A long non‐coding RNA ( Lrap ) modulates brain gene expression and levels of alcohol consumption in rats

Identification of a Functional Non-coding Variant in the GABAA Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research

(2019) Megan K. Mulligan et al.   Frontiers in Genetics

Aberrant oligodendroglial–vascular interactions disrupt the blood–brain barrier, triggering CNS inflammation

(2019) Jianqin Niu et al.   NATURE NEUROSCIENCE

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

Long Non-Coding RNA Expression Levels Modulate Cell-Type-Specific Splicing Patterns by Altering Their Interaction Landscape with RNA-Binding Proteins

(2019) Felipe Wendt Porto et al.   Genes

Reduced expression of purinergic P2X4 receptors increases voluntary ethanol intake in C57BL/6J mice

(2018) Sheraz Khoja et al.   ALCOHOL

Cannabinoid-1 receptor neutral antagonist reduces binge-like alcohol consumption and alcohol-induced accumbal dopaminergic signaling

(2018) Andrea Balla et al.   NEUROPHARMACOLOGY

Splicing regulation by long noncoding RNAs

(2018) Natali Romero-Barrios et al.   NUCLEIC ACIDS RESEARCH

Nuclear Long Noncoding RNAs: Key Regulators of Gene Expression

(2018) Qinyu Sun et al.   TRENDS IN GENETICS

Notch1 deficiency in postnatal neural progenitor cells in the dentate gyrus leads to emotional and cognitive impairment

(2017) Shufang Feng et al.   FASEB JOURNAL

Genetics of alcohol consumption in Drosophila melanogaster

(2017) S. Fochler et al.   GENES BRAIN AND BEHAVIOR

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones

(2017) Anna Malinová et al.   JOURNAL OF CELL BIOLOGY

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

(2017) T-K Clarke et al.   MOLECULAR PSYCHIATRY

Poly(ADP-ribose) polymerase-1 regulates microglia mediated decrease of endothelial tight junction integrity

(2017) Abbas Rezaeian Mehrabadi et al.   NEUROCHEMISTRY INTERNATIONAL

Mutation of the inhibitory ethanol site in GABA A ρ1 receptors promotes tolerance to ethanol-induced motor incoordination

(2017) Yuri A. Blednov et al.   NEUROPHARMACOLOGY

Mechanisms of Long Non-Coding RNAs in the Assembly and Plasticity of Neural Circuitry

(2017) Andi Wang et al.   Frontiers in Neural Circuits

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

(2017) Philippe Cloutier et al.   Nature Communications

P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology

(2017) Leanne Stokes et al.   Frontiers in Pharmacology

How do lncRNAs regulate transcription?

(2017) Yicheng Long et al.   Science Advances

The Arp2/3 Complex Is Essential for Distinct Stages of Spine Synapse Maturation, Including Synapse Unsilencing

(2016) E. F. Spence et al.   JOURNAL OF NEUROSCIENCE

Uncovering the liver’s role in immunity through RNA co-expression networks

(2016) Kylie K. Harrall et al.   MAMMALIAN GENOME

Genome-wide changes in lncRNA, splicing and regional gene expression patterns in autism

(2016) Neelroop N. Parikshak et al.   NATURE

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

The Neuroimmune Basis of Excessive Alcohol Consumption

(2016) Jody Mayfield et al.   NEUROPSYCHOPHARMACOLOGY

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The neuroimmune transcriptome and alcohol dependence: potential for targeted therapies

(2016) Anna Warden et al.   PHARMACOGENOMICS

Involvement of Purinergic P2X4 Receptors in Alcohol Intake of High-Alcohol-Drinking (HAD) Rats

(2015) Kelle M. Franklin et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Genomic landscape of rat strain and substrain variation

(2015) Roel Hermsen et al.   BMC GENOMICS

The sequenced rat brain transcriptome - its use in identifying networks predisposing alcohol consumption

(2015) Laura M. Saba et al.   FEBS Journal

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature

(2015) Inma Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alcohol sensory processing and its relevance for ingestion

(2015) Susan M. Brasser et al.   PHYSIOLOGY & BEHAVIOR

The human transcriptome across tissues and individuals

(2015) M. Mele et al.   SCIENCE

A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature

(2015) Inma Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Comprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination

(2015) Xiaomin Dong et al.   PLoS Genetics

Biochemical, Biomedical and Metabolic Aspects of Imidazole-Containing Dipeptides with the Inherent Complexity to Neurodegenerative Diseases and Various States of Mental Well-Being: A Challenging Correction and Neurotherapeutic Pharmaceutical Biotechnology for Treating Cognitive Deficits, Depression and Intellectual Disabilities

(2014) Mark Babizhayev   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Contribution of P2X4 Receptors to Ethanol Intake in Male C57BL/6 Mice

(2014) Letisha R. Wyatt et al.   NEUROCHEMICAL RESEARCH

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional regulatory functions of nuclear long noncoding RNAs

(2014) Keith W. Vance et al.   TRENDS IN GENETICS

Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System

(2014) Andrew R. Bassett et al.   Cell Reports

P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders

(2014) Kelle M. Franklin et al.   Frontiers in Neuroscience

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

Loss of metabotropic glutamate receptor 2 escalates alcohol consumption

(2013) Z. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Identification and function of long non-coding RNA

(2013) Carl Ernst et al.   Frontiers in Cellular Neuroscience

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Role of Feeding-Related Pathways in Alcohol Dependence: A Focus on Sweet Preference, NPY, and Ghrelin

(2010) Lorenzo Leggio et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Slc35c2 Promotes Notch1 Fucosylation and Is Required for Optimal Notch Signaling in Mammalian Cells

(2010) Linchao Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetical genomic determinants of alcohol consumption in rats and humans

(2009) Boris Tabakoff et al.   BMC BIOLOGY

Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

(2009) J. T. Lee   GENES & DEVELOPMENT

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS