Redox-Resistant SERCA Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload-Induced Myocardial Failure in Mice

Genetically targeted fluorescent probes reveal dynamic calcium responses to adrenergic signaling in multiple cardiomyocyte compartments

(2019) Ivan Luptak et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial oxidative stress induces leaky ryanodine receptor during mechanical ventilation

(2019) Haikel Dridi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease

(2016) Aaron L. Sverdlov et al.   Journal of the American Heart Association

Mitochondrial calcium overload is a key determinant in heart failure

(2015) Gaetano Santulli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload

(2014) Fuzhong Qin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Glutathione Adducts on Sarcoplasmic/Endoplasmic Reticulum Ca2+ATPase Cys-674 Regulate Endothelial Cell Calcium Stores and Angiogenic Function as Well as Promote Ischemic Blood Flow Recovery

(2014) Melissa D. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome

(2012) Evangelia G. Kranias et al.   CIRCULATION RESEARCH

Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress

(2011) Dao-Fu Dai et al.   CARDIOVASCULAR RESEARCH

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)

(2011) Mariell Jessup et al.   CIRCULATION

Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure

(2011) Dao-Fu Dai et al.   CIRCULATION RESEARCH

Short Communication: Oxidative Posttranslational Modifications Mediate Decreased SERCA Activity and Myocyte Dysfunction in Gαq-Overexpressing Mice

(2010) Steve Lancel et al.   CIRCULATION RESEARCH

Redox-mediated reciprocal regulation of SERCA and Na+–Ca2+ exchanger contributes to sarcoplasmic reticulum Ca2+ depletion in cardiac myocytes

(2010) Gabriela M. Kuster et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of Left Ventricular Volume Overload on Mitochondrial and Death-Receptor–Mediated Apoptotic Pathways in the Transition to Heart Failure

(2009) Narain Moorjani et al.   AMERICAN JOURNAL OF CARDIOLOGY

Nitroxyl Activates SERCA in Cardiac Myocytes via Glutathiolation of Cysteine 674

(2009) Steve Lancel et al.   CIRCULATION RESEARCH

Cardiac-Specific Overexpression of Catalase Identifies Hydrogen Peroxide-Dependent and -Independent Phases of Myocardial Remodeling and Prevents the Progression to Overt Heart Failure in Gαq-Overexpressing Transgenic Mice

(2009) Fuzhong Qin et al.   Circulation-Heart Failure

Calcium Elevation in Mitochondria Is the Main Ca2+Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening

(2009) Heidi K. Baumgartner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Modification of Ryanodine Receptors Contributes to Sarcoplasmic Reticulum Ca 2+ Leak in Chronic Heart Failure

(2008) Dmitry Terentyev et al.   CIRCULATION RESEARCH