Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity

The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

(2019) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Characterization of Blimp-1 function in effector regulatory T cells

(2018) Erika Cretney et al.   JOURNAL OF AUTOIMMUNITY

Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1

(2018) Aline Yen Ling Wang et al.   MOLECULAR IMMUNOLOGY

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation

(2018) Xiaoyan Yu et al.   Nature Communications

Ubc9Is Required for Positive Selection and Late-Stage Maturation of Thymocytes

(2017) Aibo Wang et al.   JOURNAL OF IMMUNOLOGY

NFATc1 controls the cytotoxicity of CD8+ T cells

(2017) Stefan Klein-Hessling et al.   Nature Communications

Cytotoxic CD4 T Cells—Friend or Foe during Viral Infection?

(2017) Jennifer A. Juno et al.   Frontiers in Immunology

Selective Impairment of TH17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T Lymphocytes

(2016) Marcos Iglesias et al.   PLoS One

Protein SUMOylation Is Required for Regulatory T Cell Expansion and Function

(2016) Xiao Ding et al.   Cell Reports

NFAT1 deficit and NFAT2 deficit attenuate EAE via different mechanisms

(2015) Lena Dietz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells

(2015) Gustavo J. Martinez et al.   IMMUNITY

CD4 memory T cells develop and acquire functional competence by sequential cognate interactions and stepwise gene regulation

(2015) Tomohiro Kaji et al.   INTERNATIONAL IMMUNOLOGY

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

(2015) Adrien Decque et al.   NATURE IMMUNOLOGY

Selective NFAT targeting in T cells ameliorates GvHD while maintaining antitumor activity

(2015) Martin Vaeth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses

(2014) Nicole Joller et al.   IMMUNITY

Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool

(2014) J. Christoph Vahl et al.   IMMUNITY

Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression

(2014) Martin Vaeth et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blimp-1 Attenuates Th1 Differentiation by Repression of ifng, tbx21, and bcl6 Gene Expression

(2014) L. Cimmino et al.   JOURNAL OF IMMUNOLOGY

Continuous requirement for the TCR in regulatory T cell function

(2014) Andrew G Levine et al.   NATURE IMMUNOLOGY

Characterisation of a novel A1-specific monoclonal antibody

(2014) M J Lang et al.   Cell Death & Disease

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity

(2013) Dmitri Lodygin et al.   NATURE MEDICINE

NFATc1/αA: The other Face of NFAT Factors in Lymphocytes

(2012) Edgar Serfling et al.   Cell Communication and Signaling

SUMO-Specific Protease 1 Is Critical for Early Lymphoid Development through Regulation of STAT5 Activation

(2012) Thang Van Nguyen et al.   MOLECULAR CELL

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells

(2012) M. Vaeth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The many faces of Th17 cells

(2011) Anneli Peters et al.   CURRENT OPINION IN IMMUNOLOGY

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells

(2010) Maria H. Lexberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Control of Regulatory T Cell Lineage Commitment and Maintenance

(2009) Steven Z. Josefowicz et al.   IMMUNITY

Sumoylation of the Transcription Factor NFATc1 Leads to Its Subnuclear Relocalization and Interleukin-2 Repression by Histone Deacetylase

(2009) Arnab Nayak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blimp-1Δexon7: A naturally occurring Blimp-1 deletion mutant with auto-regulatory potential

(2008) Doris Schmidt et al.   EXPERIMENTAL CELL RESEARCH

Blimp-1 directly repressesIl2and theIl2activatorFos, attenuating T cell proliferation and survival

(2008) Gislâine A. Martins et al.   JOURNAL OF EXPERIMENTAL MEDICINE