Article
Biochemistry & Molecular Biology
Lijuan Shi, Yeling Li, Shaojie Zhang, Xiaotang Gong, Jing Xu, Yuanqiang Guo
Summary: In this study, a new inulin-type fructan CIP70-1 was extracted from chicory and showed weak antitumor activity. To enhance its antitumor effects, inulin-based selenium nanoparticles (CIP-SeNPs) were developed and found to have stronger inhibitory effects on cancer cells compared to CIP70-1 alone. The in vivo antitumor effects of CIP-SeNPs were also confirmed using zebrafish models.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Cell Biology
Xuejiao Yuan, Yanfeng Zhou, Jinli Sun, Shanshan Wang, Xingjie Hu, Jiyu Li, Jing Huang, Nan Chen
Summary: Acute liver injury (ALI) is a severe liver disease characterized by sudden hepatocyte necrosis and liver function deterioration. This study develops hepatocyte-targeting self-assembling nanoparticles encapsulating an organic Selenium compound, which effectively removes reactive oxygen species (ROS) and protects hepatocyte viability. The nanoparticles, functionalized with a liver-targeting ligand, exhibit enhanced hepatocyte uptake and successfully reduce liver damage in mouse models of ALI induced by acetaminophen or carbon tetrachloride.
CELL PROLIFERATION
(2023)
Article
Chemistry, Multidisciplinary
David Mabwa, Teo Kubiena, Harriet Parnell, Rong Su, David Furniss, Zhuoqi Tang, Richard Leach, Trevor M. Benson, Colin A. Scotchford, Angela B. Seddon
Summary: The cytotoxicity of Ge-Sb-Se chalcogenide optical glass fibres on 3T3 mouse fibroblast cells was investigated. The study found that fibres treated with oxidation may cause cytotoxicity, attributed to the notable pH change from neutral to acidic environment upon dissolution of the oxide layer.
Article
Chemistry, Analytical
Jianxiong Zhou, Ruiying Wu, Xiao Fu, Jinmei Wu, Qingsong Mei
Summary: The novel ratio-adjustable fluorescent nanoprobe exhibits an extremely low detection limit and a broader linear detection range compared to traditional methods, showing great potential for diverse disease diagnosis applications.
ANALYTICAL CHEMISTRY
(2021)
Review
Agriculture, Dairy & Animal Science
Iqra Bano, Sylvie Skalickova, Safia Arbab, Lenka Urbankova, Pavel Horky
Summary: Animal nutrition is crucial for the productivity and sustainability of livestock production systems. Selenium nanoparticles (SeNPs) have both beneficial uses and potential toxicity in animals, and ensuring safety through a safe-by-strategy approach is important.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2022)
Article
Polymer Science
Tarek Abou Elmaaty, Khaled Sayed-Ahmed, Radwan Mohamed Ali, Kholoud El-Khodary, Shereen A. Abdeldayem
Summary: This article focuses on the development of leather materials with antibacterial properties and coloring ability using selenium nanoparticles. The results show that the treated leather material exhibits enhanced antibacterial activity and coloration, as well as excellent color fastness properties.
Review
Plant Sciences
Zsuzsanna Kolbert, Reka Szollosi, Gabor Feigl, Zoltan Konya, Andrea Ronavari
Summary: Plant nanobiology research provides a scientific basis for the agricultural use of nanoparticles, showing that nanomaterials can stimulate endogenous NO synthesis and signaling in plants and also have stress-alleviating effects. Evaluating the effects of NO-releasing NPs on plants has recently begun, and the development of an NP-based nanosensor for NO detection in plants offers new perspectives for basic research and plant health evaluation in agriculture.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Food Science & Technology
Lei Qiao, Xina Dou, Xiaofan Song, Jiajing Chang, Shanyao Pi, Xinyi Zhang, Lixu Zhu, Xiaonan Zeng, Chunlan Xu
Summary: This study investigated the association between gut microbiota and metabolites under oxidative stress conditions after supplementation of Selenium nanoparticles (SeNPs). The results showed that SeNPs supplementation attenuated diquat-induced acute toxicity in mice by reducing inflammation and biochemical markers in serum. SeNPs also reversed the perturbed gut microbiota composition induced by diquat and increased the abundance of beneficial bacteria. Additionally, SeNPs supplementation regulated the production of various metabolites. Microbiomemetabolome correlation analysis suggested that Parabacteroides was the key bacteria for SeNPs intervention. Overall, this study demonstrated that dietary SeNPs supplementation can extensively modulate the gut microbiota and its metabolism, thereby alleviating diquat-induced acute toxicity.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Food Science & Technology
Akaber T. Keshta, Ahmed M. Fathallah, Yasser A. Attia, Emad A. Salem, Shimaa H. Watad
Summary: This study aimed to investigate the ameliorative effect of selenium nanoparticles (SeNPs) against cisplatin-induced testicular toxicity in male rats. The results showed that cisplatin treatment caused a decrease in body weight, testis weight, antioxidant activities, testosterone concentration, and steroidogenetic expression, as well as an increase in oxidative stress and sperm abnormality. However, co-administration of SeNPs alleviated the harmful effects of cisplatin by reducing oxidative stress. Therefore, SeNPs may have a potential protective effect against cisplatin-induced testicular toxicity.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Environmental Sciences
Rasha M. Hassan, Mai Elsayed, Tahany E. Kholief, Naglaa H. M. Hassanen, Jehan A. Gafer, Yasser A. Attia
Summary: In the fructose/streptozotocin diabetic rat model, oral administration of ZnONPs, Cr(2)O(3)NPs, SeNPs, and their combination can improve biochemical and genetic parameters towards normal levels and ameliorate the consequences of diabetes, as confirmed by histological and biochemical results.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Agronomy
Abolghassem Emamverdian, Abazar Ghorbani, Yang Li, Necla Pehlivan, James Barker, Yulong Ding, Guohua Liu, Meisam Zargar
Summary: Bamboo is nutritionally valuable globally due to its high calorie and nutritional fiber content and low cholesterol. However, it has been found that bamboo shoots also contain significant amounts of heavy metals, including arsenic. In this study, researchers investigated the possible attenuation of arsenic toxicity in bamboo plants through the co-application of iron oxide nanoparticles and selenium nanoparticles. The results showed that the co-application significantly improved antioxidant enzyme activities, total flavonoid and phenolic content, and various physiological and growth parameters of the bamboo plants. The most effective approach for increasing bamboo's ability to recover from arsenic toxicity was the concurrent use of selenium nanoparticles and iron oxide nanoparticles.
Article
Agriculture, Dairy & Animal Science
A. Lepczynski, A. Herosimczyk, M. Barszcz, M. Ozgo, K. Michalek, M. Grabowska, A. Tusnio, D. Szczerbinska, J. Skomial
Summary: The dietary supplementation of dried chicory root or native chicory inulin improved liver histology and oxidative balance in growing pigs, while affecting mineral and heavy metal content. Both supplements had the potential to enhance Se status and oxidoreductive homeostasis in the animals.
Review
Biochemistry & Molecular Biology
Arbindra Timilsina, Wenxu Dong, Mirza Hasanuzzaman, Binbin Liu, Chunsheng Hu
Summary: Plant survival and adaptation during oxygen deprivation, caused by various biotic and abiotic factors, rely on mechanisms such as fermentation, antioxidant enzymes, and the reduction pathways of nitrate and nitric oxide. Understanding the molecular mechanisms involved in reducing nitric oxide toxicity is important not only for plant physiology, but also for addressing uncertainties in the global nitrous oxide budget.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Plant Sciences
Anjali Pande, Bong-Gyu Mun, Nusrat Jahan Methela, Waqas Rahim, Da-Sol Lee, Geun-Mo Lee, Jeum Kyu Hong, Adil Hussain, Gary Loake, Byung-Wook Yun
Summary: Environmental pollutants like heavy metals pose a serious threat to crops and human health. Plants combat heavy metal toxicity by regulating their redox machinery, with nitric oxide playing a major role. Recent studies have shown that nitric oxide-releasing nanoparticles can be effective in mitigating heavy metal stress in plants.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Shevanuja Theivendran, Zhengying Gu, Jie Tang, Yannan Yang, Hao Song, Yang Yang, Min Zhang, Dan Cheng, Chengzhong Yu
Summary: This study reports the synthesis of a nanoparticle-based NO delivery platform that utilizes tetrasulfide-modified organosilica nanoparticles for effective NO delivery and macrophage activation. The enhanced intracellular delivery of NO resulted in macrophage activation and delayed tumor growth in a breast cancer model.
Article
Ophthalmology
Mahtab Haghighat, Alireza Iranbakhsh, Javad Baharara, Mostafa Ebadi, Fattah Sotoodehnejadnematalahi
Summary: Stem cell therapy is considered a promising approach for restoring degenerative cells due to retinal degenerative diseases, and the addition of beta-carotene to the differentiation medium along with using appropriate scaffolds can induce higher differentiation levels of mouse ciliary epithelium-derived MSCs into specialized retinal cells.
EXPERIMENTAL EYE RESEARCH
(2021)
Article
Food Science & Technology
Fatemeh Adami Ghamsari, Maryam Tajabadi Ebrahimi, Maryam Bagheri Varzaneh, Alireza Iranbakhsh, Abbas Akhavan Sepahi
Summary: This study investigates the detoxification ability of mycotoxin-organic binders, including Lactobacillus and yeast cell wall, on reducing DON contamination. The combination of Lactobacillus brevis TD4 and Lactobacillus paracasei TD3 in PBS solution and L. brevis TD4 and L. brevis TD10 in MRS broth medium showed the highest reduction rate of DON.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Article
Plant Sciences
Ameneh Vafaie Moghadam, Alireza Iranbakhsh, Sara Saadatmand, Mostafa Ebadi, Zahra Oraghi Ardebili
Summary: This study investigated the physiological, epigenetic, and transcriptional responses of Datura stramonium to long-term exposure to different concentrations of zinc oxide nanoparticles. It found that lower concentrations promoted growth and nutrient absorption, while higher concentrations caused phytotoxicity and changes in gene expression related to metal accumulation. These findings deepen our understanding of the molecular mechanisms involved in plant responses to nanomaterial exposure.
JOURNAL OF PLANT GROWTH REGULATION
(2022)
Article
Plant Sciences
Tahereh Mirakhorli, Zahra Oraghi Ardebili, Alireza Ladan-Moghadam, Elham Danaee
Summary: The study demonstrated that the application of nitric oxide (NO) had positive effects on the growth and physiological responses of soybean, including increasing biomass, leaf numbers, and pod numbers. It also enhanced nutrient content in leaves and seeds, while affecting plant growth and metabolism through upregulating the expression of multiple genes.
JOURNAL OF PLANT GROWTH REGULATION
(2022)
Article
Environmental Sciences
Nasim Ghasemzadeh, Alireza Iranbakhsh, Zahra Oraghi-Ardebili, Sara Saadatmand, Sodabeh Jahanbakhsh-Godehkahriz
Summary: Cold plasma application can mitigate the damage of heavy metals on plants, improve yield and stress resistance of wheat, and affect the fatty acid profile. The use of 120 seconds of cold plasma treatment can effectively alleviate cadmium stress.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Ghasem Asgari-Targhi, Alireza Iranbakhsh, Zahra Oraghi Ardebili, Adel Hatami Tooski
Summary: The study successfully synthesized chitosan/zinc oxide nanocomposite and demonstrated its capability to enhance plant growth and biomass in vitro conditions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Engineering, Environmental
Shokufeh Beglari, Fariba Khodagholi, Hamid Gholami Pourbadie, Alireza Iranbakhsh, Mahdi Rohani
Summary: Probiotic lactic acid bacteria have shown potential in reducing nickel toxicity through biosorption and bioaccumulation methods. Four strains of nickel-resistant bacteria were found to be effective in reducing nickel from culture medium, highlighting their potential use in gut remediation and edible industries as a safe and bio-friendly alternative.
BIOREMEDIATION JOURNAL
(2022)
Article
Marine & Freshwater Biology
Ali Naseri, Mostafa Noroozi, Younes Asri, Alireza Iranbakhsh, Sara Saadatmand, Ehsan Atazadeh
Summary: The taxonomic composition of the diatom flora in the Taleghan River and reservoir in Iran was studied, and a total of 167 taxa belonging to 49 genera and 27 families were identified. The most abundant genera were Nitzschia, Navicula, Cymbella, and Gomphonema. Canonical Correspondence Analysis revealed that temperature, NO32-, salinity, turbidity, EC, Si, and DO were the most significant environmental variables impacting diatom assemblages in the river.
Article
Veterinary Sciences
F. Adami Ghamsari, M. Tajabadi Ebrahimi, M. Bagheri Varzaneh, A. Iranbakhsh, A. Akhavan Sepahi
Summary: Using organic adsorbents containing Lactobacillus bacteria and yeast cell wall is an effective strategy to reduce the toxicity of mycotoxins in dairy cow's diet. The addition of the organic adsorbent significantly improved milk production, total serum protein, and albumin levels, while reducing somatic cell count and serum urea levels. There were also significant decreases in white blood cell and lymphocyte counts after feeding with the adsorbent. Overall, the organic adsorbent improved the physical condition and health of the dairy cows.
JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY
(2022)
Article
Plant Sciences
Maryam Asadollahi, Alireza Iranbakhsh, Rahim Ahmadvand, Mostafa Ebadi, Iraj Mehregan
Summary: This study aims to evaluate the transcriptional responses of aquaporins (AQPs) to mycorrhizal inoculation and/or water deficit in wheat, and clarify the role of arbuscular mycorrhizal symbiosis in water homeostasis. The results showed that both water deficit and mycorrhizal inoculation have different impacts on the expression of AQPs, with a synergistic effect. The overexpression of TaNIP1-10, TaNIP3-3, and TaNIP3-4 genes was mainly triggered by mycorrhizal inoculation.
PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS
(2023)
Article
Plant Sciences
Setareh Azgomi, Alireza Iranbakhsh, Ahmad Majd, Mostafa Ebadi, Zahra Oraghi Ardebili
Summary: Exposure to different sound vibrations, such as music and noise, can stimulate the defense system of plants and trigger various biological responses. This study examined the effects of Iranian music, rock music, and urban/traffic noise on Satureja hortensis L. plants, and found that all acoustic treatments promoted germination, growth, and biomass accumulation. The treatments also increased the activity of certain enzymes and concentrations of phenolic compounds, and induced changes in gene expression and tissue differentiation. The findings suggest that rhythmic and non-rhythmic sounds can activate different metabolic pathways in plants.
THEORETICAL AND EXPERIMENTAL PLANT PHYSIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Zahra Ghaffarzadeh, Alireza Iranbakhsh, Mostafa Ebadi
Summary: This study found that the use of nFe significantly increased the root and shoot biomass of basil plants, while also more effectively enriching tissues with Fe and Zn. The nFe treatment also significantly increased Fe concentration in leaves and roots, and promoted the increase of peroxidase and phenylalanine ammonia-lyase enzyme activity in leaves.
JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
(2022)
Article
Plant Sciences
Fereshteh Sadat Seddighinia, Alireza Iranbakhsh, Zahra Oraghi Ardebili, Saman Soleimanpour
Summary: Recent studies on the behaviors of Momordica charantia following supplementation with multi-walled carbon nanotubes (CNT) and seed priming with cold plasma treatments showed significant improvement in early growth and performance of the plant. The treatments mediated variations in gene transcriptions and led to increased concentrations of beta-carotene and zeaxanthin. Additionally, there were significant positive correlations between the expression of target genes and concentrations of carotenoids, providing a theoretical basis for potential applications in the food, pharmaceutical, and agricultural industries.
JOURNAL OF APPLIED BOTANY AND FOOD QUALITY
(2021)