期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 160, 期 -, 页码 36-51出版社
ELSEVIER
DOI: 10.1016/j.addr.2020.10.009
关键词
Drug delivery; Tumor therapy; Peptide; Targeting; Stimulus-responsive
资金
- National Natural Science Foundation of China [21674084, 51833007, 51690152, 51988102]
- National Key Research and Development Program of China [2019YFA0905603]
Controlled nano-systems for drug delivery are designed to deliver therapeutical drugs to desirable sites on demand. Due to the diverse physiological functions of peptides, it is reasonable to introduce peptides into anti-tumor nano-system. The integration of peptides into nanomaterials has complementary advantages, which not only avoids the rapid degradation of peptides in vivo, but also improves the intelligence and functionality of the nano-system. We summarized the functional peptides with targeting and stimulus-responsive properties, and the present review outlined the most relevant and recent developed peptide-based multifunctional nanomaterials for tumor therapy. (C) 2020 Elsevier B.V. All rights reserved.
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