLAND JOURNAL OF MEDICINE

Remdesivir for the Treatment of Covid-19 — Preliminary Report

(2020) John H. Beigel et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 Infection in Children

(2020) Xiaoxia Lu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19

(2020) Joshua Geleris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Compassionate Use of Remdesivir for Patients with Severe Covid-19

(2020) Jonathan Grein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1

(2020) Neeltje van Doremalen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The airborne lifetime of small speech droplets and their potential importance in SARS-CoV-2 transmission

(2020) Valentyn Stadnytskyi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effective treatment of severe COVID-19 patients with tocilizumab

(2020) Xiaoling Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phylogenetic network analysis of SARS-CoV-2 genomes

(2020) Peter Forster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effectiveness of convalescent plasma therapy in severe COVID-19 patients

(2020) Kai Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

(2020) Yan Wu et al.   SCIENCE

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

(2020) Abishek Chandrashekar et al.   SCIENCE

Development of an inactivated vaccine candidate for SARS-CoV-2

(2020) Qiang Gao et al.   SCIENCE

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)

(2020) Ruiyun Li et al.   SCIENCE

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2

(2020) Jianzhong Shi et al.   SCIENCE

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

(2020) Barry Rockx et al.   SCIENCE

A human monoclonal antibody blocking SARS-CoV-2 infection

(2020) Chunyan Wang et al.   Nature Communications

Immunogenicity of a DNA vaccine candidate for COVID-19

(2020) Trevor R. F. Smith et al.   Nature Communications

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

(2020) Xiuyuan Ou et al.   Nature Communications

Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study

(2020) Tao Chen et al.   BMJ-British Medical Journal

The hallmarks of COVID-19 disease

(2020) Daolin Tang et al.   PLoS Pathogens

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro

(2020) Xi Wang et al.   Cell Discovery

Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study

(2020) Qingxian Cai et al.   Engineering

Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2

(2020) Renfei Lu et al.   VIROLOGICA SINICA

Prolonged presence of SARS-CoV-2 viral RNA in faecal samples

(2020) Yongjian Wu et al.   Lancet Gastroenterology & Hepatology

Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants

(2020) Muhammad Tahir ul Qamar et al.   Journal of Pharmaceutical Analysis

Antiviral activities of type I interferons to SARS-CoV-2 infection

(2020) Emily Mantlo et al.   ANTIVIRAL RESEARCH

Type 1 interferons as a potential treatment against COVID-19

(2020) Erwan Sallard et al.   ANTIVIRAL RESEARCH

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020

(2020) Nadia Oreshkova et al.   Eurosurveillance

Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes

(2020) Shengli Xia et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Broad and differential animal ACE2 receptor usage by SARS-CoV-2

(2020) Xuesen Zhao et al.   JOURNAL OF VIROLOGY

Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

(2020) Catherine F Houlihan et al.   LANCET

Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial

(2020) Feng-Cai Zhu et al.   LANCET

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

(2020) Pedro M Folegatti et al.   LANCET

SARS-CoV-2 RNA more readily detected in induced sputum than in throat swabs of convalescent COVID-19 patients

(2020) Huanqin Han et al.   LANCET INFECTIOUS DISEASES

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics

(2020) Eskild Petersen et al.   LANCET INFECTIOUS DISEASES

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

(2020) Brandi N. Williamson et al.   NATURE

Potently neutralizing and protective human antibodies against SARS-CoV-2

(2020) Seth J. Zost et al.   NATURE

SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

(2020) Antoni G. Wrobel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

COVID-19 and migrant workers: Lack of data and need for specific management

(2020) B. Joob et al.   PUBLIC HEALTH

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

(2020) Hongjing Gu et al.   SCIENCE

Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

(2020) Yvonne C. F. Su et al.   mBio

Transplacental transmission of SARS-CoV-2 infection

(2020) Alexandre J. Vivanti et al.   Nature Communications

SARS-CoV-2 is transmitted via contact and via the air between ferrets

(2020) Mathilde Richard et al.   Nature Communications

Meat plants—a new front line in the covid-19 pandemic

(2020) John Middleton et al.   BMJ-British Medical Journal

Authors’ correction for Euro Surveill. 2020;25(32)

(2020)   Eurosurveillance

Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (Manis javanica)

(2019) Ping Liu et al.   Viruses-Basel

Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats

(2018) Dan Hu et al.   Emerging Microbes & Infections

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

(2017) Yuan Yuan et al.   Nature Communications

Protease inhibitors targeting coronavirus and filovirus entry

(2015) Yanchen Zhou et al.   ANTIVIRAL RESEARCH

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

(2014) Adriaan H. de Wilde et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Simultaneous Treatment of Human Bronchial Epithelial Cells with Serine and Cysteine Protease Inhibitors Prevents Severe Acute Respiratory Syndrome Coronavirus Entry

(2012) M. Kawase et al.   JOURNAL OF VIROLOGY