Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma

Longitudinal NK cell kinetics and cytotoxicity in children with neuroblastoma enrolled in a clinical phase II trial

(2020) Rosa Nguyen et al.   Journal for ImmunoTherapy of Cancer

A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies

(2019) Yuanbin Song et al.   Nature Communications

A phase II clinical trial of adoptive transfer of haploidentical natural killer cells for consolidation therapy of pediatric acute myeloid leukemia

(2019) Rosa Nguyen et al.   Journal for ImmunoTherapy of Cancer

Interleukin-15 Enhances Anti-GD2 Antibody-Mediated Cytotoxicity in an Orthotopic PDX Model of Neuroblastoma

(2019) Rosa Nguyen et al.   CLINICAL CANCER RESEARCH

Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma

(2019) Julie R. Park et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma

(2019) Wayne L. Furman et al.   CLINICAL CANCER RESEARCH

Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

(2019) Chao Yang et al.   Nature Communications

The role of interleukin-2, all-trans retinoic acid, and natural killer cells: surveillance mechanisms in anti-GD2 antibody therapy in neuroblastoma

(2018) Rosa Nguyen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice

(2018) Adeline Crinier et al.   IMMUNITY

Orthotopic patient-derived xenografts of paediatric solid tumours

(2017) Elizabeth Stewart et al.   NATURE

Development and characterization of a human orthotopic neuroblastoma xenograft

(2015) Elizabeth Stewart et al.   DEVELOPMENTAL BIOLOGY

Cell biological steps and checkpoints in accessing NK cell cytotoxicity

(2014) Emily M Mace et al.   IMMUNOLOGY AND CELL BIOLOGY

Development and function of human innate immune cells in a humanized mouse model

(2014) Anthony Rongvaux et al.   NATURE BIOTECHNOLOGY

Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine

(2013) Anthony Rongvaux et al.   Annual Review of Immunology

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

The Promise of Patient-Derived Xenografts: The Best Laid Plans of Mice and Men

(2012) S. Kopetz et al.   CLINICAL CANCER RESEARCH

Monocytes derived from humanized neonatal NOD/SCID/IL2Rγnull mice are phenotypically immature and exhibit functional impairments

(2012) Christian Gille et al.   HUMAN IMMUNOLOGY

A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer

(2011) Joaquim Calbo et al.   CANCER CELL

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence

(2010) T. Strowig et al.   BLOOD

AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3

(2010) M Wunderlich et al.   LEUKEMIA