HY5-COP1: the central module of light signaling pathway

Light controls stamen elongation via cryptochromes, phytochromes and COP1 through HY5 and HYH

(2020) Davide Marzi et al.   PLANT JOURNAL

Time-Course Transcriptome Study Reveals Mode of bZIP Transcription Factors on Light Exposure in Arabidopsis

(2020) Yukio Kurihara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Light Activates Brassinosteroid Biosynthesis to Promote Hook Opening and Petiole Development in Arabidopsis thaliana

(2020) Hidefumi Hamasaki et al.   PLANT AND CELL PHYSIOLOGY

CONSTITUTIVELY PHOTOMORPHOGENIC1 promotes ABA‐mediated inhibition of post germination seedling establishment

(2020) Premachandran Yadukrishnan et al.   PLANT JOURNAL

COP1 destabilizes DELLA proteins in Arabidopsis

(2020) Noel Blanco-Touriñán et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryptochrome-mediated blue-light signalling modulates UVR8 photoreceptor activity and contributes to UV-B tolerance in Arabidopsis

(2020) Nicolas Tissot et al.   Nature Communications

Two E3 ligases antagonistically regulate the UV-B response inArabidopsis

(2019) Hui Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chloroplasts Modulate Elongation Responses to Canopy Shade by Retrograde Pathways Involving HY5 and Abscisic Acid

(2019) Miriam Ortiz-Alcaide et al.   PLANT CELL

Functional Interrelation of MYC 2 and HY 5 Plays an Important Role in Arabidopsis Seedling Development

(2019) Moumita Chakraborty et al.   PLANT JOURNAL

HY5 Interacts with the Histone Deacetylase HDA15 to Repress Hypocotyl Cell Elongation in Photomorphogenesis

(2019) Linmao Zhao et al.   PLANT PHYSIOLOGY

Beyond Light: Insights Into the Role of Constitutively Photomorphogenic1 in Plant Hormonal Signaling

(2019) Wenjing Wang et al.   Frontiers in Plant Science

Plant photoreceptors and their signaling components compete for COP 1 binding via VP peptide motifs

(2019) Kelvin Lau et al.   EMBO JOURNAL

Chloroplast development activates the expression of ascorbate biosynthesis-associated genes in Arabidopsis roots

(2019) Saki Shiroma et al.   PLANT SCIENCE

A phyB-PIF1-SPA1 kinase regulatory complex promotes photomorphogenesis in Arabidopsis

(2019) Inyup Paik et al.   Nature Communications

Molecular mechanisms underlying phytochrome-controlled morphogenesis in plants

(2019) Martina Legris et al.   Nature Communications

HY5 Contributes to Light-Regulated Root System Architecture Under a Root-Covered Culture System

(2019) Yonghong Zhang et al.   Frontiers in Plant Science

Cryptochrome 2 competes with COP1 substrates to repress COP1 ubiquitin ligase activity duringArabidopsisphotomorphogenesis

(2019) Jathish Ponnu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Light Control of Salt-Induced Proline Accumulation Is Mediated by ELONGATED HYPOCOTYL 5 in Arabidopsis

(2019) Hajnalka Kovács et al.   Frontiers in Plant Science

Photoreceptor-mediated regulation of the COP1/SPA E3 ubiquitin ligase

(2018) Roman Podolec et al.   CURRENT OPINION IN PLANT BIOLOGY

Low Temperature Enhanced Flavonol Synthesis Requires Light-Associated Regulatory Components in Arabidopsis thaliana

(2018) Chitra Bhatia et al.   PLANT AND CELL PHYSIOLOGY

Far-Red Light Detection in the Shoot Regulates Lateral Root Development through the HY5 Transcription Factor

(2018) Kasper van Gelderen et al.   PLANT CELL

Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains

(2018) Nikhil Job et al.   PLANT PHYSIOLOGY

COP1, a negative regulator of photomorphogenesis, positively regulates plant disease resistance via double-stranded RNA binding proteins

(2018) Gah-Hyun Lim et al.   PLoS Pathogens

ELONGATED HYPOCOTYL 5 mediates blue light signalling to the Arabidopsis circadian clock

(2018) Anita Hajdu et al.   PLANT JOURNAL

COP1 plays a prominent role in drought stress tolerance in Arabidopsis and Pea

(2018) Maryam Moazzam-Jazi et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Light-dependent suppression of COP1 multimeric complex formation is determined by the blue-light receptor FKF1 in Arabidopsis

(2018) Byoung-Doo Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Two B-Box Domain Proteins, BBX18 and BBX23, Interact with ELF3 and Regulate Thermomorphogenesis in Arabidopsis

(2018) Lan Ding et al.   Cell Reports

COP1 conveys warm temperature information to hypocotyl thermomorphogenesis

(2017) Young-Joon Park et al.   NEW PHYTOLOGIST

A CRY-BIC negative-feedback circuitry regulating blue light sensitivity of Arabidopsis

(2017) Xu Wang et al.   PLANT JOURNAL

A PIF1/PIF3-HY5-BBX23 Transcription Factor Cascade Affects Photomorphogenesis

(2017) Xinyu Zhang et al.   PLANT PHYSIOLOGY

OsbZIP48, a HY5 Transcription Factor Ortholog, Exerts Pleiotropic Effects in Light-Regulated Development

(2017) Naini Burman et al.   PLANT PHYSIOLOGY

Phosphorylation and negative regulation of CONSTITUTIVELY PHOTOMORPHOGENIC 1 by PINOIDin Arabidopsis

(2017) Fang Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncanonical role ofArabidopsisCOP1/SPA complex in repressing BIN2-mediated PIF3 phosphorylation and degradation in darkness

(2017) Jun-Jie Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HY5, a positive regulator of light signaling, negatively controls the unfolded protein response inArabidopsis

(2017) Ganesh M. Nawkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The F-box protein FKF1 inhibits dimerization of COP1 in the control of photoperiodic flowering

(2017) Byoung-Doo Lee et al.   Nature Communications

DET1 and HY5 Control PIF4-Mediated Thermosensory Elongation Growth through Distinct Mechanisms

(2017) Sreeramaiah N. Gangappa et al.   Cell Reports

High Ambient Temperature Represses Anthocyanin Biosynthesis through Degradation of HY5

(2017) Sara Kim et al.   Frontiers in Plant Science

FAR-RED INSENSITIVE 219/JAR1 Contributes to Shade Avoidance Responses of Arabidopsis Seedlings by Modulating Key Shade Signaling Components

(2017) Swadhin Swain et al.   Frontiers in Plant Science

Seedlings Transduce the Depth and Mechanical Pressure of Covering Soil Using COP1 and Ethylene to Regulate EBF1/EBF2 for Soil Emergence

(2016) Hui Shi et al.   CURRENT BIOLOGY

Shoot-to-Root Mobile Transcription Factor HY5 Coordinates Plant Carbon and Nitrogen Acquisition

(2016) Xiangbin Chen et al.   CURRENT BIOLOGY

BZR1 Interacts with HY5 to Mediate Brassinosteroid- and Light-Regulated Cotyledon Opening in Arabidopsis in Darkness

(2016) Qian-Feng Li et al.   Molecular Plant

The Multifaceted Roles of HY5 in Plant Growth and Development

(2016) Sreeramaiah N. Gangappa et al.   Molecular Plant

Convergence of CONSTITUTIVE PHOTOMORPHOGENESIS 1 and PHYTOCHROME INTERACTING FACTOR signalling during shade avoidance

(2016) Manuel Pacín et al.   NEW PHYTOLOGIST

Salt Stress and Ethylene Antagonistically Regulate Nucleocytoplasmic Partitioning of COP1 to Control Seed Germination

(2016) Yanwen Yu et al.   PLANT PHYSIOLOGY

BBX21, anArabidopsisB-box protein, directly activatesHY5and is targeted by COP1 for 26S proteasome-mediated degradation

(2016) Dongqing Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Light affects salt stress-induced transcriptional memory ofP5CS1inArabidopsis

(2016) Xuan Jun Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem-piped light activates phytochrome B to trigger light responses in Arabidopsis thaliana roots

(2016) H.-J. Lee et al.   Science Signaling

Structural Basis for Substrate Selectivity of the E3 Ligase COP1

(2016) Sacha Uljon et al.   STRUCTURE

An Arabidopsis SUMO E3 Ligase, SIZ1, Negatively Regulates Photomorphogenesis by Promoting COP1 Activity

(2016) Xiao-Li Lin et al.   PLoS Genetics

COP1 Controls Abiotic Stress Responses by Modulating AtSIZ1 Function through Its E3 Ubiquitin Ligase Activity

(2016) Joo Y. Kim et al.   Frontiers in Plant Science

Stem-piped light activates phytochrome B to trigger light responses in Arabidopsis thaliana roots

(2016) H.-J. Lee et al.   Science Signaling

Red-Light-Dependent Interaction of phyB with SPA1 Promotes COP1–SPA1 Dissociation and Photomorphogenic Development in Arabidopsis

(2015) Xue-Dan Lu et al.   Molecular Plant

Integrating circadian dynamics with physiological processes in plants

(2015) Kathleen Greenham et al.   NATURE REVIEWS GENETICS

The Transcriptional Regulator BBX19 Promotes Hypocotyl Growth by Facilitating COP1-Mediated EARLY FLOWERING3 Degradation in Arabidopsis

(2015) Chang-Quan Wang et al.   PLANT CELL

Two Distinct Domains of the UVR8 Photoreceptor Interact with COP1 to Initiate UV-B Signaling in Arabidopsis

(2015) Ruohe Yin et al.   PLANT CELL

Light-Activated Phytochrome A and B Interact with Members of the SPA Family to Promote Photomorphogenesis in Arabidopsis by Reorganizing the COP1/SPA Complex

(2015) David J. Sheerin et al.   PLANT CELL

High-level expression and phosphorylation of phytochrome B modulates flowering time in Arabidopsis

(2015) Anita Hajdu et al.   PLANT JOURNAL

SHW1 Interacts with HY5 and COP1, and Promotes COP1-mediated Degradation of HY5 During Arabidopsis Seedling Development

(2015) Anjil Kumar Srivastava et al.   PLANT PHYSIOLOGY

Regulation of carotenoid biosynthesis by shade relies on specific subsets of antagonistic transcription factors and co-factors

(2015) Jordi Bou-Torrent et al.   PLANT PHYSIOLOGY

The E3 Ubiquitin Ligase COP1 Regulates Thermosensory Flowering by Triggering GI Degradation in Arabidopsis

(2015) Kiyoung Jang et al.   Scientific Reports

LSD1 and HY5 antagonistically regulate red light induced-programmed cell death in Arabidopsis

(2015) Tingting Chai et al.   Frontiers in Plant Science

Functional analysis of COP1 and SPA orthologs from Physcomitrella and rice during photomorphogenesis of transgenic Arabidopsis reveals distinct evolutionary conservation

(2014) Aashish Ranjan et al.   BMC PLANT BIOLOGY

Repression of Jasmonate-Dependent Defenses by Shade Involves Differential Regulation of Protein Stability of MYC Transcription Factors and Their JAZ Repressors in Arabidopsis

(2014) J.-M. Chico et al.   PLANT CELL

ArabidopsisCAM7 and HY5 Physically Interact and Directly Bind to theHY5Promoter to Regulate Its Expression and Thereby Promote Photomorphogenesis

(2014) Nazia Abbas et al.   PLANT CELL

The RING-Finger E3 Ubiquitin Ligase COP1 SUPPRESSOR1 Negatively Regulates COP1 Abundance in Maintaining COP1 Homeostasis in Dark-Grown Arabidopsis Seedlings

(2014) D. Xu et al.   PLANT CELL

UV-B-Responsive Association of the Arabidopsis bZIP Transcription Factor ELONGATED HYPOCOTYL5 with Target Genes, Including Its Own Promoter

(2014) M. Binkert et al.   PLANT CELL

Darkness andgulliver2/phyBmutation decrease the abundance of phosphorylated BZR1 to activate brassinosteroid signaling in Arabidopsis

(2014) Bokyung Kim et al.   PLANT JOURNAL

Rapid Decline in Nuclear COSTITUTIVE PHOTOMORPHOGENESIS1 Abundance Anticipates the Stabilization of Its Target ELONGATED HYPOCOTYL5 in the Light

(2014) M. Pacin et al.   PLANT PHYSIOLOGY

Differential Accumulation of ELONGATED HYPOCOTYL5 Correlates with Hypocotyl Bending to Ultraviolet-B Light

(2014) Filip Vandenbussche et al.   PLANT PHYSIOLOGY

Arabidopsis cell expansion is controlled by a photothermal switch

(2014) Henrik Johansson et al.   Nature Communications

The DET1-COP1-HY5 Pathway Constitutes a Multipurpose Signaling Module Regulating Plant Photomorphogenesis and Thermomorphogenesis

(2014) Carolin Delker et al.   Cell Reports

Convergence of Light and ABA Signaling on the ABI5 Promoter

(2014) Dongqing Xu et al.   PLoS Genetics

The HY5-PIF Regulatory Module Coordinates Light and Temperature Control of Photosynthetic Gene Transcription

(2014) Gabriela Toledo-Ortiz et al.   PLoS Genetics

Photoreceptor Signaling Networks in Plant Responses to Shade

(2013) Jorge J. Casal   Annual Review of Plant Biology

Three Transcription Factors, HFR1, LAF1 and HY5, Regulate Largely Independent Signaling Pathways Downstream of Phytochrome A

(2013) In-Cheol Jang et al.   PLANT AND CELL PHYSIOLOGY

The Arabidopsis B-BOX Protein BBX25 Interacts with HY5, Negatively Regulating BBX22 Expression to Suppress Seedling Photomorphogenesis

(2013) S. N. Gangappa et al.   PLANT CELL

Heat Shock-Induced Fluctuations in Clock and Light Signaling Enhance Phytochrome B-Mediated Arabidopsis Deetiolation

(2013) E. Karayekov et al.   PLANT CELL

ArabidopsisPhytochrome B Promotes SPA1 Nuclear Accumulation to Repress Photomorphogenesis under Far-Red Light

(2013) Xu Zheng et al.   PLANT CELL

Antagonistic Basic Helix-Loop-Helix/bZIP Transcription Factors Form Transcriptional Modules That Integrate Light and Reactive Oxygen Species Signaling inArabidopsis

(2013) Dongqin Chen et al.   PLANT CELL

COP1 re-accumulates in the nucleus under shade

(2013) Manuel Pacín et al.   PLANT JOURNAL

Dynamics of the Shade-Avoidance Response in Arabidopsis

(2013) A. Ciolfi et al.   PLANT PHYSIOLOGY

Reversion of the Arabidopsis UV-B photoreceptor UVR8 to the homodimeric ground state

(2013) M. Heijde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis STO/BBX24 negatively regulates UV-B signaling by interacting with COP1 and repressing HY5 transcriptional activity

(2012) Lei Jiang et al.   CELL RESEARCH

COP1 mediates the coordination of root and shoot growth by light through modulation of PIN1- and PIN2-dependent auxin transport in Arabidopsis

(2012) M. Sassi et al.   DEVELOPMENT

Linking photoreceptor excitation to changes in plant architecture

(2012) L. Li et al.   GENES & DEVELOPMENT

Molecular Interactions of GBF1 with HY5 and HYH Proteins during Light-mediated Seedling Development inArabidopsis thaliana

(2012) Aparna Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Root Greening by Light and Auxin/Cytokinin Signaling in Arabidopsis

(2012) K. Kobayashi et al.   PLANT CELL

Arabidopsis FHY3 and HY5 Positively Mediate Induction of COP1 Transcription in Response to Photomorphogenic UV-B Light

(2012) X. Huang et al.   PLANT CELL

EARLY FLOWERING4 Recruitment of EARLY FLOWERING3 in the Nucleus Sustains the Arabidopsis Circadian Clock

(2012) E. Herrero et al.   PLANT CELL

Phytochrome interacting factors 4 and 5 control seedling growth in changing light conditions by directly controlling auxin signaling

(2012) Patricia Hornitschek et al.   PLANT JOURNAL

Arabidopsis COP1 and SPA Genes Are Essential for Plant Elongation But Not for Acceleration of Flowering Time in Response to a Low Red Light to Far-Red Light Ratio

(2012) S. Rolauffs et al.   PLANT PHYSIOLOGY

MdCOP1 Ubiquitin E3 Ligases Interact with MdMYB1 to Regulate Light-Induced Anthocyanin Biosynthesis and Red Fruit Coloration in Apple

(2012) Y.-Y. Li et al.   PLANT PHYSIOLOGY

The photomorphogenic repressors COP1 and DET1: 20 years later

(2012) On Sun Lau et al.   TRENDS IN PLANT SCIENCE

Functional Characterization of HY5 Homolog Genes Involved in Early Light-Signaling inPhyscomitrella patens

(2011) Saori YAMAWAKI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Blue Light-Dependent Interaction of CRY2 with SPA1 Regulates COP1 activity and Floral Initiation in Arabidopsis

