Article
Endocrinology & Metabolism
Leslie Farland, William J. Degnan, Holly R. Harris, Deirdre K. Tobias, Stacey A. Missmer
Summary: Overall, women with endometriosis were not at increased risk of type 2 diabetes. However, among subgroups at low risk for type 2 diabetes (i.e. non-obese women and women with no prior history of infertility or GDM), endometriosis was associated with a modest increased risk of type 2 diabetes.
Review
Endocrinology & Metabolism
Joline W. J. Beulens, Maria G. M. Pinho, Taymara C. Abreu, Nicole R. den Braver, Thao M. Lam, Anke Huss, Jelle Vlaanderen, Tabea Sonnenschein, Noreen Z. Siddiqui, Zhendong Yuan, Jules Kerckhoffs, Alexandra Zhernakova, Milla F. Brandao Gois, Roel C. H. Vermeulen
Summary: Type 2 diabetes is primarily influenced by environmental risks and modifiable factors such as lifestyle choices. The external exposome, including built, social, physico-chemical, and lifestyle/food environments, plays a significant role in the prevention of type 2 diabetes. Air pollution, residential noise, and area-level socioeconomic deprivation have been linked to an increased risk of type 2 diabetes, while neighborhood walkability and green space are associated with a reduced risk. The impact of food environment, social environment, and outdoor temperature on type 2 diabetes risk remains inconclusive and requires further investigation.
Article
Nutrition & Dietetics
Zhenzhen Wan, Tingting Geng, Rui Li, Xue Chen, Qi Lu, Xiaoyu Lin, Liangkai Chen, Yanjun Guo, Liegang Liu, Zhilei Shan, An Pan, JoAnn E. Manson, Gang Liu
Summary: This study investigated the association between vitamin D concentration and cardiovascular disease risk in type 2 diabetes patients. The results showed that higher serum vitamin D concentrations were significantly associated with lower risks of total CVD and ischemic heart disease (IHD). Maintaining adequate vitamin D status and avoiding deficiency may help prevent CVD complications in patients with type 2 diabetes.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Medicine, General & Internal
Ningbin Dai, Qianwen Shi, Yujie Hua, Yu Guo, Zheng Bian, Liming Li, Zhengming Chen, Ming Wu, Yan Lu
Summary: In the Chinese population, frequent snoring is independently associated with an increased risk of type 2 diabetes mellitus in both men and women. Additionally, there is an interaction effect between snoring and age on the risk of type 2 diabetes mellitus.
Article
Nutrition & Dietetics
Yan Huang, Feng Liu, A-Mei Chen, Peng-Fei Yang, Yang Peng, Jian-Ping Gong, Zhi Li, Guo-Chao Zhong
Summary: Adherence to a type 2 diabetes prevention diet is associated with a lower risk of pancreatic cancer in a US population. The study also suggests that the favorable association may be more pronounced in smokers. Further research is needed to confirm these findings.
CLINICAL NUTRITION
(2021)
Article
Geriatrics & Gerontology
Patricia Vaduva, Nasser Laouali, Guy Fagherazzi, Amandine Gelot, Fabrice Bonnet, Marina Kvaskoff
Summary: This study aimed to evaluate the association between endometriosis and incident type 2 diabetes. The results showed no significant association between endometriosis and the risk of type 2 diabetes, even after considering various factors.
Article
Environmental Sciences
Annie Doubleday, Catherine J. Knott, Marnie F. Hazlehurst, Alain G. Bertoni, Joel D. Kaufman, Anjum Hajat
Summary: The study found that neighborhood greenspace can reduce the risk of developing diabetes, suggesting that urban planning at the neighborhood level should support access to greenspaces and promote healthy behaviors to prevent diabetes. Further research is needed to understand how greenspaces influence diabetes risk and to develop better methods for assessing greenspace exposure and usage. Adjusting for neighborhood-level confounders should also be considered in future studies.
ENVIRONMENTAL HEALTH
(2022)
Article
Multidisciplinary Sciences
Abdoulaye Diawara, Djibril Mamadou Coulibaly, Talib Yusuf Abbas Hussain, Cheickna Cisse, Jian Li, Mamadou Wele, Mahamadou Diakite, Kassim Traore, Seydou O. Doumbia, Jeffrey G. Shaffer
Summary: The prevalence of T2D in the Niena community was 7.5%, with rates of 8.6% for females and 5.6% for males. Age, family history of diabetes, hypertension, waist circumference, and fetal macrosomia were significantly associated with T2D. 61.3% of T2D subjects were unaware of their diabetic status before the study.
SCIENTIFIC REPORTS
(2023)
Article
Ophthalmology
Ziwen Hui, Xiao Guo, Gabriella Bulloch, Meng Yuan, Kun Xiong, Shiran Zhang, Yifan Chen, Yuting Li, Huan Liao, Wenyong Huang, Zhuoting Zhu, Wei Wang
Summary: This study investigated the longitudinal changes in choroid and ganglion cell-inner plexiform layer (GCIPL) in type 2 diabetes mellitus (T2DM) patients and healthy populations over 2 years. The results showed that progressive thinning of choroid and GCIPL occurs in both healthy individuals and T2DM patients, with accelerated loss seen in NPDR patients.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Environmental Sciences
Pauline Rebouillat, Rodolphe Vidal, Jean-Pierre Cravedi, Bruno Taupier-Letage, Laurent Debrauwer, Laurence Gamet-Payrastre, Herve Guillou, Mathilde Touvier, Leopold K. Fezeu, Serge Hercberg, Denis Lairon, Julia Baudry, Emmanuelle Kesse-Guyot
Summary: The study revealed associations between dietary pesticide exposure and Type 2 Diabetes risk, with different effects depending on the types of pesticide mixture, and individuals with high dietary quality may have a lower risk.
ENVIRONMENTAL HEALTH
(2022)
Article
Sport Sciences
Mengyun Luo, Chenhao Yu, Borja Del Pozo Cruz, Liangkai Chen, Ding Ding
Summary: This study suggests that 30 min/day of moderate-intensity physical activity can help prevent type 2 diabetes (T2D), regardless of genetic risk. The findings show that engaging in moderate-to-vigorous-intensity physical activity, especially among individuals with high genetic risk, significantly reduces the incidence of T2D.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Article
Endocrinology & Metabolism
Hui-Xuan Wu, Tian-Yao Chu, Junaid Iqbal, Hong-Li Jiang, Long Li, Yan-Xuan Wu, Hou-De Zhou
Summary: The study compared the incidence risk of cardio-cerebrovascular events in maturity onset diabetes of the young (MODY), type 1 diabetes, and type 2 diabetes. The results showed that the risk of cardio-cerebrovascular events in MODY is between that of type 1 diabetes and type 2 diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Justin B. Echouffo-Tcheugui, Arnaud D. Kaze, Gregg C. Fonarow, Sam Dagogo-Jack
Summary: In individuals with type 2 diabetes, severe hypoglycemia is independently associated with a higher risk of incident heart failure.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Cardiac & Cardiovascular Systems
Araz Rawshani, Naveed Sattar, Darren K. McGuire, Oskar Wallstrom, Ulf Smith, Jan Boren, Goran Bergstrom, Elmir Omerovic, Annika Rosengren, Bjorn Eliasson, Deepak L. Bhatt, Aidin Rawshani
Summary: The study found that the incidence of valvular disease is increasing among patients with diabetes. In type 2 diabetes, systolic blood pressure, body mass index, and renal function were found to be associated with valvular lesions.
Review
Medicine, General & Internal
Ehtasham Ahmad, Soo Lim, Roberta Lamptey, David R. Webb, Melanie J. Davies
Summary: Type 2 diabetes accounts for nearly 90% of global diabetes cases, with an increasing number of affected individuals, particularly among young people. Early detection and proactive management are crucial for preventing complications and reducing mortality. Technology and precision medicine offer potential improvements to treatment outcomes but face significant barriers.
Article
Endocrinology & Metabolism
Sung Kyun Park, Xin Wang, Ning Ding, Carrie A. Karvonen-Gutierrez, Antonia M. Calafat, William H. Herman, Bhramar Mukherjee, Sioban D. Harlow
Summary: This study found a positive association between serum PFAS concentrations and incident diabetes risk, with specific PFAS such as n-PFOA and PFHxS potentially increasing the risk of diabetes. Reducing exposure to these chemicals may be crucial in lowering the risk of diabetes.
Article
Environmental Sciences
Seulbi Lee, Carrie Karvonen-Gutierrez, Bhramar Mukherjee, William H. H. Herman, Sung Kyun Park
Summary: Adipokines, which are secreted by adipose tissue, may be involved in obesity-related metabolic diseases. The impact of environmental phenols and parabens on racial disparities in metabolic disease burden is not well established and requires further investigation.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Min Jae Ju, Junghoon Kim, Sung Kyun Park, Dong Hyun Kim, Yoon-Hyeong Choi
Summary: The study revealed a significant association between ambient air pollution and age-related macular degeneration (AMD), with certain pollutants like NO2, CO, and PM10 showing positive correlations with early AMD prevalence, while O3 showed a negative correlation. Long-term exposure to ambient air pollution may contribute to the risk of AMD in middle-aged and older adults.
ENVIRONMENTAL RESEARCH
(2022)
Letter
Endocrinology & Metabolism
Sung Kyun Park, Xin Wang, Carrie A. Karvonen-Gutierrez
Article
Environmental Sciences
Xin Wang, Carrie A. Karvonen-Gutierrez, William H. Herman, Bhramar Mukherjee, Sung Kyun Park
Summary: Exposure to metals, especially arsenic, cobalt, and zinc, may contribute to the development of metabolic syndrome in midlife women. In addition, the presence of metal mixtures could also influence the risk of incident MetS.
ENVIRONMENTAL RESEARCH
(2022)
Article
Peripheral Vascular Disease
Ning Ding, Carrie A. Karvonen-Gutierrez, Bhramar Mukherjee, Antonia M. Calafat, Sioban D. Harlow, Sung Kyun Park
Summary: The study revealed positive associations between several PFAS and incident hypertension, suggesting that PFAS might be an underappreciated contributing factor to women's cardiovascular disease risk.
Article
Environmental Sciences
Mia Q. Peng, Carrie A. Karvonen-Gutierrez, William H. Herman, Bhramar Mukherjee, Sung Kyun Park
Summary: This study examined the association between phthalate exposure and body fat gain in midlife women. The results showed that higher levels of phthalate metabolites were associated with faster increases in body fat percentage, particularly in women who were normal/underweight at baseline. However, the estimates were attenuated in the sensitivity analyses, suggesting the need for further confirmation of the findings.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Xin Wang, Kelly M. Bakulski, Bhramar Mukherjee, Howard Hu, Sung Kyun Park
Summary: Chronic lead exposure has long-term health effects. Blood lead can be used to assess recent exposure, while bone lead can be used to assess chronic exposure. A machine learning approach called Super Learner was developed to predict bone lead concentrations by combining the predictions from multiple algorithms.
Article
Environmental Sciences
Xin Wang, Ning Ding, Sioban D. Harlow, John F. Randolph, Bhramar Mukherjee, Ellen B. Gold, Sung Kyun Park
Summary: Exposure to heavy metals may affect sex hormone levels in women. This study analyzed the association between urinary metal concentrations and serum levels of estradiol (E-2), follicle-stimulating hormone (FSH), testosterone, and sex hormone-binding globulin (SHBG) in a multi-ethnic group of women aged 45-56 years. The results showed that higher urinary metal concentrations were linked to lower E-2 levels for mercury and lead, higher FSH levels for lead, and higher SHBG levels for cadmium. However, no significant association was found between metals and testosterone levels.
ENVIRONMENTAL POLLUTION
(2023)
Article
Endocrinology & Metabolism
Ning Ding, Emily Zheutlin, Sioban D. Harlow, John F. Randolph Jr, Bhramar Mukherjee, Sung Kyun Park
Summary: This study found that ubiquitous endocrine-disrupting chemicals, phthalates, may affect ovarian folliculogenesis and steroidogenesis. In midlife women, associations were observed between urinary phthalate metabolites and hormones, as well as timing of natural menopause. The results suggest that reducing exposure to phthalates may be crucial in preventing reproductive effects.
JOURNAL OF THE ENDOCRINE SOCIETY
(2023)
Article
Environmental Sciences
Ning Ding, Carrie A. Karvonen-Gutierrez, Ami R. Zota, Bhramar Mukherjee, Sioban D. Harlow, Sung Kyun Park
Summary: This study found that environmental pollutants, including PFAS, may be a contributing factor to racial/ethnic disparities in hypertension. Black participants had a higher risk of developing hypertension, partly due to the effects of PFAS. Therefore, reducing PFAS exposure is an important public policy goal in order to reduce these disparities.
ENVIRONMENTAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Mia Q. Peng, Carrie A. Karvonen-Gutierrez, William H. Herman, Bhramar Mukherjee, Sung Kyun Park
Summary: This study examined the association between phthalate exposure and diabetes in midlife women and found that certain high-molecular-weight phthalate metabolites were potentially linked to a higher incidence of diabetes. However, the associations varied across racial/ethnic groups. Further investigation is needed to determine if phthalates cause diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Environmental Sciences
Habyeong Kang, Ning Ding, Carrie A. Karvonen-Gutierrez, Bhramar Mukherjee, Antonia M. Calafat, Sung Kyun Park
Summary: This study examined the associations between serum PFAS concentrations and longitudinal trajectories of blood lipids in midlife women undergoing the menopausal transition. The results showed that PFAS concentrations were positively associated with total and LDL cholesterol trajectories, and negatively associated with triglycerides trajectories.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)