COVID‐19 drug repurposing: A review of computational screening methods, clinical trials, and protein interaction assays
出版年份 2020 全文链接
标题
COVID‐19 drug repurposing: A review of computational screening methods, clinical trials, and protein interaction assays
作者
关键词
-
出版物
MEDICINAL RESEARCH REVIEWS
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-08-31
DOI
10.1002/med.21728
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
- (2020) Manli Wang et al. CELL RESEARCH
- Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
- (2020) Haibo Zhang et al. INTENSIVE CARE MEDICINE
- Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS
- (2020) Yushun Wan et al. JOURNAL OF VIROLOGY
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
- (2020) Canrong Wu et al. Acta Pharmaceutica Sinica B
- Probable Molecular Mechanism of Remdesivir for the Treatment of COVID-19: Need to Know More
- (2020) Abinit Saha et al. ARCHIVES OF MEDICAL RESEARCH
- Factors associated with prolonged viral shedding and impact of Lopinavir/Ritonavir treatment in hospitalised non-critically ill patients with SARS-CoV-2 infection
- (2020) Dan Yan et al. EUROPEAN RESPIRATORY JOURNAL
- The correlation between viral clearance and biochemical outcomes of 94 COVID-19 infected discharged patients
- (2020) Jing Yuan et al. INFLAMMATION RESEARCH
- Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection
- (2020) Jacques Fantini et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Prediction of Novel Inhibitors of the Main Protease (M-pro) of SARS-CoV-2 through Consensus Docking and Drug Reposition
- (2020) Aleix Gimeno et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency
- (2020) Calvin J. Gordon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study
- (2020) Sourav Das et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Peptide-like and small-molecule inhibitors against Covid-19
- (2020) Suyash Pant et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Identification of potential molecules against COVID-19 main protease through structure-guided virtual screening approach
- (2020) Lovika Mittal et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Potential anti-viral activity of approved repurposed drug against main protease of SARS-CoV-2: an in silico based approach
- (2020) Saurov Mahanta et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Repurposing approved drugs as inhibitors of SARS-CoV-2 S-protein from molecular modeling and virtual screening
- (2020) Osmair Vital de Oliveira et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19
- (2020) Nisha Muralidharan et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2
- (2020) Khattab Al-Khafaji et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes
- (2020) Ammar D. Elmezayen et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- In-silico approaches to detect inhibitors of the human severe acute respiratory syndrome coronavirus envelope protein ion channel
- (2020) Manoj Kumar Gupta et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Reverse vaccinology approach to design a novel multi-epitope vaccine candidate against COVID-19: an in silico study
- (2020) Maryam Enayatkhani et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Design of multi-epitope vaccine candidate against SARS-CoV-2: a in-silico study
- (2020) K. Abraham Peele et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Arbidol monotherapy is superior to lopinavir/ritonavir in treating COVID-19
- (2020) Zhen Zhu et al. JOURNAL OF INFECTION
- Arbidol combined with LPV/r versus LPV/r alone against Corona Virus Disease 2019: A retrospective cohort study
- (2020) Lisi Deng et al. JOURNAL OF INFECTION
- Tocilizumab treatment in COVID-19: A single center experience
- (2020) Pan Luo et al. JOURNAL OF MEDICAL VIROLOGY
- Conduction abnormalities in hydroxychloroquine add on therapy to lopinavir/ritonavir in COVID‐19
- (2020) Vui Heng Chong et al. JOURNAL OF MEDICAL VIROLOGY
- Letter to the Editor: Acute hypertriglyceridemia in patients with COVID‐19 receiving tocilizumab
- (2020) Austin R. Morrison et al. JOURNAL OF MEDICAL VIROLOGY
- Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
- (2020) Ivan Fan-Ngai Hung et al. LANCET
- Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
- (2020) Yeming Wang et al. LANCET
- Arbidol/IFN-α2b Therapy for Patients With Corona Virus Disease 2019: A Retrospective Multicenter Cohort Study
