期刊
MOLECULES
卷 25, 期 20, 页码 -出版社
MDPI
DOI: 10.3390/molecules25204677
关键词
benzazoles; benzimidazoles; benzothiazoles; benzoxazole; fluorine; biological activities
资金
- His Majesty Trust Fund [SR/SCI/CHEM/19/01]
Fluorine-containing heterocycles continue to receive considerable attention due to their unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules imparts a significant enhancement their biological activities compared to non-fluorinated molecules. In this short review, we will highlight the importance of incorporating fluorine as a basic appendage in benzothiazole and benzimidazole skeletons. The chemistry and pharmacological activities of heterocycles containing fluorine during the past years are compiled and discussed.
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