TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα

Knockdown of TRIM22 Relieves Oxygen–Glucose Deprivation/Reoxygenation-Induced Apoptosis and Inflammation Through Inhibition of NF-κB/NLRP3 Axis

(2020) Chongyang Kang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation

(2019) Kaikai Ding et al.   ONCOGENE

Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB Signaling

(2019) Jianxiong Ji et al.   CLINICAL CANCER RESEARCH

Patient-Derived Glioma Models: From Patients to Dish to Animals

(2019) Cintia Carla da Hora et al.   Cells

TRIM22 regulates macrophage autophagy and enhances Mycobacterium tuberculosis clearance by targeting the nuclear factor-multiplicity κB/beclin 1 pathway

(2018) Jun Lou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The p53 Pathway in Glioblastoma

(2018) Ying Zhang et al.   Cancers

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

Ubiquitin chain diversity at a glance

(2016) Masato Akutsu et al.   JOURNAL OF CELL SCIENCE

Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide

(2015) N. M. Mansour et al.   CANCER RESEARCH

Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy

(2015) Kirk E. Cahill et al.   NEURO-ONCOLOGY

TRIM22 can activate the noncanonical NF-κB pathway by affecting IKKα

(2014) Hui Qiu et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO

(2014) Juan Liu et al.   NATURE IMMUNOLOGY

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation

(2013) Hui Qiu et al.   VIROLOGICA SINICA

Ubiquitination in signaling to and activation of IKK

(2012) Zhijian J. Chen   IMMUNOLOGICAL REVIEWS

TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets

(2012) Libing Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of tripartite motif-containing 22 (TRIM22) as a novel NF-κB activator

(2011) Shanshan Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRIM40 promotes neddylation of IKK  and is downregulated in gastrointestinal cancers

(2011) K. Noguchi et al.   CARCINOGENESIS

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

(2011) Jixiao Niu et al.   EMBO JOURNAL

TRIM22 Inhibits HIV-1 Transcription Independently of Its E3 Ubiquitin Ligase Activity, Tat, and NF- B-Responsive Long Terminal Repeat Elements

(2011) A. Kajaste-Rudnitski et al.   JOURNAL OF VIROLOGY

Ubiquitin becomes ubiquitous in cancer

(2010) Dingding Shi et al.   CANCER BIOLOGY & THERAPY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Expanding role of ubiquitination in NF-κB signaling

(2010) Siqi Liu et al.   CELL RESEARCH

B30.2/SPRY domain in tripartite motif-containing 22 is essential for the formation of distinct nuclear bodies

(2009) Gayathri Sivaramakrishnan et al.   FEBS LETTERS

Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain

(2009) Bo Gao et al.   HEPATOLOGY

TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus

(2009) P. Eldin et al.   JOURNAL OF GENERAL VIROLOGY

Identification of TRIM22 as a RING finger E3 ubiquitin ligase

(2008) Zhijian Duan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22

(2008) Stephen D. Barr et al.   PLoS Pathogens