(2011) Zecheng Zuo et al.   CURRENT BIOLOGY

Arabidopsis cryptochrome 1 interacts with SPA1 to suppress COP1 activity in response to blue light

(2011) B. Liu et al.   GENES & DEVELOPMENT

Blue-light-dependent interaction of cryptochrome 1 with SPA1 defines a dynamic signaling mechanism

(2011) H.-L. Lian et al.   GENES & DEVELOPMENT

Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis

(2011) Gang Li et al.   NATURE CELL BIOLOGY

TheCOP1OrthologPPSRegulates the Juvenile–Adult and Vegetative–Reproductive Phase Changes in Rice

(2011) Nobuhiro Tanaka et al.   PLANT CELL

Repression of shade-avoidance reactions by sunfleck induction of HY5 expression in Arabidopsis

(2011) Romina Sellaro et al.   PLANT JOURNAL

COP1-Mediated Degradation of BBX22/LZF1 Optimizes Seedling Development in Arabidopsis

(2011) C.-S. J. Chang et al.   PLANT PHYSIOLOGY

Integration of low temperature and light signaling during cold acclimation response in Arabidopsis

(2011) R. Catala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arabidopsis PHYTOCHROME INTERACTING FACTOR Proteins Promote Phytochrome B Polyubiquitination by COP1 E3 Ligase in the Nucleus

(2010) I.-C. Jang et al.   PLANT CELL

Arabidopsis Transcription Factor ELONGATED HYPOCOTYL5 Plays a Role in the Feedback Regulation of Phytochrome A Signaling

(2010) J. Li et al.   PLANT CELL

Genome-wide mapping of the HY5-mediated genenetworks in Arabidopsis that involve both transcriptional and post-transcriptional regulation

(2010) Huiyong Zhang et al.   PLANT JOURNAL

Light signal transduction: an infinite spectrum of possibilities

(2010) Joanne Chory   PLANT JOURNAL

AtBBX21 and COP1 genetically interact in the regulation of shade avoidance

(2010) Carlos D. Crocco et al.   PLANT JOURNAL

Cryptochrome 2 and phototropin 2 regulate resistance protein-mediated viral defense by negatively regulating an E3 ubiquitin ligase

(2010) R.-D. Jeong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Negative feedback regulation of UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis

(2010) H. Gruber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Light Regulation of Gibberellin Biosynthesis in Pea Is Mediated through the COP1/HY5 Pathway

(2009) J. L. Weller et al.   PLANT CELL

FAR-RED ELONGATED HYPOCOTYL1 and FHY1-LIKE Associate with the Arabidopsis Transcription Factors LAF1 and HFR1 to Transmit Phytochrome A Signals for Inhibition of Hypocotyl Elongation

(2009) S. W. Yang et al.   PLANT CELL

Arabidopsis COP1 shapes the temporal pattern of CO accumulation conferring a photoperiodic flowering response

(2008) Seonghoe Jang et al.   EMBO JOURNAL

GBF1, a Transcription Factor of Blue Light Signaling inArabidopsis, Is Degraded in the Dark by a Proteasome-mediated Pathway Independent of COP1 and SPA1

(2008) Chandrashekara Mallappa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

COP1 and ELF3 Control Circadian Function and Photoperiodic Flowering by Regulating GI Stability

(2008) Jae-Woong Yu et al.   MOLECULAR CELL

LZF1/SALT TOLERANCE HOMOLOG3, an Arabidopsis B-Box Protein Involved in Light-Dependent Development and Gene Expression, Undergoes COP1-Mediated Ubiquitination

(2008) S. Datta et al.   PLANT CELL

Biochemical Characterization of Arabidopsis Complexes Containing CONSTITUTIVELY PHOTOMORPHOGENIC1 and SUPPRESSOR OF PHYA Proteins in Light Control of Plant Development

(2008) D. Zhu et al.   PLANT CELL

COP1-Mediated Ubiquitination of CONSTANS Is Implicated in Cryptochrome Regulation of Flowering in Arabidopsis

(2008) L.-J. Liu et al.   PLANT CELL

Light Plays an Essential Role in Intracellular Distribution of Auxin Efflux Carrier PIN2 in Arabidopsis thaliana

(2008) Ashverya Laxmi et al.   PLoS One

The Clock Protein CCA1 and the bZIP Transcription Factor HY5 Physically Interact to Regulate Gene Expression in Arabidopsis

(2007) Christos Andronis et al.   Molecular Plant