Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma

B cells are associated with survival and immunotherapy response in sarcoma

(2020) Florent Petitprez et al.   NATURE

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

(2020) Rita Cabrita et al.   NATURE

B cells and tertiary lymphoid structures promote immunotherapy response

(2020) Beth A. Helmink et al.   NATURE

A Randomized Double-Blind Placebo-Controlled Phase 2 Trial Of Dendritic Cell Vaccine ICT-107 In Newly Diagnosed Patients With Glioblastoma

(2019) Patrick Y. Wen et al.   CLINICAL CANCER RESEARCH

Elevated numbers of PD-L1 expressing B cells are associated with the development of AIDS-NHL

(2019) Marta Epeldegui et al.   Scientific Reports

Myeloid-derived suppressive cells promote B cell-mediated immunosuppression via transfer of PD-L1 in glioblastoma

(2019) Catalina Lee-Chang et al.   Cancer Immunology Research

Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma

(2019) Peng Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma

(2018) Katarzyna C. Pituch et al.   MOLECULAR THERAPY

Cancer-mutation network and the number and specificity of driver mutations

(2018) Jaime Iranzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma

(2018) Martin J. B. Taphoorn et al.   JAMA Oncology

CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature

(2018) Antoine Louveau et al.   NATURE NEUROSCIENCE

Dendritic cell vaccines for high-grade gliomas

(2018) Matthew Eagles et al.   Therapeutics and Clinical Risk Management

Dendritic Cells and CD8 T Cell Immunity in Tumor Microenvironment

(2018) Chunmei Fu et al.   Frontiers in Immunology

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

(2017) Roger Stupp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial

(2017) Michael Weller et al.   LANCET ONCOLOGY

Characterization of human FCRL4-positive B cells

(2017) Michel Jourdan et al.   PLoS One

Antigen-Presenting Intratumoral B Cells Affect CD4 + TIL Phenotypes in Non–Small Cell Lung Cancer Patients

(2017) Tullia C. Bruno et al.   Cancer Immunology Research

Using Antigen-Specific B Cells to Combine Antibody and T Cell–Based Cancer Immunotherapy

(2017) Kerstin Wennhold et al.   Cancer Immunology Research

Anti-GITR therapy promotes immunity against malignant glioma in a murine model

(2016) Jason Miska et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Serum elevation of B lymphocyte stimulator does not increase regulatory B cells in glioblastoma patients undergoing immunotherapy

(2016) Anirudh Saraswathula et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Emerging Role of B Cells in Tumor Immunity

(2016) Peiling Tsou et al.   CANCER RESEARCH

Aging Converts Innate B1a Cells into Potent CD8+T Cell Inducers

(2016) Catalina Lee-Chang et al.   JOURNAL OF IMMUNOLOGY

Diversity and divergence of the glioma-infiltrating T-cell receptor repertoire

(2016) Jennifer S. Sims et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PD-L1 is a critical mediator of regulatory B cells and T cells in invasive breast cancer

(2016) Honggeng Guan et al.   Scientific Reports

Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells

(2015) M. Bodogai et al.   CANCER RESEARCH

Survival in Patients With Severe Lymphopenia Following Treatment With Radiation and Chemotherapy for Newly Diagnosed Solid Tumors

(2015) Stuart A. Grossman et al.   Journal of the National Comprehensive Cancer Network

In vitroandin vivoimaging of initial B-T-cell interactions in the setting of B-cell based cancer immunotherapy

(2015) Nela Klein Gonzalez et al.   OncoImmunology

Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity

(2014) C. Lee-Chang et al.   BLOOD

Sustained CD4+T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide

(2014) Susannah Ellsworth et al.   OncoImmunology

BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide

(2013) Luis Sanchez-Perez et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Enhanced antitumor immunotherapeutic effect of B-cell-based vaccine transduced with modified adenoviral vector containing type 35 fiber structures

(2013) E-K Kim et al.   GENE THERAPY

Comparison of Glioma-associated Antigen Peptide-loaded Versus Autologous Tumor Lysate-loaded Dendritic Cell Vaccination in Malignant Glioma Patients

(2013) Robert M. Prins et al.   JOURNAL OF IMMUNOTHERAPY

IDO Expression in Brain Tumors Increases the Recruitment of Regulatory T Cells and Negatively Impacts Survival

(2012) D. A. Wainwright et al.   CLINICAL CANCER RESEARCH

CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27- Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer

(2012) J. S. Nielsen et al.   CLINICAL CANCER RESEARCH

B-Cell Cross-Presentation of Autologous Antigen Precipitates Diabetes

(2012) E. Marino et al.   DIABETES

Recent developments on immunotherapy for brain cancer

(2012) Derek A Wainwright et al.   EXPERT OPINION ON EMERGING DRUGS

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

Immunosuppression in Patients with High-Grade Gliomas Treated with Radiation and Temozolomide

(2011) Stuart A. Grossman et al.   CLINICAL CANCER RESEARCH

Phase I trial of sorafenib in patients with recurrent or progressive malignant glioma

(2011) L. B. Nabors et al.   NEURO-ONCOLOGY

Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma

(2011) B. Raychaudhuri et al.   NEURO-ONCOLOGY

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Combating immunosuppression in glioma

(2008) Eleanor A Vega et al.   Future Oncology

CD40 Ligand-activated, antigen-specific B cells are comparable to mature dendritic cells in presenting protein antigens and major histocompatibility complex class I- and class II-binding peptides

(2008) Tahamtan Ahmadi et al.   IMMUNOLOGY