Review
Food Science & Technology
Esther Ramirez-Moreno, Jose Arias-Rico, Reyna Cristina Jimenez-Sanchez, Diego Estrada-Luna, Angelica Sarai Jimenez-Osorio, Quinatzin Yadira Zafra-Rojas, Jose Alberto Ariza-Ortega, Olga Rocio Flores-Chavez, Lizbeth Morales-Castillejos, Eli Mireya Sandoval-Gallegos
Summary: Obesity is a disease characterized by inflammation in adipose tissue, caused by immune cell infiltration, increased proinflammatory molecule secretion, and decreased anti-inflammatory molecule secretion. It also increases the risk of cardiovascular diseases, diabetes, and cancer. Natural products such as polyphenols and fiber have potential anti-inflammatory effects and play an important role in the prevention and treatment of obesity and other non-communicable diseases.
Review
Food Science & Technology
Sabira Sultana, Abdelhakim Bouyahya, Maksim Rebezov, Mohammad Ali Shariati, Abdelaali Balahbib, Aya Khouchlaa, Ouadie Mohamed El Yaagoubi, Adnan Khaliq, Nasreddine El Omari, Saad Bakrim, Gokhan Zengin, Muhammad Akram, Mars Khayrullin, Irina Bogonosova, Shafi Mahmud, Jesus Simal-Gandara
Summary: For individuals living with progressive cancer, nutritional therapy and exercise are important factors in improving health and quality of life. Cancer survivors and patients are encouraged to seek knowledge on diet, exercise, and supplements to maintain treatment outcomes, living quality, and survival. A healthy diet plays a significant role in cancer treatment.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Priscila Schilrreff, Ulrike Alexiev
Summary: This review discusses the crucial role of chronic inflammation in chronic wounds and its close association with immune regulation. The dysregulation of the immune system leads to persistent inflammation and impaired wound healing, resulting in chronic skin wounds. Furthermore, it explores the potential of natural bioactive compounds in wound treatment, particularly focusing on compounds with antioxidant, anti-inflammatory, and antibacterial activities, as well as recent advancements in wound treatments utilizing nanotechnology or new biomaterial platforms.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Shahida Anusha Siddiqui, Nur Alim Bahmid, Ahmed Taha, Abdel-Moneim Eid Abdel-Moneim, Abdelrazeq M. Shehata, Chen Tan, Mohammad Saeed Kharazmi, Yuan Li, Elham Assadpour, Roberto Castro-Munoz, Seid Mahdi Jafari
Summary: This study reviews the application of nanoencapsulation in animal feedings and relevant drugs. Nanoencapsulation design can protect feed bioactives and improve their absorption and release in animals. Chitosan is found to be the most effective carrier. Nanoparticles and nanocapsules are commonly used nanocarriers. Nanofibers, nanohydrogels, and nanoemulsions have not been applied in feeds yet. For ruminants, nano-minerals, vitamins, phytochemicals, essential fatty acids, and drugs are encapsulated using nanoparticles for improved delivery and bioavailability. Safety and regulatory issues, as well as advantages and disadvantages of nanoencapsulation in animal feeds, are also discussed.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Review
Agriculture, Multidisciplinary
Yue Zhang, Qing Chen, Xiong Fu, Siming Zhu, Qiang Huang, Chao Li
Summary: This review summarizes the regulatory effects and molecular mechanisms of dietary bioactive compounds on nonalcoholic fatty liver disease (NAFLD) through the modulation of autophagy. Existing research has demonstrated that dietary bioactive compounds can improve various aspects of NAFLD, such as lipid metabolism, insulin resistance, endoplasmic reticulum stress, and inflammation, by targeting autophagy-mediated signaling pathways.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Juan M. Espinosa, Jose M. Castellano, Silvia Garcia-Rodriguez, Angelica Quintero-Florez, Natalia Carrasquilla, Javier S. Perona
Summary: Microglial cells contribute to Alzheimer's disease by triggering an inflammatory response that leads to neuronal death. The presence of amyloid-beta in the brain is associated with alterations in the blood-brain barrier and permeation of triglyceride-rich lipoproteins (TRL). In this study, lab-made TRL were used as carriers of lipophilic bioactive compounds to modulate the inflammatory response of microglial cells. The inclusion of oleanolic acid, alpha-tocopherol, and beta-sitosterol in TRL reduced the release of proinflammatory cytokines, such as IL-1 beta, IL-6, and TNF-alpha, as well as NO and iNOS generation. These findings suggest the potential therapeutic application of these lipophilic bioactive compounds in the treatment of Alzheimer's disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Medicinal
Andres Sanchez-Ruiz, Gonz a l o Colmenarejo
Summary: This study retrieves and analyzes the interactions between food compounds and human proteins using the FooDB and ChEMBL databases. The results show a low target assignment for the compounds and multiple gaps in the chemobiological space. By using cheminformatic approaches, a higher target assignment is achieved, filling many of the gaps and providing target hypotheses for fast testing.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
(2022)
Review
Food Science & Technology
Ana Paula da Fonseca Machado, Roberto de Paula do Nascimento, Mariana da Rocha Alves, Livia Mateus Reguengo, Mario Roberto Marostica Junior
Summary: Latin America boasts a variety of native plants, including the Astrocaryum genus, which have potential medicinal and technological uses. Two native Brazilian fruits, tucuma-do-Amazonas and tucuma-do-Para, are rich in antioxidants and bioactive compounds, showing promise in preventing and treating diseases. Additionally, tucuma plants have potential industrial applications such as biofuel production and alternative packaging materials.
FOOD RESEARCH INTERNATIONAL
(2022)
Review
Biochemistry & Molecular Biology
Marta Pelczynska, Malgorzata Moszak, Agnieszka Wesolek, Pawel Bogdanski
Summary: Dietary patterns, specifically those containing bioactive food compounds such as polyphenols, unsaturated fatty acids, and probiotics, show promise in preventing and treating obesity-induced inflammation. These compounds modulate the secretion of inflammatory molecules, regulate gene expression, and modify signaling pathways involved in the inflammatory response. However, further research is needed to determine optimal strategies for their intake, and global education is necessary to promote the advantages of consuming bioactive food compounds and combat unhealthy dietary patterns.
Review
Pharmacology & Pharmacy
Kondeti R. Shanmugam, Bhasha Shanmugam, Ganjikunta Subbaiah, Sahukari Ravi, Kesireddy S. Reddy
Summary: Diabetes is a major public health problem worldwide, and alternative medicine is needed for treatment. Many herbal plants and their bioactive compounds show anti-diabetic effects, indicating therapeutic potential.
CURRENT PHARMACEUTICAL DESIGN
(2021)
Review
Chemistry, Medicinal
Farid Menaa, Udari Wijesinghe, Gobika Thiripuranathar, Norah A. Althobaiti, Aishah E. Albalawi, Barkat Ali Khan, Bouzid Menaa
Summary: Marine algae are a rich source of bioactive nutrients, which can be extracted and purified for nanotheranostic purposes using various techniques. They offer ease of handling, profitability, and sustainability, holding potential significance for the development of therapeutic agents.
Review
Biochemistry & Molecular Biology
Rossana Galassi, Lorenzo Luciani, Junbiao Wang, Silvia Vincenzetti, Lishan Cui, Augusto Amici, Stefania Pucciarelli, Cristina Marchini
Summary: This article reviews recent scientific findings on two classes of gold compounds containing phosphane or carbene ligands, as well as the recent developments in the application of Auranofin for breast cancers.
Article
Biochemistry & Molecular Biology
Dana Kumprechtova, Thibaut Chabrillat, Simon Guillaume, Sylvain Kerros, Romana Kadek, Eva Indrova, Josef Illek
Summary: The study indicated that the plant bioactive compound with Brazilian green propolis administered to dairy cows during calving had a positive impact on their energy and inflammatory status.
Review
Plant Sciences
Sheikh Rashel Ahmed, Muhammad Fazle Rabbee, Anindita Roy, Rocky Chowdhury, Anik Banik, Khadizatul Kubra, Mohammed Mehadi Hassan Chowdhury, Kwang-Hyun Baek
Summary: When functioning properly, the stomach is the center of both physical and mental satisfaction. Gastrointestinal disorders, caused by infections and physiochemical abnormalities, are now widespread and are mostly inflammatory diseases. Treatment with medicinal plants and their active components is considered a safer and more effective option compared to synthetic drugs.
Article
Medicine, Research & Experimental
Antonio Jose Ruiz-Alcaraz, Maria Antonia Martinez-Sanchez, Pilar Garcia-Penarrubia, Maria Martinez-Esparza, Bruno Ramos-Molina, Diego A. Moreno
Summary: The study found that phytochemicals from Brassica plants have significant anti-inflammatory activity in a human macrophage-like cell model, offering potential as therapeutic leads for treating or preventing human chronic inflammation and related diseases.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Biochemistry & Molecular Biology
Ivo Jose Curcino Vieira, Elaine Rodrigues Figueiredo, Milena Goncalves Curcino Vieira, Almir Ribeiro de Carvalho Junior, Michel de Souza Passos, Samyra Imad da Silva Boeno, Otoniel Aquino Azevedo, Raimundo Braz-Filho
Article
Chemistry, Multidisciplinary
Maria Lucy de Assis, Marco Antonio G. B. Gomes, Larissa L. da Cruz, Michel De S. Passos, Silvia M. F. Pereira, Mariana B. S. Arantes, Daniela B. Oliveira, Ivo J. C. Vieira
Article
Chemistry, Medicinal
Michel de S. Passos, Almir R. de Carvalho Junior, Samyra Boeno, Lorena de L. Gloria das Virgens, Sanderson Dias Calixto, Thatiana Lopes Bia Ventura, Elena Lassounskaia, Raimundo Braz-Filho, Ivo J. Curcino Vieira
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
(2019)
Article
Biochemistry & Molecular Biology
Almir Ribeiro de Carvalho Junior, Rafaela Oliveira Ferreira, Michel de Souza Passos, Samyra Imad da Silva Boeno, Lorena de Lima Gloria das Virgens, Thatiana Lopes Bia Ventura, Sanderson Dias Calixto, Elena Lassounskaia, Mario Geraldo de Carvalho, Raimundo Braz-Filho, Ivo Jose Curcino Vieira
Article
Chemistry, Medicinal
Samyra I. S. Boeno, Michel de S. Passos, Mariana Felix, Sanderson D. Calixto, R. C. Junior Almir, Lara F. Barbosa Siqueira, Michelle F. Muzitano, Raimundo Braz-Filho, Ivo J. Curcino Vieira
NATURAL PRODUCT COMMUNICATIONS
(2020)
Article
Chemistry, Applied
Nathania S. Mendes, Silvia M. F. Pereira, Mariana B. S. Arantes, Lorena L. Gloria, Clara R. Nunes, Michel de S. Passos, Ivo J. C. Vieira, Luana P. de Moraes, Rosana Rodrigues, Daniela B. Oliveira
Review
Biochemistry & Molecular Biology
Thalya Soares R. Nogueira, Michel de S. Passos, Lara Pessanha S. Nascimento, Mayara Barreto de S. Arantes, Noemi O. Monteiro, Samyra Imad da S. Boeno, Almir de Carvalho Junior, Otoniel de A. Azevedo, Wagner da S. Terra, Milena Goncalves C. Vieira, Raimundo Braz-Filho, Ivo J. Curcino Vieira
Review
Plant Sciences
Michel Souza Passos, Thalya Soares Ribeiro Nogueira, Otoniel de Aquino Azevedo, Milena Goncalves Curcino Vieira, Wagner da Silva Terra, Raimundo Braz-Filho, Ivo Jose Curcino Vieira
Summary: Limonoids, found in the families Meliaceae and Rutaceae, are pharmacologically active compounds that provide the bitter principles in citrus fruits. The Trichilia genus in the Meliaceae family is known for its diverse limonoids with various biological activities, distributed across the Americas, Africa, and Asia. Intact rings and ring-seco limonoids are more common in American and African species, while rearranged limonoids are prevalent in Asian species.
PHYTOCHEMISTRY REVIEWS
(2021)
Article
Plant Sciences
Samyra Imad Boeno, Ivo Jose Curcino Vieira, Raimundo Braz-Filho, Michel de Souza Passos, Milena Goncalves Curcino Vieira, Maria Fernanda Alves do Nascimento, Douglas Costa Gontijo, Alaide Braga de Oliveira
Summary: The study aimed to investigate the antiplasmodial and cytotoxic effects of compounds isolated from Homalolepis suffruticosa roots and its methanol extract, as well as to dereplicate the extract for metabolic profiling. The isolated compounds and methanol extract showed good antiplasmodial activity, supporting the traditional medicinal use of Simaroubaceae species as antimalarial drugs.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)