Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis

Methylation of C/EBPα by PRMT1 inhibits its tumor suppressive function in breast cancer

(2019) Li-ming Liu et al.   CANCER RESEARCH

PRMTs and Arginine Methylation: Cancer’s Best-Kept Secret?

(2019) James Jarrold et al.   TRENDS IN MOLECULAR MEDICINE

Revisiting the protomotive vectorial motion of F0-ATPase

(2019) Chen Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine

(2018) Jia Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

(2018) Lixin Wan et al.   MOLECULAR CELL

O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2

(2018) Pei-Wen Lo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis

(2018) Talha Anwar et al.   Nature Communications

CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion

(2017) Xin Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arginine Methylation: The Coming of Age

(2017) Roméo S. Blanc et al.   MOLECULAR CELL

Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation

(2016) Yan Wang et al.   CANCER RESEARCH

The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer

(2016) Zhongwei Li et al.   CELL DEATH AND DIFFERENTIATION

Targeting EZH2 in cancer

(2016) Kimberly H Kim et al.   NATURE MEDICINE

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

(2016) Neil Justin et al.   Nature Communications

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

(2015) Hsin-Wei Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression

(2015) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors

(2015) Daniel Zingg et al.   Nature Communications

Arginine methylation of hnRNPK negatively modulates apoptosis upon DNA damage through local regulation of phosphorylation

(2014) Jen-Hao Yang et al.   NUCLEIC ACIDS RESEARCH

O-GlcNAcylation regulates EZH2 protein stability and function

(2014) C.-S. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming

(2013) Neha Tiwari et al.   CANCER CELL

Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation

(2013) Clare C Davies et al.   EMBO JOURNAL

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

EZH2 Promotes Expansion of Breast Tumor Initiating Cells through Activation of RAF1-β-Catenin Signaling

(2011) Chun-Ju Chang et al.   CANCER CELL

Arginine methylation-dependent regulation of ASK1 signaling by PRMT1

(2011) J-H Cho et al.   CELL DEATH AND DIFFERENTIATION

Cyclin-dependent Kinase 1 (CDK1)-mediated Phosphorylation of Enhancer of Zeste 2 (Ezh2) Regulates Its Stability

(2011) Susan C. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling

(2011) B Cha et al.   ONCOGENE

Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt

(2011) J.-i. Sakamaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Substrate Profiling of PRMT1 Reveals Amino Acid Sequences That Extend Beyond the “RGG” Paradigm†

(2008) Whitney L. Wooderchak et al.   BIOCHEMISTRY

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL