A simple, cost‐effective, and rapid separation process for the isolation of anticoagulant active fraction from the fruit extract of Momordica charantia : Characterization of bioactive components and anticoagulant mechanism of active fraction in a mouse model

Anticoagulant mechanism, pharmacological activity, and assessment of preclinical safety of a novel fibrin(ogen)olytic serine protease from leaves of Leucas indica

(2018) Debananda Gogoi et al.   Scientific Reports

First Report of Plant-Derived β-Sitosterol with Antithrombotic, in Vivo Anticoagulant, and Thrombus-Preventing Activities in a Mouse Model

(2018) Debananda Gogoi et al.   JOURNAL OF NATURAL PRODUCTS

Role of heparin and non heparin binding serpins in coagulation and angiogenesis: A complex interplay

(2016) Teena Bhakuni et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

In Vivo Anticoagulant and Thrombolytic Activities of a Fibrinolytic Serine Protease (Brevithrombolase) With the k-Carrageenan-Induced Rat Tail Thrombosis Model

(2016) Sourav Majumdar et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Unraveling the Proteome Composition and Immuno-profiling of Western India Russell’s Viper Venom for In-Depth Understanding of Its Pharmacological Properties, Clinical Manifestations, and Effective Antivenom Treatment

(2016) Bhargab Kalita et al.   JOURNAL OF PROTEOME RESEARCH

Apoptosis induction in human breast cancer (MCF-7) cells by a novel venom l-amino acid oxidase (Rusvinoxidase) is independent of its enzymatic activity and is accompanied by caspase-7 activation and reactive oxygen species production

(2015) Ashis K. Mukherjee et al.   APOPTOSIS

Anticoagulant mechanism and platelet deaggregation property of a non-cytotoxic, acidic phospholipase A2 purified from Indian cobra (Naja naja) venom: Inhibition of anticoagulant activity by low molecular weight heparin

(2015) Sumita Dutta et al.   BIOCHIMIE

Momordica charantia seed extract exhibits strong anticoagulant effect by specifically interfering in intrinsic pathway of blood coagulation and dissolves fibrin clot

(2015) Bhagyalakshmi Manjappa et al.   BLOOD COAGULATION & FIBRINOLYSIS

Cardiovascular protective effect of glabridin: Implications in LDL oxidation and inflammation

(2015) Moo Rim Kang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Characterization, mechanism of anticoagulant action, and assessment of therapeutic potential of a fibrinolytic serine protease (Brevithrombolase) purified from Brevibacillus brevis strain FF02B

(2014) Sourav Majumdar et al.   BIOCHIMIE

A new peptide (Ruviprase) purified from the venom of Daboia russelii russelii shows potent anticoagulant activity via non-enzymatic inhibition of thrombin and factor Xa

(2014) Rupamoni Thakur et al.   BIOCHIMIE

Biochemical and pharmacological properties of a new thrombin-like serine protease (Russelobin) from the venom of Russell's Viper (Daboia russelii russelii) and assessment of its therapeutic potential

(2013) Ashis K. Mukherjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Thrombolytic, anticoagulant and antiplatelet activities of codiase, a bi-functional fibrinolytic enzyme from Codium fragile

(2013) Jun-Hui Choi et al.   BIOCHIMIE

Thrombolytic effects of Douchi Fibrinolytic enzyme from Bacillus subtilis LD-8547 in vitro and in vivo

(2012) Jun Yuan et al.   BMC BIOTECHNOLOGY

Oral Anticoagulant Therapy

(2012) Walter Ageno et al.   CHEST

Direct acting anti-thrombotic serine protease from brown seaweed Costaria costata

(2012) Dae-Won Kim et al.   PROCESS BIOCHEMISTRY

Identification of active compounds from medicinal plant extracts using gas chromatography-mass spectrometry and multivariate data analysis

(2011) Jianhong Ching et al.   JOURNAL OF SEPARATION SCIENCE

New oral anticoagulant drugs in cardiovascular disease

(2010) Gregory Lip et al.   THROMBOSIS AND HAEMOSTASIS