Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation

标题
Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation
作者
关键词
Azide-alkyne click reaction, Cereblon, p38 MAPK, PROTAC linker optimization, Protein degradation, Thalidomide derivative
出版物
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 201, Issue -, Pages 112451
出版商
Elsevier BV
发表日期
2020-06-18
DOI
10.1016/j.ejmech.2020.112451

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