标题
The Role of the Nrf2 Signaling in Obesity and Insulin Resistance
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 18, Pages 6973
出版商
MDPI AG
发表日期
2020-09-22
DOI
10.3390/ijms21186973
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Adipose Tissue Macrophage Phenotypes and Characteristics: The Key to Insulin Resistance in Obesity and Metabolic Disorders
- (2020) Yinhua Ni et al. Obesity
- Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance
- (2020) Valerio Azzimato et al. Science Translational Medicine
- The endocrine function of adipose tissues in health and cardiometabolic disease
- (2019) Ludger Scheja et al. Nature Reviews Endocrinology
- Parthenolide, a feverfew-derived phytochemical, ameliorates obesity and obesity-induced inflammatory responses via the Nrf2/Keap1 pathway
- (2019) Chae Young Kim et al. PHARMACOLOGICAL RESEARCH
- Insulin Signaling and Insulin Resistance Facilitate Trained Immunity in Macrophages Through Metabolic and Epigenetic Changes
- (2019) Eleftheria Ieronymaki et al. Frontiers in Immunology
- Chronic inflammation in the etiology of disease across the life span
- (2019) David Furman et al. NATURE MEDICINE
- Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice
- (2018) Dionysios V Chartoumpekis et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Insulin resistance in obesity: an overview of fundamental alterations
- (2018) Rocco Barazzoni et al. Eating and Weight Disorders-Studies on Anorexia Bulimia and Obesity
- Obesity as a Disease
- (2018) Jagriti Upadhyay et al. MEDICAL CLINICS OF NORTH AMERICA
- ROS signalling in the biology of cancer
- (2018) Jennifer N. Moloney et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Notoginsenoside R1 ameliorates diabetic encephalopathy by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation
- (2018) Yadong Zhai et al. Oncotarget
- Modulating NRF2 in Disease: Timing Is Everything
- (2018) Matthew Dodson et al. Annual Review of Pharmacology and Toxicology
- The epidemiology of obesity
- (2018) Yu Chung Chooi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Insulin resistance: Review of the underlying molecular mechanisms
- (2018) Habib Yaribeygi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Arbutin attenuates LPS-induced lung injury via Sirt1/ Nrf2/ NF-κBp65 pathway
- (2018) Jinyan Ye et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Global Obesity Epidemic Worsening
- (2017) M.J. Friedrich JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Arachidonic Acid Induces ARE/Nrf2-Dependent Heme Oxygenase-1 Transcription in Rat Brain Astrocytes
- (2017) Chih-Chung Lin et al. MOLECULAR NEUROBIOLOGY
- Adapting to obesity with adipose tissue inflammation
- (2017) Shannon M. Reilly et al. Nature Reviews Endocrinology
- Oxidative Stress: Harms and Benefits for Human Health
- (2017) Gabriele Pizzino et al. Oxidative Medicine and Cellular Longevity
- Macrophage function in obesity-induced inflammation and insulin resistance
- (2017) Mario A. R. Lauterbach et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress
- (2017) Yoko Yagishita et al. Cell Reports
- The etiology of oxidative stress in insulin resistance
- (2017) Samantha Hurrle et al. Biomedical Journal
- Activation of Nrf2 signaling by natural products-can it alleviate diabetes?
- (2017) Manuel Matzinger et al. BIOTECHNOLOGY ADVANCES
- Transcriptional Regulation by Nrf2
- (2017) Claudia Tonelli et al. ANTIOXIDANTS & REDOX SIGNALING
- Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet
- (2016) Stephen L. Slocum et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux
- (2016) Varman T. Samuel et al. JOURNAL OF CLINICAL INVESTIGATION
- Adipose tissue regulates insulin sensitivity: role of adipogenesis,de novolipogenesis and novel lipids
- (2016) U. Smith et al. JOURNAL OF INTERNAL MEDICINE
- Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism
- (2016) Akira Uruno et al. MOLECULAR AND CELLULAR BIOLOGY
- Deletion of Nrf2 leads to hepatic insulin resistance via the activation of NF-κB in mice fed a high-fat diet
- (2016) Zhenxiong Liu et al. Molecular Medicine Reports
- Harmful and Beneficial Role of ROS
- (2016) Sergio Di Meo et al. Oxidative Medicine and Cellular Longevity
- Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
- (2016) Eri H. Kobayashi et al. Nature Communications
- Nrf2 regulates ROS production by mitochondria and NADPH oxidase
- (2015) Stjepana Kovac et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance
- (2015) Jonas Benzler et al. DIABETES
- Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies
- (2015) Prasenjit Manna et al. Metabolic Syndrome and Related Disorders
- Macrophage recruitment in obese adipose tissue
- (2015) Y. Bai et al. Obesity Reviews
- Mechanisms Linking Inflammation to Insulin Resistance
- (2015) Li Chen et al. International Journal of Endocrinology
- Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages
- (2014) Mario Kratz et al. Cell Metabolism
- Oxidative Stress in Obesity: A Critical Component in Human Diseases
- (2014) Lucia Marseglia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Obesity indices and inflammatory markers in obese non-diabetic normo- and hypertensive patients: a comparative pilot study
- (2014) Mariusz Stępień et al. Lipids in Health and Disease
- Susceptibility of Nrf2-Null Mice to Steatohepatitis and Cirrhosis upon Consumption of a High-Fat Diet Is Associated with Oxidative Stress, Perturbation of the Unfolded Protein Response, and Disturbance in the Expression of Metabolic Enzymes but Not with Insulin Resistance
- (2014) P. J. Meakin et al. MOLECULAR AND CELLULAR BIOLOGY
- Insulin Receptor Signaling in Normal and Insulin-Resistant States
- (2014) J. Boucher et al. Cold Spring Harbor Perspectives in Biology
- Macrophage Cytokines: Involvement in Immunity and Infectious Diseases
- (2014) Guillermo Arango Duque et al. Frontiers in Immunology
- Inflammation, Cytokines and Insulin Resistance: A Clinical Perspective
- (2013) Verena Wieser et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Obesity-Associated Oxidative Stress: Strategies Finalized to Improve Redox State
- (2013) Isabella Savini et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response
- (2013) Tao Jiang et al. KIDNEY INTERNATIONAL
- Hypoxia and Adipose Tissue Function and Dysfunction in Obesity
- (2013) Paul Trayhurn PHYSIOLOGICAL REVIEWS
- Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
- (2013) Heriberto Rodríguez-Hernández et al. International Journal of Endocrinology
- Mechanisms of insulin resistance in obesity
- (2013) Jianping Ye Frontiers of Medicine
- Mitochondrial Fatty Acid Oxidation in Obesity
- (2012) Dolors Serra et al. ANTIOXIDANTS & REDOX SIGNALING
- Enhanced Nrf2 Activity Worsens Insulin Resistance, Impairs Lipid Accumulation in Adipose Tissue, and Increases Hepatic Steatosis in Leptin-Deficient Mice
- (2012) J. Xu et al. DIABETES
- Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome
- (2012) P. Xue et al. DIABETES
- Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance
- (2012) Akshaya K. Meher et al. FREE RADICAL BIOLOGY AND MEDICINE
- Resveratrol Upregulates Nrf2 Expression To Attenuate Methylglyoxal-Induced Insulin Resistance in Hep G2 Cells
- (2012) An-Sheng Cheng et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Inhibition of NF-κB nuclear translocation via HO-1 activation underlies α-tocopheryl succinate toxicity
- (2012) Ilaria Bellezza et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Differentiation of Human Adipose-Derived Stem Cells into Fat Involves Reactive Oxygen Species and Forkhead Box O1 Mediated Upregulation of Antioxidant Enzymes
- (2012) Masayoshi Higuchi et al. STEM CELLS AND DEVELOPMENT
- Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet
- (2012) Yu-Kun Jennifer Zhang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway
- (2011) Miao Yu et al. CELLULAR SIGNALLING
- Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states
- (2011) David L Morris et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Nrf2 Represses FGF21 During Long-Term High-Fat Diet-Induced Obesity in Mice
- (2011) D. V. Chartoumpekis et al. DIABETES
- Insulin effects in muscle and adipose tissue
- (2011) George Dimitriadis et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Inflammation, Oxidative Stress, and Obesity
- (2011) Alba Fernández-Sánchez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Forming functional fat: a growing understanding of adipocyte differentiation
- (2011) Ana G. Cristancho et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Oltipraz upregulates the nuclear respiratory factor 2 alpha subunit (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice
- (2010) Z. Yu et al. DIABETOLOGIA
- Oxidative stress, inflammation, and cancer: How are they linked?
- (2010) Simone Reuter et al. FREE RADICAL BIOLOGY AND MEDICINE
- Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity
- (2010) Jingbo Pi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide
- (2009) Soona Shin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Reactive Oxygen Species Facilitate Adipocyte Differentiation by Accelerating Mitotic Clonal Expansion
- (2009) Haemi Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammation resolution: Does the bone marrow have a say?
- (2008) Mario Romano AMERICAN JOURNAL OF HEMATOLOGY
- NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK
- (2008) Guang-Hui Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity
- (2008) T. Yamamoto et al. MOLECULAR AND CELLULAR BIOLOGY
- Fuel utilization by hypothalamic neurons: roles for ROS
- (2008) Tamas L. Horvath et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More