Neural Control of Immunity in Hypertension: Council on Hypertension Mid Career Award for Research Excellence, 2019

B6.Rag1 Knockout Mice Generated at the Jackson Laboratory in 2009 Show a Robust Wild-Type Hypertensive Phenotype in Response to Ang II (Angiotensin II)

(2020) Anika Seniuk et al.   HYPERTENSION

Neuroimmune crosstalk in the pathophysiology of hypertension

(2019) Laura Calvillo et al.   Nature Reviews Cardiology

Apical splenic nerve electrical stimulation discloses an anti-inflammatory pathway relying on adrenergic and nicotinic receptors in myeloid cells

(2019) Mélanie Guyot et al.   BRAIN BEHAVIOR AND IMMUNITY

Deoxycorticosterone acetate-salt hypertension activates placental growth factor in the spleen to couple sympathetic drive and immune system activation

(2018) Marialuisa Perrotta et al.   CARDIOVASCULAR RESEARCH

Hypertension: Focus on autoimmunity and oxidative stress

(2018) Heather Y. Small et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vascular toxicities with VEGF inhibitor therapies–focus on hypertension and arterial thrombotic events

(2018) Rhian M. Touyz et al.   Journal of the American Society of Hypertension

Low-Dose Methotrexate for the Prevention of Atherosclerotic Events

(2018) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

(2017) Paul K. Whelton et al.   HYPERTENSION

Mechanisms and Therapeutic Relevance of Neuro-immune Communication

(2017) Sangeeta S. Chavan et al.   IMMUNITY

The immunology of hypertension

(2017) Allison E. Norlander et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive StimuliNovelty and Significance

(2016) Hana A. Itani et al.   CIRCULATION RESEARCH

Resting Afferent Renal Nerve Discharge and Renal InflammationNovelty and Significance

(2016) Christopher T. Banek et al.   HYPERTENSION

Deficiency of T-regulatory cells exaggerates angiotensin II-induced microvascular injury by enhancing immune responses

(2016) Muhammad Oneeb Rehman Mian et al.   JOURNAL OF HYPERTENSION

A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication

(2016) Daniela Carnevale et al.   Nature Communications

Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II–Induced HypertensionNovelty and Significance

(2015) Liang Xiao et al.   CIRCULATION RESEARCH

The Sympathetic Nervous System in Hypertension: Back to the Future?

(2015) Murray Esler   CURRENT HYPERTENSION REPORTS

Refractory HypertensionNovelty and Significance

(2015) Tanja Dudenbostel et al.   HYPERTENSION

Obligatory Role for B Cells in the Development of Angiotensin II–Dependent HypertensionNovelty and Significance

(2015) Christopher T. Chan et al.   HYPERTENSION

Association Between Anti-TNF Therapy for Rheumatoid Arthritis and Hypertension

(2015) Qingwei Zhao et al.   MEDICINE

Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity

(2015) Gerald J Prud'homme et al.   Oncotarget

The Autonomic Nervous System and Hypertension

(2014) Giuseppe Mancia et al.   CIRCULATION RESEARCH

High prevalence of masked uncontrolled hypertension in people with treated hypertension

(2014) J. R. Banegas et al.   EUROPEAN HEART JOURNAL

Oligoclonal CD8 + T Cells Play a Critical Role in the Development of Hypertension

(2014) Daniel W. Trott et al.   HYPERTENSION

The Angiogenic Factor PlGF Mediates a Neuroimmune Interaction in the Spleen to Allow the Onset of Hypertension

(2014) Daniela Carnevale et al.   IMMUNITY

DC isoketal-modified proteins activate T cells and promote hypertension

(2014) Annet Kirabo et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage

(2013) David L. Mattson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma

(2013) Matija Snuderl et al.   CELL

A New Approach to Residual Risk in Treated Hypertension—3P Screening

(2013) Allan D. Struthers   HYPERTENSION

The Mosaic Theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension

(2013) David G. Harrison   Journal of the American Society of Hypertension

Stress-dependent hypertension and the role of T lymphocytes

(2012) Paul J. Marvar et al.   EXPERIMENTAL PHYSIOLOGY

Sympathetic Signatures of Cardiovascular Disease

(2012) John W. Osborn et al.   HYPERTENSION

Lysozyme M–Positive Monocytes Mediate Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

(2011) Philip Wenzel et al.   CIRCULATION

T Regulatory Lymphocytes Prevent Angiotensin II–Induced Hypertension and Vascular Injury

(2011) Tlili Barhoumi et al.   HYPERTENSION

Under pressure: the search for the essential mechanisms of hypertension

(2011) Thomas M Coffman   NATURE MEDICINE

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

(2011) M. Rosas-Ballina et al.   SCIENCE

Sympathetic Neural Activity in Hypertension and Related Diseases

(2010) G. Grassi   AMERICAN JOURNAL OF HYPERTENSION

In search of autonomic balance: the good, the bad, and the ugly

(2010) François M. Abboud   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Lymphocyte responses exacerbate angiotensin II-dependent hypertension

(2010) Steven D. Crowley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth

(2010) Carlos Bais et al.   CELL

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

(2010) Sara Van de Veire et al.   CELL

Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension

(2010) Antony Vinh et al.   CIRCULATION

Central and Peripheral Mechanisms of T-Lymphocyte Activation and Vascular Inflammation Produced by Angiotensin II–Induced Hypertension

(2010) Paul J. Marvar et al.   CIRCULATION RESEARCH

Sympathetic Nervous System Overactivity and Its Role in the Development of Cardiovascular Disease

(2010) Simon C. Malpas   PHYSIOLOGICAL REVIEWS

Region-specific changes in sympathetic nerve activity in angiotensin II-salt hypertension in the rat

(2009) John W. Osborn et al.   EXPERIMENTAL PHYSIOLOGY

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

Residual cardiovascular risk in treated hypertension and hyperlipidaemia: the PRIME Study

(2009) J Blacher et al.   JOURNAL OF HUMAN HYPERTENSION

The Neurology of the Immune System: Neural Reflexes Regulate Immunity

(2009) Mauricio Rosas-Ballina et al.   NEURON

The Hypertension Paradox — More Uncontrolled Disease despite Improved Therapy

(2009) Aram V. Chobanian   NEW ENGLAND JOURNAL OF MEDICINE

Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia

(2008) M. Rosas-Ballina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA