Review
Biochemistry & Molecular Biology
Ashley J. Ovens, John W. Scott, Christopher G. Langendorf, Bruce E. Kemp, Jonathan S. Oakhill, William J. Smiles
Summary: AMP-activated protein kinase (AMPK) plays a crucial role in adaptive responses to exercise, and its post-translational modifications extensively influence its activity, subcellular localization, nutrient interactions, and protein stability. Areas for further research include novel regulatory modifications of AMPK and improving characterization of these modifications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell Biology
Malgorzata Tokarska-Schlattner, Laurence Kay, Pascale Perret, Raffaella Isola, Stephane Attia, Frederic Lamarche, Cindy Tellier, Cecile Cottet-Rousselle, Amjad Uneisi, Isabelle Hininger-Favier, Marc Foretz, Herve Dubouchaud, Catherine Ghezzi, Christian Zuppinger, Benoit Viollet, Uwe Schlattner
Summary: AMPK, a key regulator of energy homeostasis, plays important roles in maintaining cardiac function under increased workload conditions. Deletion of AMPK genes in cardiomyocytes did not affect heart function under physiological conditions, but led to alterations in response to increased workload. AMPK deletion also resulted in decreased basal metabolic rate and locomotor activity, along with changes in cardiac mitochondrial function and bioenergetics.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Marine & Freshwater Biology
Jin Chen, Li Xu, Xue-Qing Zhang, Xue Liu, Zi-Xuan Zhang, Qiu-Mei Zhu, Jian-Yu Liu, Muhammad Omer Iqbal, Ning Ding, Chang-Lun Shao, Mei-Yan Wei, Yu-Chao Gu
Summary: Non-alcoholic steatohepatitis (NASH) is a leading cause of cirrhosis and hepatocellular carcinoma. A marine natural compound, candidusin A (CHNQD-0803), has been identified as a potent AMPK activator and a potential therapeutic candidate for NASH treatment.
MARINE LIFE SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Yafei Duan, Shimin Zeng, Zijun Lu, Xueming Dan, Zequan Mo, Yifu Xing, Jiasong Zhang, Yanwei Li
Summary: In this study, the effects of Microcystin-LR (MC-LR) on lipid metabolism and lipidomic responses in Litopenaeus vannamei hepatopancreas were investigated. The results showed that MC-LR exposure caused tissue damage and decreased the activities of several lipase isoenzymes in the hepatopancreas. Additionally, the relative gene expression levels of key genes involved in lipolysis, lipogenesis, and fatty acid beta-oxidation were increased. Lipidomic analysis revealed that MC-LR exposure resulted in increased levels of glycerophospholipids, sphingolipids, and cholesteryl ester, while the levels of phosphatidylinositol and triglyceride were decreased. These findings provide important insights into the effects of MC-LR on lipid metabolism and lipidomic homeostasis in shrimp hepatopancreas.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Biochemistry & Molecular Biology
Fiona M. Russell, David Grahame Hardie
Summary: AMP-activated protein kinase (AMPK) plays a crucial role in regulating cellular energy balance by promoting ATP production and inhibiting cell growth. It may restrain aberrant growth before tumorigenesis, but support the survival of cancer cells once cancer has arisen.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Xiaojie Lu, Yue Jing, Xiaofei Zhou, Naisheng Zhang, Jiandong Tai, Yongguo Cao
Summary: Bacillus licheniformis Zhengchangsheng (R) has been shown to inhibit obesity by regulating gut microbiota in obese mice, leading to improved body weight, fat accumulation, serum lipid profiles, inflammatory cytokines, and glucose and lipid metabolism. Additionally, it activates the AMP-activated protein kinase pathway, suggesting its potential in treating obesity and related metabolic diseases.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2021)
Article
Environmental Sciences
Zheng Luo, Yang Yu, Qian Zhang, Zhenning Bao, Jianhai Xiang, Fuhua Li
Summary: This study investigates the differences in gene expression between tolerant and susceptible families of Pacific white shrimp Litopenaeus vannamei under normal and high-salinity conditions. Results suggest that crustacyanins and serine proteases play important roles in shrimp tolerance to high salinity. The findings provide valuable information for understanding the mechanism of high-salinity tolerance and could contribute to the breeding of shrimp varieties with improved tolerance.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Cell Biology
Hongyan Ding, Yu Li, Wei Li, Huanqing Tao, Leihong Liu, Cai Zhang, Tao Kong, Shibin Feng, Jinchun Li, Xichun Wang, Jinjie Wu
Summary: The study found that EGCG can regulate hepatic lipid metabolism in canines by activating the AMPK signaling pathway and decreasing fat accumulation. Additionally, exogenous BML-275 can inhibit the effects of EGCG on lipid metabolism.
JOURNAL OF CELLULAR PHYSIOLOGY
(2021)
Article
Environmental Sciences
Miao Shi, Song Jiang, Shigui Jiang, Qibin Yang, Yundong Li, Falin Zhou
Summary: This study evaluated the stress resistance of Litopenaeus vannamei through family breeding and compared the tolerance of different families to high ammonia-N, high pH, and low salt stress. The population with a female parent from the United States showed stronger tolerance to stress compared to the population with a female parent from Thailand. The TM hybrid population exhibited heterosis in high ammonia-N and high pH tolerance, while family MM7 had strong low salt tolerance.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Oncology
Cheng Wang, Wencheng Zhang, Wenjing Xu, Zhaoyu Liu, Kai Huang
Summary: This study found that hepatic AMPK alpha 1 plays an essential role in maintaining iron homeostasis by regulating hepcidin through its interaction with PHD2. This discovery provides a new potential approach for treating iron disturbances in chronic diseases.
CLINICAL AND TRANSLATIONAL MEDICINE
(2022)
Article
Environmental Sciences
Zhongkai Wang, Yigeng Chen, Cong Wang, Nannan Zhao, Zhihao Zhang, Zhitong Deng, Yanting Cui, Renjie Wang, Yuquan Li
Summary: This study identified and characterized three types of AQPs in Litopenaeus vannamei and investigated their potential roles in osmoregulation. The expression levels of AQPs were significantly decreased under salinity stress, though the patterns varied among isoforms and tissues. Comparative transcriptome analysis revealed the involvement of aquaglyceroporin and amino acid metabolism related genes and pathways in the response to acute salinity changes in the intestine.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Chemistry, Applied
Qian Hong, Yu-Lei Chen, Duanquan Lin, Ru-Qing Yang, Kai-Yuan Cao, Ling-Jing Zhang, Yi-Ming Liu, Le-Chang Sun, Min-Jie Cao
Summary: In this study, the PPO gene from Litopenaeus vannamei (Lv-PPO) was cloned, expressed, and purified. The recombinant Lv-PPO (rLv-PPO) was shown to be biologically active and influenced by metal ions Cu2+ and Zn2+. A specific antibody against rLv-PPO was prepared, and the levels of PPO were found to be highest in the hemolymph of shrimp.
Article
Food Science & Technology
Wenkai Zhang, Li Kong, Zhen Zhong, Lezhen Lin, Jingen Li, Guodong Zheng
Summary: Short chain fatty acids (SCFAs) promote fatty acid 0-oxidation and browning in 3T3-L1 adipocytes by regulating the 03-AR/AMPKα signaling pathway. SCFAs reduce lipid accumulation and enhance mitochondrial biogenesis. They also up-regulate the expression of fatty acid 0-oxidation genes and brown adipocyte-specific factors.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Biochemistry & Molecular Biology
Yu-Hsu Chen, Kuang-Kai Hsueh, Pei-Wen Chu, Shau-Kwaun Chen
Summary: AMP-activated protein kinase (AMPK) is a critical metabolic regulator that affects immune cell functions such as macrophages and osteoclasts. AMPK plays a key role in promoting anti-inflammatory responses in macrophages and negatively regulating osteoclastogenesis.
