Synthesis of azetidines via visible-light-mediated intermolecular [2+2] photocycloadditions

Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity

(2020) Martins S. Oderinde et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Sterically Hindered Primary Amines by Concurrent Tandem Photoredox Catalysis

(2020) Michael C. Nicastri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Escaping from Flatland: [2 + 2] Photocycloaddition; Conformationally Constrained sp3-rich Scaffolds for Lead Generation

(2019) Brian Cox et al.   ACS Medicinal Chemistry Letters

Photosensitized Intermolecular Carboimination of Alkenes through the Persistent Radical Effect

(2019) Tuhin Patra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Energy transfer catalysis mediated by visible light: principles, applications, directions

(2018) Felix Strieth-Kalthoff et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of a Bicyclic Azetidine with In Vivo Antimalarial Activity Enabled by Stereospecific, Directed C(sp3)–H Arylation

(2017) Micah Maetani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in the chemistry of metallated azetidines

(2017) Daniele Antermite et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Recent Advances in the Synthesis of Cyclobutanes by Olefin [2 + 2] Photocycloaddition Reactions

(2016) Saner Poplata et al.   CHEMICAL REVIEWS

[2 + 2] Photocycloadditions between the Carbon–Nitrogen Double Bonds of Imines and Carbon–Carbon Double Bonds

(2016) Ryu Sakamoto et al.   ORGANIC LETTERS

Patent Review of Manufacturing Routes to Recently Approved Oncology Drugs: Ibrutinib, Cobimetinib, and Alectinib

(2016) David L. Hughes   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Advances in Photocatalysis: A Microreview of Visible Light Mediated Ruthenium and Iridium Catalyzed Organic Transformations

(2016) Kip Teegardin et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities

(2014) Erick M. Carreira et al.   CHEMICAL REVIEWS

Discovery and Development of Janus Kinase (JAK) Inhibitors for Inflammatory Diseases

(2014) James D. Clark et al.   JOURNAL OF MEDICINAL CHEMISTRY

Visible Light Photocatalysis of [2+2] Styrene Cycloadditions by Energy Transfer

(2012) Zhan Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitigating Heterocycle Metabolism in Drug Discovery

(2012) David J. St. Jean et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries

(2012) Jason T. Lowe et al.   JOURNAL OF ORGANIC CHEMISTRY

Escape from Flatland 2: complexity and promiscuity

(2012) Frank Lovering   MedChemComm

N-Aminoazetidinecarboxylic Acid: Direct Access to a Small-Ring Hydrazino Acid

(2010) Valérie Declerck et al.   JOURNAL OF ORGANIC CHEMISTRY

7-Sulfonamido-3-benzazepines as potent and selective 5-HT2C receptor agonists: Hit-to-lead optimization

(2009) Paul V. Fish et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent

(2009) Alan Brown et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Role of Biotransformation Studies in Minimizing Metabolism-Related Liabilities in Drug Discovery

(2008) Yue-Zhong Shu et al.   AAPS Journal

Novel Syntheses of Azetidines and Azetidinones

(2008) Alberto Brandi et al.   CHEMICAL REVIEWS

Regio- and Stereochemistry of [2 + 2] Photocycloadditions of Imines to Alkenes: A Computational and Experimental Study

(2008) Diego Sampedro et al.   JOURNAL OF ORGANIC CHEMISTRY