Functional CRISPR dissection of gene networks controlling human regulatory T cell identity
出版年份 2020 全文链接
标题
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity
作者
关键词
-
出版物
NATURE IMMUNOLOGY
Volume 21, Issue 11, Pages 1456-1466
出版商
Springer Science and Business Media LLC
发表日期
2020-09-29
DOI
10.1038/s41590-020-0784-4
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
- (2020) Naganari Ohkura et al. IMMUNITY
- Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function
- (2019) Catherine Konopacki et al. NATURE IMMUNOLOGY
- HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma
- (2019) Jason Miska et al. Cell Reports
- Next-generation regulatory T cell therapy
- (2019) Leonardo M. R. Ferreira et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity
- (2018) David Wang et al. Cell Reports
- Modulation of EZH2 expression in T cells improves efficacy of anti–CTLA-4 therapy
- (2018) Sangeeta Goswami et al. JOURNAL OF CLINICAL INVESTIGATION
- Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
- (2018) Eric Shifrut et al. CELL
- Guide Swap enables genome-scale pooled CRISPR–Cas9 screening in human primary cells
- (2018) Pamela Y. Ting et al. NATURE METHODS
- The Plasticity and Stability of Regulatory T Cells during Viral-Induced Inflammatory Lesions
- (2017) Siddheshvar Bhela et al. JOURNAL OF IMMUNOLOGY
- Stability and function of regulatory T cells expressing the transcription factor T-bet
- (2017) Andrew G. Levine et al. NATURE
- Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
- (2017) Hyun Min Kang et al. NATURE BIOTECHNOLOGY
- Control of Foxp3 stability through modulation of TET activity
- (2016) Xiaojing Yue et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Automated mapping of phenotype space with single-cell data
- (2016) Nikolay Samusik et al. NATURE METHODS
- Mutations in HIVEP2 are associated with developmental delay, intellectual disability, and dysmorphic features
- (2016) Hallie Steinfeld et al. NEUROGENETICS
- Loss-of-function variants in HIVEP2 are a cause of intellectual disability
- (2015) Siddharth Srivastava et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy
- (2015) Magali Noval Rivas et al. IMMUNITY
- An interactive reference framework for modeling a dynamic immune system
- (2015) M. H. Spitzer et al. SCIENCE
- Stable inhibitory activity of regulatory T cells requires the transcription factor Helios
- (2015) H.-J. Kim et al. SCIENCE
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
- (2015) Jeffrey A. Bluestone et al. Science Translational Medicine
- The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations
- (2014) C. Schmidl et al. BLOOD
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease
- (2014) Masaki Miyazaki et al. NATURE IMMUNOLOGY
- Easy quantitative assessment of genome editing by sequence trace decomposition
- (2014) Eva K. Brinkman et al. NUCLEIC ACIDS RESEARCH
- “Do you catch my drift?”
- (2014) Timothy Hannon TRANSFUSION
- Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
- (2013) Noriko Komatsu et al. NATURE MEDICINE
- An N-Terminal Mutation of the Foxp3 Transcription Factor Alleviates Arthritis but Exacerbates Diabetes
- (2012) Jaime Darce et al. IMMUNITY
- Genome-wide Repression of NF-κB Target Genes by Transcription Factor MIBP1 and Its Modulation by O -Linked β- N -Acetylglucosamine ( O -GlcNAc) Transferase
- (2012) Yuji Iwashita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
- (2012) Wenxian Fu et al. NATURE IMMUNOLOGY
- Transcription factor Foxp3 and its protein partners form a complex regulatory network
- (2012) Dipayan Rudra et al. NATURE IMMUNOLOGY
- Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
- (2012) E. T. Clambey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of FOXP3-negative regulatory T-like (CD4+CD25+CD127low) cells in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome
- (2011) Keisuke Otsubo et al. CLINICAL IMMUNOLOGY
- CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game
- (2011) S. A. Long et al. JOURNAL OF IMMUNOLOGY
- Dampening of death pathways by schnurri-2 is essential for T-cell development
- (2011) Tracy L. Staton et al. NATURE
- Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation
- (2011) Marc Beyer et al. NATURE IMMUNOLOGY
- The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
- (2011) Erika Cretney et al. NATURE IMMUNOLOGY
- Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease
- (2011) Margarita Dominguez-Villar et al. NATURE MEDICINE
- Foxo Transcription Factors Control Regulatory T Cell Development and Function
- (2010) Yann M. Kerdiles et al. IMMUNITY
- Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells
- (2010) A. M. Thornton et al. JOURNAL OF IMMUNOLOGY
- Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+inducible regulatory T cells
- (2009) Sven Klunker et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
- (2009) Ye Zheng et al. NATURE
- Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes
- (2008) A. L. Putnam et al. DIABETES
- DNA methylation controls Foxp3 gene expression
- (2008) Julia K. Polansky et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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