Article
Medicine, General & Internal
Maria Damps, Elzbieta Byrska-Maciejasz, Malgorzata Kowalska, Jowita Rosada-Kurasinska, Beata Rybojad, Joanna Sordyl, Marzena Zielinska, Alicja Bartkowska-Sniatkowska
Summary: This study analyzed children admitted to PICUs due to severe SARS-CoV-2 infection and found that children with comorbidities are more likely to develop severe symptoms and respiratory failure, while high values of aspartate aminotransferase (AST) are associated with poor prognosis.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Kailey A. Remien, Justin Z. Amarin, Christopher M. Horvat, Ryan A. Nofziger, Christopher K. Page-Goertz, James B. Besunder, Brittany K. Potts, Michael L. Forbes, Natasha Halasa, Jonathan H. Pelletier
Summary: This study analyzed the changes in bronchiolitis admissions at US children's hospitals from 2010 to 2023. The study found that there was a transient decrease in bronchiolitis hospitalizations during the COVID-19 pandemic era, followed by a marked increase. Patients admitted during the pandemic era were older and more likely to be admitted to an ICU. These findings suggest that bronchiolitis seasonality has not returned to pre-pandemic patterns, and US hospitals should prepare for atypical timing in the future.
Article
Respiratory System
Kyungmin Huh, Young-Eun Kim, Wonjun Ji, Dong Wook Kim, Eun-Joo Lee, Jong-Hun Kim, Ji-Man Kang, Jaehun Jung
Summary: The study found that the implementation of non-pharmaceutical interventions during COVID-19 substantially reduced hospitalisations for pneumonia, influenza, COPD, and asthma. Admissions for COPD and asthma were significantly lower compared to the preceding years.
Article
Public, Environmental & Occupational Health
Lorenz A. Kapsner, Marvin O. Kampf, Susanne A. Seuchter, Julian Gruendner, Christian Gulden, Sebastian Mate, Jonathan M. Mang, Christina Schuettler, Noemi Deppenwiese, Linda Krause, Daniela Zoeller, Julien Balig, Timo Fuchs, Patrick Fischer, Christian Haverkamp, Martin Holderried, Gerhard Mayer, Holger Stenzhorn, Ana Stolnicu, Michael Storck, Holger Storf, Jochen Zohner, Oliver Kohlbacher, Adam Strzelczyk, Juergen Schuettler, Till Acker, Martin Boeker, Udo X. Kaisers, Hans A. Kestler, Hans-Ulrich Prokosch
Summary: The COVID-19 pandemic significantly reduced hospital admissions in German university hospitals, even for critical care or emergency conditions. Future studies are required to explore how appropriate medical care for critically ill patients can be maintained during a pandemic.
FRONTIERS IN PUBLIC HEALTH
(2021)
Review
Respiratory System
Carina S. B. Tyrrell, Oliver T. Mytton, Sarah Gentry, Molly Thomas-Meyer, John Lee Y. Allen, Antony A. Narula, Brendan McGrath, Martin Lupton, Jo Broadbent, Aliko Ahmed, Angelique Mavrodaris, Anees Ahmed Abdul Pari
Summary: The surge in severe COVID-19 cases has led to the triaging of ICU admissions, with significant variability in guidelines globally. Various themes such as ethical frameworks, criteria for admission and discharge, and decision-making processes are covered, highlighting the lack of consensus in resource allocation during the pandemic.
Article
Virology
Christian Tanislav, Karel Kostev
Summary: Research found that during the COVID-19 pandemic, there was a significant decrease in non-COVID-19 related respiratory tract and gastrointestinal infections, especially influenza and bacterial infections. Conversely, relatively rare viral pneumonia showed a significant increase in diagnoses.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Psychiatry
Jaksa Vukojevic, Natasa Duran, Nikola Zaja, Jelena Susac, Mario Sekerija, Aleksandar Savic
Summary: By comparing the medical records of the Spanish flu and the COVID-19 pandemic, it was found that both did not lead to an increase in emergency psychiatric admissions, which is consistent with research findings in Europe.
PSYCHIATRY RESEARCH
(2021)
Article
Pediatrics
Alana K. Otto, Jessica M. Jary, Julie Sturza, Catherine A. Miller, Natalie Prohaska, Terrill Bravender, Jessica Van Huysse
Summary: During the COVID-19 pandemic, medical admissions related to restrictive eating disorders significantly increased among adolescents. Despite similar demographics of admitted patients before and during the pandemic, there was a marked increase in the number of admissions.
Article
Medicine, General & Internal
Cameron Ghafil, Kazuhide Matsushima, Li Ding, Reynold Henry, Kenji Inaba
Summary: Analyzing trauma admissions in Los Angeles County during the COVID-19 pandemic revealed significant changes in injury patterns and admission trends, especially in the types of traumas seen. The study showed a transient decrease in trauma volume at the beginning of the pandemic, followed by a quick return to baseline levels.
Article
Infectious Diseases
Jasmin Bogli, Sabine Gusewell, Rita Strassle, Christian R. Kahlert, Werner C. Albrich
Summary: The study found that the COVID-19 pandemic and associated protective measures had a significant impact on children's health, particularly with decreases in hospital admissions for respiratory infections after the introduction of strict measures followed by a rebound after restrictions were loosened.
Article
Emergency Medicine
Sara Nourazari, Samuel R. Davis, Rachel Granovsky, Randolph Austin, Dean J. Straff, Joshua W. Joseph, Leon D. Sanchez
Summary: The study shows a significant decrease in hospital admissions through EDs during the COVID-19 pandemic, with notable drops in admissions for chronic respiratory conditions and non-orthopedic needs. Women, children, and patients with Medicare or without insurance experienced particularly acute decreases.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Pediatrics
Beatriz Ramos La Cuey, Neus Saloni-Gomez, Andrea Ilundain Lopez de Munain, Alejandro Fernandez-Montero, Natividad Viguria, Leyre Lopez Fernandez, Mercedes Herranz Aguirre, Ainhoa Iceta, Laura Moreno-Galarraga
Summary: Since the start of the COVID-19 pandemic, there have been significant changes in the cycling patterns of pediatric pathologies. This study examines the long-term effects of COVID-19 on pediatric non-COVID admissions, specifically the resurgence of respiratory illnesses. The findings show that the pandemic has had a significant impact on the use and nature of pediatric health services.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Computer Science, Artificial Intelligence
Nurul Izrin Md Saleh, Hadhrami Ab Ghani, Zairul Jilani
Summary: This paper proposes a method that uses Formal Concept Analysis to explain a machine learning model applied to hospital admission data of COVID-19 cases. This approach can increase transparency in decision-making and optimize the use of ML in real-world applications.
ARTIFICIAL INTELLIGENCE IN MEDICINE
(2022)
Article
Multidisciplinary Sciences
Anang Endaryanto, Arlina Dewi, Kusbaryanto, Ricardo Adrian Nugraha
Summary: The COVID-19 pandemic has led to a decrease in hospitalizations for non-COVID respiratory conditions, with an increase in disease severity among child patients and a decrease in adults. Costs and insurance payments have increased, but hospital profits have decreased due to insurance payments not keeping up with the cost of care.
Article
Psychiatry
Brendon Lin, Anna Costakis, Majnu John, Howard Linder
Summary: This study compares psychiatric hospitalization rates between patients receiving in-person psychiatric care and virtual psychiatric care during the COVID-19 pandemic. The results show that there was a significant decrease in hospitalization rates between 2019 and 2020, suggesting a decrease in admissions associated with the adoption of telepsychiatry.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Cardiac & Cardiovascular Systems
Henry P. Foote, Christoph P. Hornik, Kevin D. Hill, Alexandre T. Rotta, Karan R. Kumar, Elizabeth J. Thompson
Summary: Complications from pulmonary hypertension are a major cause of morbidity and mortality in children with congenital heart disease (CHD) post-cardiopulmonary bypass surgery. The use of pulmonary vasodilator therapy after surgery is common, but the optimal target patient population, therapy choice, timing, and duration are unclear. This review identified 26 studies involving 42,971 children with CHD, and found that inhaled nitric oxide, iloprost, and sildenafil showed improved haemodynamics in specific cohorts of children with post-operative pulmonary hypertension. However, further research is needed to reduce post-operative morbidity and mortality.
CARDIOLOGY IN THE YOUNG
(2022)
Article
Pediatrics
Omar Alibrahim, Kyle J. Rehder, Andrew G. Miller, Alexandre T. Rotta
PEDIATRIC CLINICS OF NORTH AMERICA
(2022)
Letter
Critical Care Medicine
Pablo Cruces, Benjamin Erranz, Carlos Gonzalez, Franco Diaz
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Samer Abu-Sultaneh, Narayan Prabhu Iyer, Analia Fernandez, Michael Gaies, Sebastian Gonzalez-Dambrauskas, Justin Christian Hotz, Martin C. J. Kneyber, Yolanda M. Lopez-Fernandez, Alexandre T. Rotta, David K. Werho, Arun Kumar Baranwal, Bronagh Blackwood, Hannah J. Craven, Martha A. Q. Curley, Sandrine Essouri, Jose Roberto Fioretto, Silvia M. M. Hartmann, Philippe Jouvet, Steven Kwasi Korang, Gerrard F. Rafferty, Padmanabhan Ramnarayan, Louise Rose, Lyvonne N. Tume, Elizabeth C. Whipple, Judith J. M. Wong, Guillaume Emeriaud, Christopher W. Mastropietro, Natalie Napolitano, Christopher J. L. Newth, Robinder G. Khemani
Summary: Pediatric-specific ventilator liberation guidelines are lacking and have led to unnecessary variation in methods used to assess readiness for extubation. An international panel of experts developed evidence-based recommendations for best practices related to pediatric ventilator liberation, including screening, spontaneous breathing trials, respiratory muscle strength assessment, and prevention of upper airway obstruction. However, most recommendations are conditional and based on low certainty of evidence.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Samer Abu-Sultaneh, Narayan Prabhu Iyer, Analia Fernandez, Michael Gaies, Sebastian Gonzalez-Dambrauskas, Justin Christian Hotz, Martin C. J. Kneyber, Yolanda M. Lopez-Fernandez, Alexandre T. Rotta, David K. Werho, Arun Kumar Baranwal, Bronagh Blackwood, Hannah J. Craven, Martha A. Q. Curley, Sandrine Essouri, Jose Roberto Fioretto, Silvia M. M. Hartmann, Philippe Jouvet, Steven Kwasi Korang, Gerrard F. Rafferty, Padmanabhan Ramnarayan, Louise Rose, Lyvonne N. Tume, Elizabeth C. Whipple, Judith Ju Ming Wong, Guillaume Emeriaud, Christopher W. Mastropietro, Natalie Napolitano, Christopher J. L. Newth, Robinder G. Khemani
Summary: This study aims to establish operational definitions for key elements related to pediatric ventilator liberation through a detailed literature review and consensus-based approaches. These definitions will reduce variability in research and quality improvement efforts, improve generalizability, and facilitate comparison.
Article
Immunology
Yvette N. N. Lowensteyn, Joukje E. E. Willemsen, Natalie I. I. Mazur, Nienke M. M. Scheltema, Nynke C. J. van Haastregt, Amber A. A. ten Buuren, Ichelle van Roessel, Dunja Scheepmaker, Harish Nair, Peter M. M. van de Ven, Louis J. J. Bont
Summary: This study provides the first global case series of children dying with nosocomial RSV infection. Infant-targeted immunization strategies in the future could prevent the majority of nosocomial RSV-related deaths. Although nosocomial RSV deaths are expected to occur at highest rates in low- and lower-middle-income countries (LMICs), the reported number of these deaths was low in these countries. Hospital-based surveillance is needed to capture the full burden of nosocomial RSV mortality in LMICs.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2023)
Letter
Critical Care Medicine
Pablo Cruces, Benjamin Erranz, Franco Diaz
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Editorial Material
Pediatrics
Alexandre T. Rotta, Omar Alibrahim
JORNAL DE PEDIATRIA
(2023)
Article
Critical Care Medicine
Guillaume Emeriaud, Marti Pons-odena, Anoopindar K. Bhalla, Steven L. Shein, Elizabeth Y. Killien, Vicent Alapont, Courtney Rowan, Florent Baudin, John C. Lin, Gabrielle Gregoire, Natalie Napolitano, Juan Mayordomo-Colunga, Franco Diaz, Pablo Cruces, Alberto Medina, Lincoln Smith, Robinder G. Khemani
Summary: This study aimed to describe the use of noninvasive ventilation (NIV) and its clinical outcomes in pediatric acute respiratory distress syndrome (PARDS).
PEDIATRIC CRITICAL CARE MEDICINE
(2023)
Article
Medicine, General & Internal
Alasdair Munro, Danilo Buonsenso, Sebastian Gonzalez-Dambrauskas, Robert C. Hughes, Sunil S. Bhopal, Pablo Vasquez-Hoyos, Muge Cevik, Maria Lucia Mesa Rubio, Damian Roland
BMJ EVIDENCE-BASED MEDICINE
(2023)
Article
Respiratory System
Narayan P. Iyer, Yolanda M. Lopez-Fernandez, Sebastian Gonzalez-Dambrauskas, Arun K. Baranwal, Justin C. Hotz, Meng Zhu, Yuan Zhang, Hannah J. Craven, Elizabeth C. Whipple, Samer Abu-Sultaneh, Robinder G. Khemani
Summary: In this study, the effectiveness of different corticosteroid regimens in preventing upper airway obstruction (UAO) and reintubation in children was compared. The results showed that early initiation of dexamethasone, ideally more than 12 hours before extubation, is more important than the dose in preventing UAO. However, there is no clear optimal regimen for preventing reintubation. Therefore, individualized steroid strategies should consider the potential adverse events associated with dexamethasone and the individual risk of UAO and reintubation.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Meeting Abstract
Critical Care Medicine
Bryan Combs, Steven Shein, Sebastian Gonzalez-Dambrauskas, Jose Colleti Junior, Pablo Vasquez-Hoyos, Arnaldo Barbosa, David Boothe, Jan Hau Lee, Donna Franklin, Steven Pon, Todd Karsies, Adrian Zurca
CRITICAL CARE MEDICINE
(2022)
Article
Pediatrics
Takaharu Karube, Theresa Goins, Todd J. Karsies, Samantha W. Gee
Summary: This study aimed to reduce avoidable delays in pediatric intensive care unit (PICU) discharge for patients with status asthmaticus by standardizing transfer criteria and implementing multidisciplinary strategies. The results showed a significant reduction in the time from transfer criteria fulfillment to discharge, as well as a decrease in readmissions for asthma exacerbations.
PEDIATRIC QUALITY & SAFETY
(2022)
