Alogliptin attenuates cyclophosphamide-induced nephrotoxicity: a novel therapeutic approach through modulating MAP3K/JNK/SMAD3 signaling cascade

Astragaloside IV Synergizes with Ferulic Acid to Alleviate Hepatic Fibrosis in Bile Duct-Ligated Cirrhotic Rats

(2020) Xue-Mei Zhao et al.   DIGESTIVE DISEASES AND SCIENCES

Effects of nitrite graded doses on hepatotoxicity and nephrotoxicity, histopathological alterations, and activation of apoptosis in adult rats

(2020) Nagla A. El-Nabarawy et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

LCZ696 (sacubitril/valsartan) protects against cyclophosphamide-induced testicular toxicity in rats: Role of neprilysin inhibition and lncRNA TUG1 in ameliorating apoptosis

(2020) Rania M. Salama et al.   TOXICOLOGY

The JNK Signaling Pathway in Inflammatory Skin Disorders and Cancer

(2020) Manel B. Hammouda et al.   Cells

Daratumumab, bortezomib, cyclophosphamide and dexamethasone in newly diagnosed and relapsed multiple myeloma: LYRA study

(2019) Habte Yimer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney

(2019) Haifa A.S. ALHaithloul et al.   BIOMEDICINE & PHARMACOTHERAPY

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

(2019) Mengjie Jiang et al.   Frontiers in Pharmacology

Glucagon-like peptide 1 (GLP-1)

(2019) T.D. Müller et al.   Molecular Metabolism

Zinc/alogliptin combination attenuates testicular toxicity induced by doxorubicin in rats: Role of oxidative stress, apoptosis and TGF-β1/NF-κB signaling

(2018) Ahmed M. Kabel   BIOMEDICINE & PHARMACOTHERAPY

Naringin protects against cyclophosphamide-induced hepatotoxicity and nephrotoxicity through modulation of oxidative stress, inflammation, apoptosis, autophagy, and DNA damage

(2018) Cuneyt Caglayan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis

(2018) Isabel Fabregat et al.   Frontiers in Oncology

Inhibition of NF-κB/TNF-α pathway may be involved in the protective effect of resveratrol against cyclophosphamide-induced multi-organ toxicity

(2017) Azza A. El-Sheikh et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Renoprotective effects of a dipeptidyl peptidase 4 inhibitor in a mouse model of progressive renal fibrosis

(2017) Takahiro Uchida et al.   RENAL FAILURE

Alogliptin, a Dipeptidyl Peptidase‐4 Inhibitor, Alleviates Atrial Remodeling and Improves Mitochondrial Function and Biogenesis in Diabetic Rabbits

(2017) Xiaowei Zhang et al.   Journal of the American Heart Association

Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes

(2017) Cristina Mega et al.   Journal of Diabetes Research

The JNK Signaling Pathway in Renal Fibrosis

(2017) Keren Grynberg et al.   Frontiers in Physiology

Dietary oxidized tyrosine (O-Tyr) stimulates TGF-β1-induced extracellular matrix production via the JNK/p38 signaling pathway in rat kidneys

(2016) Zhuqing Leslie Li et al.   AMINO ACIDS

The effects of PM10 on electrocardiogram parameters, blood pressure and oxidative stress in healthy rats: the protective effects of vanillic acid

(2016) Mahin Dianat et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The mechanisms of cyclophosphamide-induced testicular toxicity and the protective agents

(2016) Emad Ghobadi et al.   Expert Opinion on Drug Metabolism & Toxicology

Low-Dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor–Negative Early Breast Cancer: International Breast Cancer Study Group Trial 22-00

(2016) Marco Colleoni et al.   JOURNAL OF CLINICAL ONCOLOGY

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Diallyl Disulfide Prevents Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats through the Inhibition of Oxidative Damage, MAPKs, and NF-κB Pathways

(2015) Sung Hwan Kim et al.   Biomolecules & Therapeutics

Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition

(2015) Sen Shi et al.   KIDNEY INTERNATIONAL

The dipeptidyl peptidase-IV inhibitor inhibits the expression of vascular adhesion molecules and inflammatory cytokines in HUVECs via Akt- and AMPK-dependent mechanisms

(2015) Hwan-Jin Hwang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Molecular Mechanisms of Acrolein Toxicity: Relevance to Human Disease

(2015) Akshata Moghe et al.   TOXICOLOGICAL SCIENCES

Sitagliptin protects rat kidneys from acute ischemia-reperfusion injury via upregulation of GLP-1 and GLP-1 receptors

(2014) Meng-wei Chang et al.   ACTA PHARMACOLOGICA SINICA

Melittin Inhibits TGF-β-Induced Pro-Fibrotic Gene Expression Through the Suppression of the TGFβRII-Smad, ERK1/2 and JNK-Mediated Signaling Pathway

(2014) Su-Hyun Park et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Vildagliptin Restores Renal Myogenic Function and Attenuates Renal Sclerosis Independently of Effects on Blood Glucose or Proteinuria in Zucker Diabetic Fatty Rat

(2014) Peter Vavrinec et al.   Current Vascular Pharmacology

Dexmedetomidine Inhibits Tumor Necrosis Factor-Alpha and Interleukin 6 in Lipopolysaccharide-Stimulated Astrocytes by Suppression of c-Jun N-Terminal Kinases

(2014) Xiaobao Zhang et al.   INFLAMMATION

Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals

(2014) Catarina Marques et al.   MEDIATORS OF INFLAMMATION

Inflammatory processes in renal fibrosis

(2014) Xiao-Ming Meng et al.   Nature Reviews Nephrology

Protective effects of lipoic acid and mesna on cyclophosphamide-induced haemorrhagic cystitis in mice

(2013) Jianbo Song et al.   CELL BIOCHEMISTRY AND FUNCTION

Cyclophosphamide as a first-line therapy in LGL leukemia

(2013) A Moignet et al.   LEUKEMIA

Glucagon-Like Peptide-1 Counteracts Oxidative Stress-Dependent Apoptosis of Human Cardiac Progenitor Cells by Inhibiting the Activation of the c-Jun N-terminal Protein Kinase Signaling Pathway

(2012) L. Laviola et al.   ENDOCRINOLOGY

A Crosstalk between the Smad and JNK Signaling in the TGF-β-Induced Epithelial-Mesenchymal Transition in Rat Peritoneal Mesothelial Cells

(2012) Qinghua Liu et al.   PLoS One

TGF-β/Smad Signaling in Kidney Disease

(2012) Hui Y. Lan et al.   SEMINARS IN NEPHROLOGY

Novel Biological Action of the Dipeptidylpeptidase-IV Inhibitor, Sitagliptin, as a Glucagon-Like Peptide-1 Secretagogue

(2011) Ganesh V. Sangle et al.   ENDOCRINOLOGY

The cyclophosphamide metabolite, acrolein, induces cytoskeletal changes and oxidative stress in Sertoli cells

(2011) Feng Liu et al.   MOLECULAR BIOLOGY REPORTS

Gene expression profile of residual breast cancer after doxorubicin and cyclophosphamide neoadjuvant chemotherapy

(2009) Koike Folgueira   ONCOLOGY REPORTS