A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

TIGIT is upregulated by HIV-1 infection and marks a highly functional adaptive and mature subset of natural killer cells

(2020) Elena Vendrame et al.   AIDS

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells

(2019) David G Saliba et al.   eLife

A tissue-like platform for studying engineered quiescent human T-cells' interactions with dendritic cells

(2019) Enas Abu Shah et al.   eLife

Immunotherapy with immune checkpoint inhibitors in colorectal cancer: what is the future beyond deficient mismatch-repair tumours?

(2019) Nicolas Huyghe et al.   Gastroenterology Report

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

(2018) Franck Pagès et al.   LANCET

Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing

(2018) Xinyi Guo et al.   NATURE MEDICINE

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

(2018) Lei Zhang et al.   NATURE

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

(2017) Enfu Hui et al.   SCIENCE

Visualizing dynamic microvillar search and stabilization during ligand detection by T cells

(2017) En Cai et al.   SCIENCE

CD58 mutations are common in Hodgkin lymphoma cell lines and loss of CD58 expression in tumor cells occurs in Hodgkin lymphoma patients who relapse

(2016) F R Abdul Razak et al.   GENES AND IMMUNITY

Isolation and Characterization of an HLA-DPB1*04

(2016) Xin Yao et al.   JOURNAL OF IMMUNOTHERAPY

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

CD58/CD2 Is the Primary Costimulatory Pathway in Human CD28−CD8+T Cells

(2015) Judith Leitner et al.   JOURNAL OF IMMUNOLOGY

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

(2015) Eoin F. McKinney et al.   NATURE

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

(2015) Sudha Kumari et al.   eLife

Phenotypic analysis of T cells infiltrating colon cancers: Correlations with oncogenetic status

(2015) Mircea Chirica et al.   OncoImmunology

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

(2014) Kaushik Choudhuri et al.   NATURE

Cutting Edge: DNAX Accessory Molecule 1-Deficient CD8+ T Cells Display Immunological Synapse Defects That Impair Antitumor Immunity

(2013) K. M. Ramsbottom et al.   JOURNAL OF IMMUNOLOGY

Strength of PD-1 signaling differentially affects T-cell effector functions

(2013) F. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Targeting of Human Alloresponsive CD8+ Effector Memory T Cells Based on CD2 Expression

(2010) D. J. Lo et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Inhibition and Activation by CD244 Depends on CD2 and Phospholipase C-γ1

(2009) Nicholas G. Clarkson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells

(2009) Yoshihisa Kaizuka et al.   JOURNAL OF CELL BIOLOGY

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

(2009) Soumya Raychaudhuri et al.   NATURE GENETICS

The role of the CD58 locus in multiple sclerosis

(2009) P. L. De Jager et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micropatterning of costimulatory ligands enhances CD4+ T cell function

(2008) K. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA