期刊
INFECTIOUS DISEASES NOW
卷 51, 期 3, 页码 228-235出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.medmal.2020.10.021
关键词
Infective endocarditis; Rothia; Rothia dentocariosa
RIE is a rare condition that primarily affects males, intravenous drug users, and immunocompetent individuals, with most cases caused by R. dentocariosa infection. Treatment often involves beta-lactam antibiotics and may require surgery. Overall prognosis appears to be favorable.
Objective: To describe the epidemiological, clinical, microbiological, and therapeutic features and outcomes of Rothia infective endocarditis (RIE) and extracardiac infections (ECRI). Methods: We performed a systematic literature review of published cases of RIE and ECRI. Results: After inclusion of a personal case report, 51 cases of RIE and 215 cases of ECRI were reported. Compared with ECRI patients, RIE patients were significantly more often males (80% versus 59%), intravenous drug users (IVDU) (20% versus 3%), immunocompetent (76% versus 31%), and infected with R. dentocariosa (55% versus 13%) but lacked significant differences with regard to median age (45 years [6-79]), rate of orodental abnormalities (33%), and six-month mortality (14%). Following microbiological documentation, RIE was most often treated with a beta-lactam antibiotic alone (39%) for a median duration of six weeks and required surgery in 39% of cases. Conclusion: RIE is rare and likely secondary to a dental portal of entry or cutaneous inoculation in IVDU. Its prognosis seems to be favorable. (C) 2020 Elsevier Masson SAS. All rights reserved.
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