Article
Endocrinology & Metabolism
Yi Zhang, Min Tan, Boyu Liu, Manxia Zeng, You Zhou, Mengru Zhang, Yikai Wang, Jing Wu, Min Wang
Summary: This study aims to examine the association between bone mineral density (BMD) and hyperuricemia (HU) in obesity. The results showed a negative correlation between lumbar BMD and HU in obese individuals, particularly in men, while no significant relationship was found between hip BMD and HU.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Sarya Swed, Amro A. El-Sakka, Yasmeen Abouainain, Ka Yiu Lee, Bisher Sawaf, Mhd Kutaiba Albuni, Elias Battikh, Eman Mohammed sharif Ahmad, Nashaat Kamal Hamdy Elkalagi, Kirellos Said Abbas, Wael Hafez, Amine Rakab
Summary: Bone fractures are a global public health concern, but no comprehensive investigation on the use of low-dose aspirin to prevent fractures in the elderly has been conducted. This cross-sectional study found no significant association between the use of low-dose aspirin and fracture prevention in older adults. However, due to the higher incidence of fractures in the elderly, especially in women, it is important to implement more injury prevention initiatives and improve access to osteoporosis prevention and diagnosis to reduce the overall burden.
SCIENTIFIC REPORTS
(2023)
Article
Orthopedics
Min-zhe Xu, Ke Lu, Xu-feng Yang, Yao-wei Ye, Si-ming Xu, Qin Shi, Ya-qin Gong, Chong Li
Summary: This cross-sectional analysis revealed that serum uric acid levels were independently positively associated with bone mineral density in osteoporosis patients, especially in those with normal or low body weight. Serum uric acid levels may have a protective effect on bone mineral density at concentrations below 296μmol/L.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Health Care Sciences & Services
Soyeon Kang, Dongjin Kwon, Jiwoo Lee, Youn-Jee Chung, Mee-Ran Kim, Jeong Namkung, In Cheul Jeung
Summary: This study analyzed data from 328 postmenopausal women and found that serum uric acid level is not significantly associated with bone mineral density (BMD).
Article
Endocrinology & Metabolism
Gao-Xiang Wang, Ze-Bin Fang, Hui-Lin Li, De-Liang Liu, Shu-Fang Chu, Heng-Xia Zhao
Summary: This study found a saturation effect of obesity status on bone mineral density (BMD) in adolescents. Appropriate obesity status promotes bone mass development, while excessive obesity has a negative impact on BMD. The findings of this study are important for understanding adolescent bone health.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, Research & Experimental
Jiacheng Wang, Yi Zheng, Yawen Wang, Chengjun Zhang, Yanfeng Jiang, Chen Suo, Mei Cui, Tiejun Zhang, Xingdong Chen, Kelin Xu
Summary: This study investigated the association between lifetime body mass index (BMI) trajectories and bone loss. The results showed that rapid and excess weight gain during adulthood is associated with a higher risk of osteoporosis, but this association varies by skeletal sites. Maintaining stable overweight and obesity at an early stage may have potentially beneficial effects on bone health.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Orthopedics
Shuai Chen, Xiaohe Sun, Jie Jin, Guowei Zhou, Zhiwei Li
Summary: The monocyte-to-lymphocyte ratio (MLR), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) have been found to be associated with bone mineral density (BMD). Specifically, NLR is positively correlated with lumbar spine BMD, while PLR is negatively correlated with lumbar spine BMD.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Orthopedics
Jiazhong Ji, Yue Hou, Zhaoyang Li, Ying Zhou, Huaming Xue, Tao Wen, Tao Yang, Long Xue, Yihui Tu, Tong Ma
Summary: This study analyzed the association between physical activity and total spine bone mineral density (BMD) in postmenopausal women. The findings showed that engaging in ≥38MET-h of activity per week was associated with a lower risk of osteoporosis. Furthermore, the association between total spine BMD and moderate-to-vigorous PA was more significant among postmenopausal women aged < 65 years or individuals with normal BMI (< 25 kg/m(2)).
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Nutrition & Dietetics
Karina Robles-Rivera, Anna D. Argoty-Pantoja, Alberto Hidalgo-Bravo, Amado D. Quezada-Sanchez, Guadalupe Leon-Reyes, Yvonne N. Flores, Jorge Salmeron, Rafael Velazquez-Cruz, Berenice Rivera-Paredez
Summary: This study evaluated the association between uric acid (UA) and bone mineral density (BMD) in Mexican adults. The results showed that in females <45 years old, UA levels were positively associated with total hip BMD, but negatively associated with femoral neck and lumbar spine BMD in the longitudinal analysis. In males <45 years old, higher UA levels were associated with an increase in total hip and femoral neck BMD. In females >= 45 years old, there was a longitudinal association between UA and loss of BMD at different sites. No association was observed between UA levels and BMD in males >= 45 years old.
Article
Environmental Sciences
Yuchen Tang, Qiong Yi, Shenghong Wang, Yayi Xia, Bin Geng
Summary: The study found that high blood mercury levels may increase bone mineral density, especially in the femoral regions. There are differences in the relationship between blood mercury levels and bone mineral density among different populations, with a more significant association in non-Hispanic Whites and a negative correlation in non-Hispanic Blacks.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Immunology
Yuchen Tang, Bo Peng, Jinmin Liu, Zhongcheng Liu, Yayi Xia, Bin Geng
Summary: This study explores the association between systemic immune-inflammation index (SII) and bone mineral density (BMD) in postmenopausal women. The results suggest that higher SII is associated with lower BMD and increased risk of osteoporosis. Other inflammatory markers, such as neutrophil-to-lymphocyte ratio (NLR) and the product of platelet count and neutrophil count (PPN), are also negatively associated with BMD and positively associated with the risk of osteoporosis. These associations are more significant in postmenopausal women aged >=65 years or with normal BMI.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Endocrinology & Metabolism
Zih-Cen Lin, Jhu-Fong Wu, Chiung-Yun Chang, Kuan-Ming Lai, Hsin-Yi Yang
Summary: This study found no association between serum uric acid (sUA) levels and bone mineral density (BMD) at different skeletal sites in middle-aged and elderly men, but a positive association was only found in the normal weight group.
ARCHIVES OF OSTEOPOROSIS
(2022)
Article
Public, Environmental & Occupational Health
Yichen Liu, Yue Zeng, Jun Lu, Xiaoya Zhang, Zikai Zhang, Huijuan Li, Peipei Liu, Bin Ma, Yiqun Gu, Lige Song
Summary: This study aimed to evaluate the correlation between hemoglobin (Hb) and osteoporosis (OP) in the Chinese elderly population. The results showed that Hb level was positively correlated with bone mineral density (BMD) at the lumbar spine, femur neck, and total hip. After adjusting for confounding variables, the relationship remained significant. Additionally, lower Hb levels were associated with a higher risk of OP.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Nutrition & Dietetics
Yi Zheng, Jiacheng Wang, Yawen Wang, Kelin Xu, Xingdong Chen
Summary: This study aimed to investigate the association between three plant-based diet indexes and bone loss. The results showed that higher hPDI and PDI were associated with increased risk of bone loss, while higher uPDI was associated with increased risk of osteoporosis. Several sensitivity analyses were conducted to ensure the robustness of results. The study demonstrates the deleterious effects of a plant-based diet on bone health and emphasizes the importance of a balanced diet.
Article
Endocrinology & Metabolism
Cong Ma, Ronghui Yu, Junhong Li, Xiaoyan Wang, Jingjing Guo, Erya Xiao, Ping Liu
Summary: As the population ages, the incidence of osteoporosis among Parkinson's disease (PD) patients will continue to rise, causing a significant social burden due to falls and resulting disabilities. This study aimed to investigate the association between serum uric acid (UA) levels and bone mineral density (BMD) as well as the presence of osteoporosis in Chinese PD patients.
JOURNAL OF BONE AND MINERAL METABOLISM
(2023)