Thrombin-Par1 signaling axis disrupts COP9 signalosome subunit 3-mediated ABCA1 stabilization in inducing foam cell formation and atherogenesis

The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein

(2019) Natasha Zarich et al.   Oncogenesis

Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases

(2019) Milic et al.   Biomolecules

Smooth muscle cell fate and plasticity in atherosclerosis

(2018) Sima Allahverdian et al.   CARDIOVASCULAR RESEARCH

PKCθ via Activating Transcription Factor 2-Mediated CD36 Expression and Foam Cell Formation of Ly6ChiCells Contributes to Atherosclerosis

(2018) Somasundaram Raghavan et al.   CIRCULATION

LIM and cysteine-rich domains 1 is required for thrombin-induced smooth muscle cell proliferation and promotes atherogenesis

(2018) Jagadeesh Janjanam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3–mediated degradation of the ABCA1 transporter

(2018) Somasundaram Raghavan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Corrected and Republished from: The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability

(2018) Justyna Korczeniewska et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo

(2017) Yaw Asare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein A-1 binding protein promotes macrophage cholesterol efflux by facilitating apolipoprotein A-1 binding to ABCA1 and preventing ABCA1 degradation

(2016) Min Zhang et al.   ATHEROSCLEROSIS

Deubiquitination and Stabilization of PD-L1 by CSN5

(2016) Seung-Oe Lim et al.   CANCER CELL

A Novel Mutation in ABCA1 Gene Causing Tangier Disease in an Italian Family with Uncommon Neurological Presentation

(2016) Marco Ceccanti et al.   Frontiers in Neurology

CSN-associated USP48 confers stability to nuclear NF-κB/RelA by trimming K48-linked Ub-chains

(2015) Katrin Schweitzer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice

(2015) LinZhang Huang et al.   JOURNAL OF LIPID RESEARCH

Molecular Mechanisms of Cellular Cholesterol Efflux

(2014) Michael C. Phillips   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

(2013) Marit Westerterp et al.   CIRCULATION RESEARCH

Endothelial CSN5 impairs NF-κB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions

(2013) Yaw Asare et al.   THROMBOSIS AND HAEMOSTASIS

EphA2 Activation Promotes the Endothelial Cell Inflammatory Response

(2012) Steven Daniel Funk et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholesterol Efflux and Atheroprotection

(2012) Robert S. Rosenson et al.   CIRCULATION

Proteasomal Inhibition Promotes ATP-Binding Cassette Transporter A1 (ABCA1) and ABCG1 Expression and Cholesterol Efflux From Macrophages In Vitro and In Vivo

(2011) Masatsune Ogura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Liver X Receptor Signaling Pathways and Atherosclerosis

(2010) Anna C. Calkin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The COP9 signalosome controls ubiquitinylation of ABCA1

(2009) Yuya Azuma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

HDL, ABC Transporters, and Cholesterol Efflux: Implications for the Treatment of Atherosclerosis

(2008) Alan R. Tall et al.   Cell Metabolism

Activation of Cdk2 Stimulates Proteasome-dependent Truncation of Tyrosine Phosphatase SHP-1 in Human Proliferating Intestinal Epithelial Cells

(2008) Mélanie Simoneau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY