p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease
出版年份 2020 全文链接
标题
p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 130, Issue 9, Pages 5011-5026
出版商
American Society for Clinical Investigation
发表日期
2020-08-17
DOI
10.1172/jci135536
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Epigenetics and epigenomics in diabetic kidney disease and metabolic memory
- (2019) Mitsuo Kato et al. Nature Reviews Nephrology
- MicroRNA-214 promotes chronic kidney disease by disrupting mitochondrial oxidative phosphorylation
- (2019) Mi Bai et al. KIDNEY INTERNATIONAL
- Erianin protects against high glucose-induced oxidative injury in renal tubular epithelial cells
- (2019) Mei-Fen Chen et al. FOOD AND CHEMICAL TOXICOLOGY
- Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes
- (2019) Shinsuke Sakai et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy
- (2018) Qian Lu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury
- (2018) Qingqing Wei et al. JOURNAL OF CLINICAL INVESTIGATION
- P53 in kidney injury and repair: Mechanism and therapeutic potentials
- (2018) Chengyuan Tang et al. PHARMACOLOGY & THERAPEUTICS
- Modelling diabetic nephropathy in mice
- (2017) Kengo Azushima et al. Nature Reviews Nephrology
- Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction
- (2016) Man J. Livingston et al. Autophagy
- A very-low-protein diet ameliorates advanced diabetic nephropathy through autophagy induction by suppression of the mTORC1 pathway in Wistar fatty rats, an animal model of type 2 diabetes and obesity
- (2016) Munehiro Kitada et al. DIABETOLOGIA
- Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy
- (2015) Atsuko Tagawa et al. DIABETES
- Mitochondrial Hormesis and Diabetic Complications: Figure 1
- (2015) Kumar Sharma DIABETES
- Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy
- (2015) Wei Jing Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The renoprotective role of autophagy activation in proximal tubular epithelial cells in diabetic nephropathy
- (2015) Ying Xu et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury
- (2015) K. Bhatt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- DSePA Antagonizes High Glucose-Induced Neurotoxicity: Evidences for DNA Damage-Mediated p53 Phosphorylation and MAPKs and AKT Pathways
- (2015) Kun Wang et al. MOLECULAR NEUROBIOLOGY
- New Insights Into Molecular Mechanisms of Diabetic Kidney Disease
- (2014) Shawn S. Badal et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Molecular mechanisms of diabetic kidney disease
- (2014) Kimberly Reidy et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy in diabetic nephropathy
- (2014) Yan Ding et al. JOURNAL OF ENDOCRINOLOGY
- Tubular p53 Regulates Multiple Genes to Mediate AKI
- (2014) D. Zhang et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Diabetic nephropathy—emerging epigenetic mechanisms
- (2014) Mitsuo Kato et al. Nature Reviews Nephrology
- MicroRNAs in kidney physiology and disease
- (2014) Piera Trionfini et al. Nature Reviews Nephrology
- Transforming Growth Factor-β–Induced Cross Talk Between p53 and a MicroRNA in the Pathogenesis of Diabetic Nephropathy
- (2013) Supriya D. Deshpande et al. DIABETES
- New Autophagy Reporter Mice Reveal Dynamics of Proximal Tubular Autophagy
- (2013) L. Li et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- MicroRNA-214 Antagonism Protects against Renal Fibrosis
- (2013) L. Denby et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Obesity-Mediated Autophagy Insufficiency Exacerbates Proteinuria-induced Tubulointerstitial Lesions
- (2013) K. Yamahara et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
- (2013) Francesca Nazio et al. NATURE CELL BIOLOGY
- Autophagy Attenuates Diabetic Glomerular Damage through Protection of Hyperglycemia-Induced Podocyte Injury
- (2013) Li Fang et al. PLoS One
- MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death
- (2012) Arin B. Aurora et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy
- (2012) S. Putta et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Autophagy in proximal tubules protects against acute kidney injury
- (2012) Man Jiang et al. KIDNEY INTERNATIONAL
- The pathogenic role of the renal proximal tubular cell in diabetic nephropathy
- (2012) S. C. W. Tang et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Can We Target Tubular Damage to Prevent Renal Function Decline in Diabetes?
- (2012) Joseph V. Bonventre SEMINARS IN NEPHROLOGY
- A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy
- (2011) Yashpal S. Kanwar et al. Annual Review of Pathology-Mechanisms of Disease
- Renal Function in Diabetic Disease Models: The Tubular System in the Pathophysiology of the Diabetic Kidney
- (2011) Volker Vallon et al. Annual Review of Physiology
- Diabetes Complications: The MicroRNA Perspective
- (2011) P. Kantharidis et al. DIABETES
- Nutrient Sensing, Autophagy, and Diabetic Nephropathy
- (2011) S. Kume et al. DIABETES
- Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes
- (2011) Munehiro Kitada et al. Experimental Diabetes Research
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- The role of the Atg1/ULK1 complex in autophagy regulation
- (2010) Noboru Mizushima CURRENT OPINION IN CELL BIOLOGY
- Autophagy regulation by p53
- (2010) Maria Chiara Maiuri et al. CURRENT OPINION IN CELL BIOLOGY
- AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes
- (2010) Assaad A. Eid et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pathologic Classification of Diabetic Nephropathy
- (2010) T. W. C. Tervaert et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Large kidneys predict poor renal outcome in subjects with diabetes and chronic kidney disease
- (2010) Vincent Rigalleau et al. BMC Nephrology
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
- (2009) Ian G. Ganley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mouse Models of Diabetic Nephropathy
- (2009) F. C. Brosius et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
- (2009) Chang Hwa Jung et al. MOLECULAR BIOLOGY OF THE CELL
- FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
- (2008) Taichi Hara et al. JOURNAL OF CELL BIOLOGY
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- A complex barcode underlies the heterogeneous response of p53 to stress
- (2008) Fiona Murray-Zmijewski et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation