Predicting functional and regulatory divergence of a drug resistance transporter gene in the human malaria parasite

Influence networks based on coexpression improve drug target discovery for the development of novel cancer therapeutics

(2014) Nadia M Penrod et al.   BMC Systems Biology

Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism

(2014) Ian A. Lewis et al.   PLoS Genetics

Key genes for modulating information flow play a temporal role as breast tumor coexpression networks are dynamically rewired by letrozole

(2013) Nadia M Penrod et al.   BMC Medical Genomics

Epigenetic epistatic interactions constrain the evolution of gene expression

(2013) S. Park et al.   Molecular Systems Biology

Emerging artemisinin resistance in the border areas of Thailand

(2013) Kesara Na-Bangchang et al.   Expert Review of Clinical Pharmacology

A single source k-shortest paths algorithm to infer regulatory pathways in a gene network

(2012) Yu-Keng Shih et al.   BIOINFORMATICS

Beyond differential expression: the quest for causal mutations and effector molecules

(2012) Nicholas J Hudson et al.   BMC GENOMICS

CCR4-Associated Factor 1 Coordinates the Expression of Plasmodium falciparum Egress and Invasion Proteins

(2011) Bharath Balu et al.   EUKARYOTIC CELL

Predicting selective drug targets in cancer through metabolic networks

(2011) O. Folger et al.   Molecular Systems Biology

Predicting mutation outcome from early stochastic variation in genetic interaction partners

(2011) Alejandro Burga et al.   NATURE

Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets

(2011) J. Yuan et al.   SCIENCE

Fitness Trade-Offs and Environmentally Induced Mutation Buffering in Isogenic C. elegans

(2011) M. O. Casanueva et al.   SCIENCE

Coupled Evolution of Transcription and mRNA Degradation

(2011) Mally Dori-Bachash et al.   PLOS BIOLOGY

A decade of epigenetic research in Toxoplasma gondii

(2010) Stacy E. Dixon et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The Apicomplexan AP2 family: Integral factors regulating Plasmodium development

(2010) Heather J. Painter et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network

(2010) Germán Plata et al.   Molecular Systems Biology

From ‘differential expression’ to ‘differential networking’ – identification of dysfunctional regulatory networks in diseases

(2010) Alberto de la Fuente   TRENDS IN GENETICS

Need-Based Up-Regulation of Protein Levels in Response to Deletion of Their Duplicate Genes

(2010) Alexander DeLuna et al.   PLOS BIOLOGY

Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite

(2010) Tracey L. Campbell et al.   PLoS Pathogens

Histone Deacetylases Play a Major Role in the Transcriptional Regulation of the Plasmodium falciparum Life Cycle

(2010) Balbir K. Chaal et al.   PLoS Pathogens

H2A.Z Demarcates Intergenic Regions of the Plasmodium falciparum Epigenome That Are Dynamically Marked by H3K9ac and H3K4me3

(2010) Richárd Bártfai et al.   PLoS Pathogens

Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

(2009) Guangan Hu et al.   NATURE BIOTECHNOLOGY

Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

(2009) R. E. Martin et al.   SCIENCE

A Differential Wiring Analysis of Expression Data Correctly Identifies the Gene Containing the Causal Mutation

(2009) Nicholas J. Hudson et al.   PLoS Computational Biology

MADIBA: A web server toolkit for biological interpretation of Plasmodium and plant gene clusters

(2008) Philip J Law et al.   BMC GENOMICS

A verapamil-sensitive chloroquine-associated H+ leak from the digestive vacuole in chloroquine-resistant malaria parasites

(2008) A. M. Lehane et al.   JOURNAL OF CELL SCIENCE

Exposing the fitness contribution of duplicated genes

(2008) Alexander DeLuna et al.   NATURE GENETICS

Widespread Genetic Incompatibility in C. Elegans Maintained by Balancing Selection

(2008) H. S. Seidel et al.   SCIENCE

Regulatory Hotspots in the Malaria Parasite Genome Dictate Transcriptional Variation

(2008) Joseph M Gonzales et al.   PLOS BIOLOGY