- (2020) Ping Xu et al. MICROBES AND INFECTION
- A human neutralizing antibody targets the receptor binding site of SARS-CoV-2
- (2020) Rui Shi et al. NATURE
- A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
- (2020) Bin Cao et al. NEW ENGLAND JOURNAL OF MEDICINE
- Compassionate Use of Remdesivir for Patients with Severe Covid-19
- (2020) Jonathan Grein et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structure of the RNA-dependent RNA polymerase from COVID-19 virus
- (2020) Yan Gao et al. SCIENCE
- In Silico Discovery of Candidate Drugs against Covid-19
- (2020) Claudia Cava et al. Viruses-Basel
- Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies
- (2020) Jianjun Gao et al. BioScience Trends
- A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease
- (2020) Donald C. Hall et al. Travel Medicine and Infectious Disease
- Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
- (2020) Philippe Gautret et al. Travel Medicine and Infectious Disease
- Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial
- (2020) Wei Tang et al. BMJ-British Medical Journal
- Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data
- (2020) Matthieu Mahévas et al. BMJ-British Medical Journal
- D3Targets-2019-nCoV: a webserver for predicting drug targets and for multi-target and multi-site based virtual screening against COVID-19
- (2020) Yulong Shi et al. Acta Pharmaceutica Sinica B
- Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
- (2020) Yadi Zhou et al. Cell Discovery
- Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study
- (2020) Qingxian Cai et al. Engineering
- High throughput and comprehensive approach to develop multiepitope vaccine against minacious COVID-19
- (2020) Rupal Ojha et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The pathogenesis and treatment of the `Cytokine Storm' in COVID-19
- (2020) Qing Ye et al. JOURNAL OF INFECTION
- Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
- (2020) Abdo A. Elfiky LIFE SCIENCES
- In silico studies on therapeutic agents for COVID-19: Drug repurposing approach
- (2020) Bhumi Shah et al. LIFE SCIENCES
- Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease
- (2020) Mahmoud Kandeel et al. LIFE SCIENCES
- No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection
- (2020) J.M. Molina et al. MEDECINE ET MALADIES INFECTIEUSES
- Compassionate remdesivir treatment of severe Covid-19 pneumonia in intensive care unit (ICU) and Non-ICU patients: Clinical outcome and differences in post-treatment hospitalisation status
- (2020) Spinello Antinori et al. PHARMACOLOGICAL RESEARCH
- Darunavir does not prevent SARS-CoV-2 infection in HIV patients
- (2020) Agostino Riva et al. PHARMACOLOGICAL RESEARCH
- Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
- (2020) Johanna Hansen et al. SCIENCE
- Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir
- (2019) Egor Tchesnokov et al. Viruses-Basel
- Adverse Effects of Dexamethasone in Surgical Patients
- (2019) Denise Blanchard et al. AMERICAN JOURNAL OF NURSING
- Darunavir for the treatment of HIV infection
- (2018) Vincenzo Spagnuolo et al. EXPERT OPINION ON PHARMACOTHERAPY
- Drug Repurposing for Viral Infectious Diseases: How Far Are We?
- (2018) Beatrice Mercorelli et al. TRENDS IN MICROBIOLOGY
- Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy
- (2018) Amber J. Giles et al. Journal for ImmunoTherapy of Cancer
- Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
- (2017) Timothy P. Sheahan et al. Science Translational Medicine
- Common and Rare Ocular Side-effects of the Dexamethasone Implant
- (2016) Janelle M. Fassbender Adeniran et al. OCULAR IMMUNOLOGY AND INFLAMMATION
- Lopinavir/ritonavir in the treatment of HIV-1 infection: a review
- (2016) Jonathan Shuter Therapeutics and Clinical Risk Management
- Arbidol as a broad-spectrum antiviral: An update
- (2014) Julie Blaising et al. ANTIVIRAL RESEARCH
- Does dexamethasone induce more neuropsychological side effects than prednisone in pediatric acute lymphoblastic leukemia? A systematic review
- (2014) L.T. Warris et al. PEDIATRIC BLOOD & CANCER
- Favipiravir (T-705), a novel viral RNA polymerase inhibitor
- (2013) Yousuke Furuta et al. ANTIVIRAL RESEARCH
- The value of drug repositioning in the current pharmaceutical market
- (2009) E.L. Tobinick DRUG NEWS & PERSPECTIVES
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