Deficiency in the function of inhibitory interneurons contributes to glutamate-associated central sensitization through GABABR2-SynCAM1 signaling in chronic migraine rats

EphrinB/EphB Signaling Contributes to the Synaptic Plasticity of Chronic Migraine Through NR2B Phosphorylation

(2020) Jiang Wang et al.   NEUROSCIENCE

Endogenous opioid peptides in the descending pain modulatory circuit

(2020) Elena E. Bagley et al.   NEUROPHARMACOLOGY

Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model

(2019) Wei He et al.   Journal of Neuroinflammation

Fremanezumab versus placebo for migraine prevention in patients with documented failure to up to four migraine preventive medication classes (FOCUS): a randomised, double-blind, placebo-controlled, phase 3b trial

(2019) Michel D Ferrari et al.   LANCET

GABA releases from parvalbumin-expressing and unspecific GABAergic neurons onto CA1 pyramidal cells are differentially modulated by presynaptic GABAB receptors in mouse hippocampus

(2019) Yingqian Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Migraine

(2018) David W Dodick   LANCET

Structural biology of GABA B receptor

(2018) Aurel Frangaj et al.   NEUROPHARMACOLOGY

Postsynaptic GABA B Rs Inhibit L-Type Calcium Channels and Abolish Long-Term Potentiation in Hippocampal Somatostatin Interneurons

(2018) Sam A. Booker et al.   Cell Reports

Microglia P2X4 receptor contributes to central sensitization following recurrent nitroglycerin stimulation

(2018) Ting Long et al.   Journal of Neuroinflammation

Presynaptic mGlu1 Receptors Control GABAB Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings

(2018) Matteo Vergassola et al.   Frontiers in Molecular Neuroscience

NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model

(2018) Xue-Ying Wang et al.   JOURNAL OF HEADACHE AND PAIN

Dexmedetomidine protects rats from postoperative cognitive dysfunction via regulating the GABAB R-mediated cAMP-PKA-CREB signaling pathway

(2018) Yun-Sheng Zhu et al.   NEUROPATHOLOGY

Inhibition of Nerve Growth Factor Signaling Alleviates Repeated Dural Stimulation-induced Hyperalgesia in Rats

(2018) Huiru Zhou et al.   NEUROSCIENCE

The Trigeminovascular Pathway: Role of CGRP and CGRP Receptors in Migraine

(2017) Lars Edvinsson   HEADACHE

The role of calcitonin gene–related peptide in peripheral and central pain mechanisms including migraine

(2017) Smriti Iyengar et al.   PAIN

Disrupted functional connectivity between the periaqueductal gray and other brain regions in a rat model of recurrent headache

(2017) Zhihua Jia et al.   Scientific Reports

Antinociception of spirocyclopiperazinium salt compound LXM-10-M targeting α7 nicotinic receptor and M4 muscarinic receptor and inhibiting CaMKIIα/CREB/CGRP signaling pathway in mice

(2016) Dan Wan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Insular balance of glutamatergic and GABAergic signaling modulates pain processing

(2016) Christopher J. Watson   PAIN

Inhibition of the cAMP/PKA/CREB Pathway Contributes to the Analgesic Effects of Electroacupuncture in the Anterior Cingulate Cortex in a Rat Pain Memory Model

(2016) Xiao-Mei Shao et al.   NEURAL PLASTICITY

Migraine and neuropeptides

(2015) János Tajti et al.   NEUROPEPTIDES

GABAA receptor α2 subtype activation suppresses retinal spreading depression

(2015) M. Wang et al.   NEUROSCIENCE

Migraine and perimenopause

(2014) Khatera Ibrahimi et al.   MATURITAS

Involvement of spinal PKA/CREB signaling pathway in the development of bone cancer pain

(2014) Li-Hua Hang et al.   Pharmacological Reports

Pearls and pitfalls in experimental in vivo models of headache: Conscious behavioral research

(2013) Marcela Romero-Reyes et al.   CEPHALALGIA

The International Classification of Headache Disorders, 3rd edition (beta version)

(2013)   CEPHALALGIA

A chronic animal model of migraine, induced by repeated meningeal nociception, characterized by a behavioral and pharmacological approach

(2013) Agustin Melo-Carrillo et al.   CEPHALALGIA

GAD67 Deficiency in Parvalbumin Interneurons Produces Deficits in Inhibitory Transmission and Network Disinhibition in Mouse Prefrontal Cortex

(2013) M. S. Lazarus et al.   CEREBRAL CORTEX

Differential GABAB-Receptor-Mediated Effects in Perisomatic- and Dendrite-Targeting Parvalbumin Interneurons

(2013) S. A. Booker et al.   JOURNAL OF NEUROSCIENCE

Noise-induced hearing loss is correlated with alterations in the expression of GABAB receptors and PKC gamma in the murine cochlear nucleus complex

(2013) Zhen-Zhen Kou et al.   Frontiers in Neuroanatomy

Impairment of GABAB receptor dimer by endogenous 14-3-3ζ in chronic pain conditions

(2012) Sophie Laffray et al.   EMBO JOURNAL

Regulation of neuronal GABAB receptor functions by subunit composition

(2012) Martin Gassmann et al.   NATURE REVIEWS NEUROSCIENCE

Chronic compression or acute dissociation of dorsal root ganglion induces cAMP-dependent neuronal hyperexcitability through activation of PAR2

(2012) Zhi-Jiang Huang et al.   PAIN

Pathophysiology of Chronic Migraine and Mode of Action of Preventive Medications

(2011) Ninan T. Mathew   HEADACHE

Triptans attenuate capsaicin-induced CREB phosphorylation within the trigeminal nucleus caudalis: a mechanism to prevent central sensitization?

(2011) Dimos D. Mitsikostas et al.   JOURNAL OF HEADACHE AND PAIN

Loss of GABAergic Interneurons in Laminae I–III of the Spinal Cord Dorsal Horn Contributes to Reduced GABAergic Tone and Neuropathic Pain after Spinal Cord Injury

(2010) Jason G. Meisner et al.   JOURNAL OF NEUROTRAUMA

Central mechanisms of pathological pain

(2010) Rohini Kuner   NATURE MEDICINE

SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning

(2010) Elissa M. Robbins et al.   NEURON

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

(2010) Wendy M. Knowlton et al.   PAIN

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

(2009) Alban Latremoliere et al.   JOURNAL OF PAIN

SynCAM1 recruits NMDA receptors via Protein 4.1B

(2009) Jennifer L. Hoy et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Peripheral involvement of PKA and PKC in subcutaneous bee venom-induced persistent nociception, mechanical hyperalgesia, and inflammation in rats

(2007) Hui-Sheng Chen et al.   PAIN