BDNF promoted osteoblast migration and fracture healing by up‐regulating integrin β1 via TrkB‐mediated ERK1/2 and AKT signalling

Brain-derived neurotrophic factor induces thioredoxin-1 expression through TrkB/Akt/CREB pathway in SH-SY5Y cells

(2019) Liping Bai et al.   BIOCHIMIE

TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Corpus Callosum

(2019) Huynh T. H. Nguyen et al.   Frontiers in Molecular Neuroscience

Effects of new beta-type Ti-40Nb implant materials, brain-derived neurotrophic factor, acetylcholine and nicotine on human mesenchymal stem cells of osteoporotic and non osteoporotic donors

(2018) Vivien Kauschke et al.   PLoS One

β1 integrins mediate the BMP2 dependent transcriptional control of osteoblast differentiation and osteogenesis

(2018) Molly Brunner et al.   PLoS One

Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library

(2018) Spyros Merkouris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Brain-Derived Neurotrophic Factor on the Neurogenesis and Osteogenesis in Bone Engineering

(2018) Qing Liu et al.   TISSUE ENGINEERING PART A

Mesenchymal Stem Cell Migration during Bone Formation and Bone Diseases Therapy

(2018) Peihong Su et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recombinant growth differentiation factor 11 impairs fracture healing through inhibiting chondrocyte differentiation

(2018) Rixin Zheng et al.   Annals of the New York Academy of Sciences

Effects of a Pasty Bone Cement Containing Brain-Derived Neurotrophic Factor-Functionalized Mesoporous Bioactive Glass Particles on Metaphyseal Healing in a New Murine Osteoporotic Fracture Model

(2018) Vivien Kauschke et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

BDNF regulates the expression and secretion of VEGF from osteoblasts via the TrkB/ERK1/2 signaling pathway during fracture healing

(2017) Zitao Zhang et al.   Molecular Medicine Reports

Granulocyte colony-stimulating factor (G-CSF) upregulates β1 integrin and increases migration of human trophoblast Swan 71 cells via PI3K and MAPK activation

(2016) Verónica A. Furmento et al.   EXPERIMENTAL CELL RESEARCH

Effect on Clinical Outcome and Growth Factor Synthesis With Adjunctive Use of Pulsed Electromagnetic Fields for Fifth Metatarsal Nonunion Fracture

(2016) Adam Streit et al.   FOOT & ANKLE INTERNATIONAL

7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders

(2016) Chaoyang Liu et al.   Translational Neurodegeneration

Brain-derived neurotrophic factor and its clinical implications

(2015) Siresha Bathina et al.   Archives of Medical Science

Brain-derived neurotrophic factor regulates cell motility in human colon cancer

(2015) S.-M. Huang et al.   ENDOCRINE-RELATED CANCER

Osteoblast recruitment to sites of bone formation in skeletal development, homeostasis, and regeneration

(2015) Naomi Dirckx et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

BDNF and its TrkB receptor in human fracture healing

(2014) Olaf Kilian et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

The effect of conditional inactivation of beta 1 integrins using twist 2 Cre, Osterix Cre and osteocalcin Cre lines on skeletal phenotype

(2014) Asha Shekaran et al.   BONE

Mature osteoblasts dedifferentiate in response to traumatic bone injury in the zebrafish fin and skull

(2014) K. Geurtzen et al.   DEVELOPMENT

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

G-protein-coupled receptor kinase interactor-1 serine 419 accelerates premature synapse formation in cortical neurons by interacting with Ca(2+)/calmodulin-dependent protein kinase IIβ

(2013) Zitao Zhang et al.   BRAIN RESEARCH BULLETIN

Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease

(2013) Frank M. Longo et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting integrins to promote bone formation and repair

(2013) Pierre J. Marie   Nature Reviews Endocrinology

β5 Integrin Up-Regulation in Brain-Derived Neurotrophic Factor Promotes Cell Motility in Human Chondrosarcoma

(2013) Chih-Yang Lin et al.   PLoS One

Optimal Intensity Shock Wave Promotes the Adhesion and Migration of Rat Osteoblasts via Integrin β1-mediated Expression of Phosphorylated Focal Adhesion Kinase

(2012) Jian-kun Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BDNF-mediated migration of cardiac microvascular endothelial cells is impaired during ageing

(2012) Liang Cao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The release of glutamate from cortical neurons regulated by BDNF via the TrkB/Src/PLC-γ1 pathway

(2012) Zitao Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cooperation Between Integrins and Growth Factor Receptors in Signaling and Endocytosis

(2011) Johanna Ivaska et al.   Annual Review of Cell and Developmental Biology

Brain-derived neurotrophic factor induces migration of endothelial cells through a TrkB-ERK-integrin αVβ3-FAK cascade

(2011) Shinji Matsuda et al.   JOURNAL OF CELLULAR PHYSIOLOGY

BDNF Promotes EGF-Induced Proliferation and Migration of Human Fetal Neural Stem/Progenitor Cells via the PI3K/Akt Pathway

(2011) Qi Zhang et al.   MOLECULES

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL