Multiple sclerosis risk variants regulate gene expression in innate and adaptive immune cells

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

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Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients

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METTL21B Is a Novel Human Lysine Methyltransferase of Translation Elongation Factor 1A: Discovery by CRISPR/Cas9 Knockout

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The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)

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The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years

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Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis

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Consensus Genome-Wide Expression Quantitative Trait Loci and Their Relationship with Human Complex Trait Disease

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Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

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LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants: Fig. 1.

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The immunogenetics of multiple sclerosis: A comprehensive review

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ImmVar project: Insights and design considerations for future studies of “healthy” immune variation

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eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference

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Identification of Myelin Transcription Factor 1 (MyT1) as a Subunit of the Neural Cell Type-specific Lysine-specific Demethylase 1 (LSD1) Complex

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Regulatory genomic regions active in immune cell types explain a large proportion of the genetic risk of multiple sclerosis

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Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

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Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

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Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

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Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes

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Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells

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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

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Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

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Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

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The many roles of the eukaryotic elongation factor 1 complex

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Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

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Using control genes to correct for unwanted variation in microarray data

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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

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Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

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