AML risk stratification models utilizing ELN-2017 guidelines and additional prognostic factors: a SWOG report

Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML

(2020) Courtney D. DiNardo et al.   BLOOD

Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients

(2019) Cheng-Hong Tsai et al.   EBioMedicine

Prognostic Value of Genetic Alterations in Elderly Patients with Acute Myeloid Leukemia: A Single Institution Experience

(2019) Maël Heiblig et al.   Cancers

Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia

(2019) Konstanze Döhner et al.   BLOOD

Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report

(2018) Era L. Pogosova-Agadjanyan et al.   BIOPRESERVATION AND BIOBANKING

Acute myeloid leukemia in very old patients

(2018) Vladimir Lj Lazarevic et al.   HAEMATOLOGICA

Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies

(2018) Ann-Kathrin Eisfeld et al.   LEUKEMIA

Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study

(2018) Yasuhiko Harada et al.   LEUKEMIA RESEARCH

Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report

(2018) Era L. Pogosova-Agadjanyan et al.   Biopreservation and Biobanking

Acute myeloid leukemia in very old patients

(2018) Vladimir Lj Lazarevic et al.   HAEMATOLOGICA

The stem cell-associated gene expression signature allows risk stratification in pediatric acute myeloid leukemia

(2018) Nicolas Duployez et al.   LEUKEMIA

Validation of the 2017 European LeukemiaNet classification for acute myeloid leukemia with NPM1 and FLT3 -internal tandem duplication genotypes

(2018) Prajwal C. Boddu et al.   CANCER

Next-generation sequencing-based genetic landscape and its clinical implications for Chinese acute myeloid leukemia patients

(2018) Xin-xin Cao et al.   Cancer Cell International

The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia

(2017) A-K Eisfeld et al.   LEUKEMIA

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

(2016) Hartmut Döhner et al.   BLOOD

Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia

(2016) K. H. Metzeler et al.   BLOOD

Cell cycle status in AML blast cells from peripheral blood, bone marrow aspirates and trephines and implications for biological studies and treatment

(2016) Rob S. Sellar et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clinical evaluation of panel testing by next-generation sequencing (NGS) for gene mutations in myeloid neoplasms

(2016) Chun Hang Au et al.   Diagnostic Pathology

Genetic alterations and their clinical implications in older patients with acute myeloid leukemia

(2016) C-H Tsai et al.   LEUKEMIA

A 17-gene stemness score for rapid determination of risk in acute leukaemia

(2016) Stanley W. K. Ng et al.   NATURE

COSMIC: somatic cancer genetics at high-resolution

(2016) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

(2016) Hsin-An Hou et al.   Oncotarget

High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia

(2016) Lin Fu et al.   Oncotarget

An integrative approach to predicting the functional effects of non-coding and coding sequence variation

(2015) Hashem A. Shihab et al.   BIOINFORMATICS

A 4-gene expression score associated with high levels ofWilms Tumor-1 (WT1)expression is an adverse prognostic factor in acute myeloid leukaemia

(2015) Ahmadreza Niavarani et al.   BRITISH JOURNAL OF HAEMATOLOGY

Prognostic Significance ofNPM1Mutations in the Absence ofFLT3–Internal Tandem Duplication in Older Patients With Acute Myeloid Leukemia: A SWOG and UK National Cancer Research Institute/Medical Research Council Report

(2015) Fabiana Ostronoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Correlation between peripheral blood and bone marrow regarding FLT3-ITD and NPM1 mutational status in patients with acute myeloid leukemia

(2014) W.-G. Tong et al.   HAEMATOLOGICA

A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia

(2013) S. H. Petersdorf et al.   BLOOD

A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia

(2013) K H Metzeler et al.   LEUKEMIA

A simple consensus approach improves somatic mutation prediction accuracy

(2013) David L Goode et al.   Genome Medicine

Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen

(2012) S. Ochsenreither et al.   BLOOD

Deregulated Expression of EVI1 Defines a Poor Prognostic Subset of MLL-Rearranged Acute Myeloid Leukemias: A Study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group

(2012) Stefan Gröschel et al.   JOURNAL OF CLINICAL ONCOLOGY

Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia

(2011) S. Schwind et al.   BLOOD

Risk stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and gene expression markers

(2011) V. Rockova et al.   BLOOD

WT1 overexpression at diagnosis may predict favorable outcome in patients withde novonon-M3 acute myeloid leukemia

(2011) Maurizio Miglino et al.   LEUKEMIA & LYMPHOMA

Stem cell gene expression programs influence clinical outcome in human leukemia

(2011) Kolja Eppert et al.   NATURE MEDICINE

BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

(2010) S. Schwind et al.   BLOOD

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia

(2009) Thomas R. Chauncey et al.   BRITISH JOURNAL OF HAEMATOLOGY

Favorable Prognostic Impact ofNPM1Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study

(2009) Heiko Becker et al.   JOURNAL OF CLINICAL ONCOLOGY

High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia

(2009) Gero Hütter et al.   Journal of Translational Medicine

What is the impact of hematopoietic cell transplantation (HCT) for older adults with acute myeloid leukemia (AML)?

(2008) Frederick R. Appelbaum   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study

(2008) C. Langer et al.   BLOOD

Identification of genes with abnormal expression changes in acute myeloid leukemia

(2007) Derek L. Stirewalt et al.   GENES CHROMOSOMES & CANCER