JOURNAL OF CELLULAR BIOCHEMISTRY
(2022)
Article
Agriculture, Multidisciplinary
Weiliang Guan, Wenqian Nong, Xiaobo Wei, Renchi Chen, Zhihai Huang, Yuting Ding, Xiaoming Qin, Luyun Cai, Linchun Mao
Summary: This study investigated the effects of water-free transportation (WFT) on the glycolysis and lipolysis metabolism as well as the meat quality of shrimp. The results showed that WFT induced significant energy metabolism changes in shrimp flesh, which consequently affected the flesh quality. Compared to conventional water transportation (WT), WFT resulted in more pronounced physiological changes and a significant increase in drip loss of shrimp flesh.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Neuroimaging
Dapeng Sun, Baixue Jia, Xu Tong, Peter Kan, Xiaochuan Huo, Anxin Wang, Raynald, Gaoting Ma, Ning Ma, Feng Gao, Dapeng Mo, Ligang Song, Xuan Sun, Lian Liu, Yiming Deng, Xiaoqing Li, Bo Wang, Gang Luo, Yongjun Wang, Zeguang Ren, Zhongrong Miao
Summary: This study investigated the incidence, predictors, and clinical impact of parenchymal hemorrhage (PH) after endovascular treatment (EVT) in Chinese patients with acute ischemic stroke (AIS) caused by anterior circulation large vessel occlusion (LVO). The findings showed that low admission ASPECTS, high serum glucose, and elevated neutrophil-to-lymphocyte ratio (NLR) were independent predictors of PH, while underlying intracranial atherosclerotic stenosis (ICAS) and intracranial angioplasty/stenting were associated with a lower risk of PH. Additionally, patients with PH had worse functional outcomes.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Obstetrics & Gynecology
Xiang-Lan Liu, Li Ding, Xiao Lu, Yan-Jiao Hu, Xiao-Li Zhou, Dong-Liang Lin
Summary: A cervical yolk sac tumor in a 44-yr-old woman shares similarities with adenocarcinomas with enteroblastic differentiation (AEBDs) in the digestive system. The tumor exhibits a glandular-predominant growth pattern and is positive for p16, glypican-3 (GPC3), spalt-like transcription factor 4 (SALL4), CDX-2, and p53. TP53 mutation and HPV 35 infection were detected. This aggressive tumor should be recognized for its enteroblastic component in pathology reports.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
(2023)
Article
Nutrition & Dietetics
Qi Cui, Yang Xia, Yashu Liu, Yifei Sun, Kang Ye, Wenjie Li, Qijun Wu, Qing Chang, Yuhong Zhao
Summary: This study evaluated the reproducibility and validity of the Food Frequency Questionnaire (FFQ) for residents in northeast China. The findings demonstrated that the FFQ is reliable and valid for assessing the intake of most foods and nutrients.
BRITISH JOURNAL OF NUTRITION
(2023)
Correction
Obstetrics & Gynecology
Sadaf Pervaz, Amin Ullah, Enoch Appiah Adu-Gyamfi, Jones Lamptey, Sanjay Kumar Sah, Mei-Jiao Wang, Ying-Xiong Wang
REPRODUCTIVE SCIENCES
(2023)
Article
Public, Environmental & Occupational Health
Qing Chang, Qijun Wu, Yang Xia, Hehua Zhang, Shanyan Gao, Yixiao Zhang, Yuan Yuan, Jing Jiang, Hongbin Qiu, Jing Li, Chunming Lu, Chao Ji, Xin Xu, Donghui Huang, Huixu Dai, Zhiying Zhao, Hang Li, Xiaoying Li, Xiaosong Qin, Caigang Liu, Xiaoyu Ma, Xinrui Xu, Da Yao, Yuhong Zhao
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Fisheries
Qiuran Yu, Fenglu Han, Maoxian Huang, Xiaodan Wang, Jian G. Qin, Liqiao Chen, Erchao Li
Summary: This study found that different doses of myo-inositol can significantly affect the growth performance, body composition, serum metabolite composition, hepatopancreatic metabolite content, and digestive enzyme activity in juvenile Pacific white shrimp. It suggests that myo-inositol can promote shrimp growth by improving lipid utilization.
Article
Psychology, Multidisciplinary
Yefeng Chen, Yiwen Pan, Haohan Cui, Xiaolan Yang
Summary: This article proposes a possible mechanism that people may have underconfidence bias in information updating due to motivated reasoning, which generates the asymmetric pattern in contagion, different from the overconfident bias observed in the literature. The study designs an experiment to relate unethical behavior to social learning, where subjects decide whether to conduct unethical behavior publicly based on private information about penalty. The results confirm that people rely more on others' decisions than their own signal, suggesting the bias facilitates the contagion.
BEHAVIORAL SCIENCES
(2023)
Article
Nanoscience & Nanotechnology
Mengfei Li, QianQian Yang, Lili Fan, Xiaojie Dai, Zixi Kang, Rongming Wang, Daofeng Sun
Summary: Researchers have developed alternative electrocatalysts with high stability for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER). The electrocatalyst, composed of hollow CoOx nanoparticles embedded in carbon nanofibers, showed excellent long-term stability and promising performance in reversible Zn-air batteries. The remarkable electrocatalytic performance is attributed to the optimized adsorption of *OOH intermediate and reduced free energy of the potential-limiting step.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Letter
Biochemistry & Molecular Biology
Qiao-ling Ruan, Zhi-chao Wang, Cheng-jiang Wei, Wei Wang, Qing-luan Yang, Jing Wu, Yan-min Wan, Ling-ling Ge, Wen-hong Zhang, Qing-feng Li
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2023)
Article
Physiology
Xinwei Wang, Jiulong Song, Peng Xia, Qiang Lin, Anliang Chen, Kai Cheng, Fane Kong, Yi Shi, Xueping Li
Summary: High-intensity interval training (HIIT) is a physical therapy that can alleviate osteoarthritis (OA)-associated hyperalgesia. Cacna2d1, a subunit protein of calcium channel, plays a crucial role in nerve cell activity. However, the effect of HIIT on OA hyperalgesia and the involvement of Cacna2d1 remains unclear. In this study, OA rat models were established using monosodium iodoacetate (MIA) injection, and different groups were compared. Pain threshold, cartilage analysis, Cacna2d1 expression, and pain neurotransmitters were measured. The results demonstrated that HIIT could attenuate OA-associated hyperalgesia, possibly through the down-regulation of Cacna2d1 expression.
JOURNAL OF PHYSIOLOGICAL SCIENCES
(2023)
Article
Engineering, Biomedical
Ying Hu, Yan Liu, Siqi Zhang, Ting Zhang, Bin Dai, Bo Peng, Hongbo Yang, Yakang Dai
Summary: This study proposes a cross-space convolutional neural network (CS-CNN) for the classification of four-class motor imagery-electroencephalogram (MI-EEG), aiming to improve classification accuracy and robustness. The algorithm utilizes modified customized band common spatial patterns (CBCSP) and duplex mean-shift clustering (DMSClustering) to express specific rhythms and source distribution information in cross-space, and extracts multi-view features from time, frequency, and space domains to fuse the characteristics from two spaces and classify them using CNN. Experimental results show that the proposed algorithm achieves a classification accuracy of 96.05% (with real MRI information) and 94.79% (without MRI) in the private dataset. Moreover, in the BCI competition IV-2a, CS-CNN outperforms state-of-the-art algorithms with an accuracy improvement of 1.98% and a standard deviation reduction of 5.15%.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Immunology
Zhishuo Wang, Chenghua Yan, Qizhen Du, Yuying Huang, Xuezhen Li, Dan Zeng, Ruizhi Mao, Rama Krishna Gurram, Shipeng Cheng, Wangpeng Gu, Lin Zhu, Weiguo Fan, Liyan Ma, Zhiyang Ling, Ju Qiu, Dangsheng Li, Enmei Liu, Yaguang Zhang, Yiru Fang, Jinfang Zhu, Bing Sun
Summary: This study found a negative correlation between the neurotransmitter serotonin and the cytokines IL-5 and IL-13 produced by ILC2s, which are related to depression. Serotonin can alleviate lung inflammation by suppressing ILC2 activation. The serotonin receptor HTR2A is highly expressed on ILC2s and can be targeted with an agonist called DOI to inhibit ILC2 activation and reduce type 2 immune response. Targeting HTR2A on ST2(+) ILC2s could be a potential treatment strategy for type 2 lung inflammation.
CELLULAR & MOLECULAR IMMUNOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xi Lin, Lixing Dai, Qinqin Yang, Qizhi Yang, Hongjian He, Lingceng Ma, Jingjing Liu, Jingliang Cheng, Congbo Cai, Jianfeng Bao, Zhong Chen, Shuhui Cai, Jianhui Zhong
Summary: This study developed a real-time abdominal T-2 mapping method that does not require breath-holding or respiratory-gating. The single-shot multiple overlapping-echo detachment (MOLED) pulse sequence was used for free-breathing T-2 mapping of the abdomen. Deep learning was utilized to untangle the non-linear relationship between the MOLED signal and T-2 mapping. A synthetic data generation flow based on Bloch simulation, modality synthesis, and randomization was proposed to overcome the inadequacy of real-world training set.
EUROPEAN RADIOLOGY
(2023)
Article
Fisheries
Xiaochen Zhu, Penny Miller-Ezzy, Mark Gluis, Jianguang Qin, Youhong Tang, Yibing Liu, Yingying Zhao, Xiaoxu Li
Summary: This study investigated the effect of adding lipids and antioxidants on the survival rate of frozen mussel oocytes. The results showed that supplementing phospholipids or antioxidants in the base cryoprotectant agent significantly increased the survival rate of mussel larvae. Additionally, adding salmon lipid extract resulted in the highest survival rate and increased the number of mussel spat.
Article
Chemistry, Physical
Tengda Wang, Shaoying Dai, Jie Wang, Bin Liu, Meiwen Cao, Bo Guan, Yuchun Han, Yilin Wang
Summary: The large-scale use of detergents for oil-fouling removal in industry generates a significant amount of wastewater, leading to economic and environmental problems. This study presents a recyclable, efficient, and eco-friendly approach to remove oil-fouling by constructing a dynamic imine-based surfactant.
Article
Biochemistry & Molecular Biology
Fuqiang Ge, Qiaoling Yu, Jun Zhang, Yaoyao Han, Dongfa Zhu, Xi Xie
Summary: The E93 gene was identified and found to be widely distributed in adult tissues of the swimming crab. The expression levels of PtE93 mRNA in Y-organ and epidermis fluctuated during the molt cycle, suggesting its involvement in juvenile molting. Treatment with 20E induced PtE93 expression, while treatment with MF showed the opposite effect. The study also observed a negative correlation between PtE93 and ecdysteroid biosynthesis genes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Manuel Marrero, Oscar Monroig, Jose A. Perez, Monica B. Betancor, Ana Galindo, Ana Bolanos, N. Guadalupe Acosta, Covadonga Rodriguez
Summary: This study investigated the combined effects of partial dietary replacement of fish oil (FO) by vegetable oil (VO) and reduced ambient salinity on the fatty acid composition of C. labrosus juveniles. The results showed that C. labrosus is able to biosynthesise EPA and DHA from ALA, and low salinity conditions can upregulate the gene expression related to fatty acid metabolism. Fish reared on FO20 diet showed the highest amount of n-3 LC-PUFA in muscle.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Davide Degli Esposti, Aureline Lalouette, Karen Gaget, Louveline Lepeule, Zineb Chaabi, Maxime Lepretre, Anabelle Espeyte, Nicolas Delorme, Herve Queau, Laura Garnero, Federica Calevro, Arnaud Chaumot, Olivier Geffard
Summary: Metal pollution has significant effects on aquatic environments, and metallothioneins play important roles in maintaining metal homeostasis and detoxification. This study identified two metallothionein-coding transcripts in Gammarus fossarum and investigated their organ-specific expression patterns. The results showed that mt1 was more strongly induced after cadmium exposure, and mt1 was more highly induced in the caeca compared to the gills for any metal exposure. Additionally, mt2 was more inducible in the gills than in the caeca for cadmium and zinc exposure at the individual level.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Cuihong You, Shuangshuang Miao, Zhiyong Xie, Siyuan Lin, Shuqi Wang, Cuiying Chen, Li Lin, Yanhua Huang, Meng Zhou, Yewei Dong, Yuanyou Li, Ping Zhuang
Summary: The rabbitfish S. guttatus was found to have the capability for LC-PUFA biosynthesis, with the expression of related genes varying temporally and spatially during embryogenesis and being influenced by ambient salinity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Saydur Rahman, Mohammad Maruf Billah, Victor Rangel, Esmirna Cantu
Summary: Global warming has severe impacts on the reproductive fitness of marine invertebrates. In this study, the researchers used various techniques to investigate the effects of high temperatures on global DNA methylation, cellular apoptosis, and nitrative stress in the gonads of Atlantic sea urchins.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
E. S. Kladchenko, A. A. Tkachuk, M. S. Podolskaya, A. Yu. Andreyeva
Summary: This study investigated the osmotic stability and cellular responses of hemocytes in Mediterranean mussel and Pacific oyster. The results revealed that both species showed cellular volume changes and alterations in mitochondrial membrane potential upon hypoosmotic swelling. These findings provide insights into the cellular responses of bivalve mollusks to osmotic stress.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Yuya Ohhara, Chiemi Sagisaka, Kimiko Yamakawa-Kobayashi
Summary: This study investigated the biosynthetic capacity of n-3 PUFAs in the terrestrial invertebrate Sinella dubiosa, and found that it can metabolize oleic, linolenic, and arachidonic acids to produce EPA, suggesting that it may serve as an EPA source in soil ecosystems.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Correction
Biochemistry & Molecular Biology
N. Perales-Garcia, D. Tovar-Ramirez, M. G. Martinez-Morales, B. P. Ceballos-Vazquez, D. A. Corona-Rojas, M. A. Salcedo-Meza, A. Garrido-Mora, F. Vega-Villasante, H. Nolasco-Soria
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
N. Perales-Garcia, D. Tovar-Ramirez, M. G. Martinez-Morales, B. P. Ceballos-Vazquez, D. A. Corona-Rojas, M. A. Salcedo-Meza, A. Garrido-Mora, F. Vega-Villasante, H. Nolasco-Soria
Summary: This study provides the first report on the digestive tract pH of the pygmy octopus. The pH of the digestive tract regions was found to be lower than 7.0 and did not differ significantly between wild and captive octopuses. The digestive gland had the lowest pH values, but they were still above 5.0.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Carlos Espirito-Santo, Carmen Alburquerque, Francisco A. Guardiola, Rodrigo O. A. Ozorio, Leonardo J. Magnoni
Summary: Swimming has physiological effects on farmed fish, but the potential link between swimming and oxidative stress is still poorly understood. This study investigated the impact of different moderate swimming conditions on the antioxidant status of gilthead seabream, revealing that swimming modulated the activity of antioxidant enzymes in the liver and skeletal muscle. Adequate swimming conditions were found to minimize oxidative stress in gilthead seabream.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Yingxin Zhang, Chaobin Qin, Junli Wang, Liping Yang, Xiao Yan, Shaoyang Zhi, Guoxing Nie
Summary: The study focuses on the expression patterns of PFK genes in response to glucose, insulin, and glucagon stimuli in grass carp. The findings suggest that PFK family genes have different or even opposite expression patterns in various tissues, which may contribute to glucose intolerance in fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jianshuang Li, Likang Lyu, Haishen Wen, Yun Li, Xiaojie Wang, Yijia Yao, Xin Qi
Summary: This study investigated the transcriptional regulation of estrogen receptors (ESRs) on isotocin receptors (itrs) in guppies, and found that estrogen can regulate oxytocin receptor expression in ovoviviparous teleosts. The study also demonstrated that ESR1 represses itr2 promoter activity in an estrogen-dependent manner, while overexpression of ESR2a or ESR2b enhances itr2 promoter activity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Wan-Xin Li, Li-Ting Cai, Yan-Ping Huang, Yuan-Qing Huang, Shu-Hui Pan, Zhi-Long Liu, Charles Brighton Ndandala, Gang Shi, Si-Ping Deng, Hong-Juan Shi, Guang-Li Li, Dong-Neng Jiang
Summary: In this study, it was found that S. argus has two lep genes, with lepa highly expressed in the liver and lepb not detected in any tissue. lepa was found to play a role in regulating female reproduction in S. argus.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Li-Xiang Wu, Xiao-Ying Tan, Yi-Chuang Xu, Hua Zheng, Xiao-Lei Wei, Wu-Hong Lv, Zhi Luo
Summary: This study investigates the mechanisms underlying the activation of lipophagy in yellow catfish under high glucose-induced lipid deposition. The SIRT1-NRF2-TFEB pathway is proposed to mediate lipophagy activation, and lipophagy helps alleviate high glucose-induced lipid deposition. This study provides insights into the control of lipophagy in response to metabolic stress.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)