Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression
出版年份 2020 全文链接
标题
Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression
作者
关键词
-
出版物
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-08-04
DOI
10.3389/fcell.2020.00566
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- High-fructose corn syrup enhances intestinal tumor growth in mice
- (2019) Marcus D. Goncalves et al. SCIENCE
- Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase
- (2019) Takahiro Hayasaki et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing
- (2019) Kostas C. Nikolaou et al. Cell Reports
- Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice
- (2018) Miguel A. Lanaspa et al. JOURNAL OF CLINICAL INVESTIGATION
- Fructose and sugar: A major mediator of non-alcoholic fatty liver disease
- (2018) Thomas Jensen et al. JOURNAL OF HEPATOLOGY
- Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice
- (2018) Tomohito Doke et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Peroxisomal disorders: Improved laboratory diagnosis, new defects and the complicated route to treatment
- (2018) Ronald J.A. Wanders MOLECULAR AND CELLULAR PROBES
- The peroxisome: an update on mysteries 2.0
- (2018) Markus Islinger et al. HISTOCHEMISTRY AND CELL BIOLOGY
- The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
- (2017) Maria Tiana et al. NUCLEIC ACIDS RESEARCH
- Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
- (2017) Thomas J. Park et al. SCIENCE
- Insights into the Hexose Liver Metabolism—Glucose versus Fructose
- (2017) et al. Nutrients
- HIF-1α contributes to hypoxia adaptation of the naked mole rat
- (2017) Bang Xiao et al. Oncotarget
- Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse
- (2017) Michael F. Wangler et al. PLoS Genetics
- Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites
- (2016) Jurgen R. Haanstra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Human disorders of peroxisome metabolism and biogenesis
- (2016) Hans R. Waterham et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential
- (2016) Wen-Lian Chen et al. CANCER CELL
- Effects of combined PPAR-γ and PPAR-α agonist therapy on fructose induced NASH in rats: Modulation of gene expression
- (2016) Enas A. Abd El-Haleim et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Dietary fructose-induced hepatocellular carcinoma development manifested in mice lacking apoptosis inhibitor of macrophage (AIM)
- (2016) Takayuki Ozawa et al. GENES TO CELLS
- A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation
- (2016) Xinjian Li et al. NATURE CELL BIOLOGY
- Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression
- (2016) Enas A Abd El-Haleim et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Proteotranscriptomic Analysis Reveals Stage Specific Changes in the Molecular Landscape of Clear-Cell Renal Cell Carcinoma
- (2016) Benjamin A. Neely et al. PLoS One
- REST is a hypoxia-responsive transcriptional repressor
- (2016) Miguel A. S. Cavadas et al. Scientific Reports
- Effect of dietary fructose on portal and systemic serum fructose levels in rats and in KHK−/− and GLUT5−/− mice
- (2015) Chirag Patel et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK
- (2015) Chirag Patel et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease
- (2015) Peter Mirtschink et al. NATURE
- Zellweger spectrum disorders: clinical overview and management approach
- (2015) Femke C. C. Klouwer et al. Orphanet Journal of Rare Diseases
- Advances in understanding the leukaemia microenvironment
- (2014) Yoko Tabe et al. BRITISH JOURNAL OF HAEMATOLOGY
- Hif-2α Promotes Degradation of Mammalian Peroxisomes by Selective Autophagy
- (2014) Katharina M. Walter et al. Cell Metabolism
- GLUT2, glucose sensing and glucose homeostasis
- (2014) Bernard Thorens DIABETOLOGIA
- Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy
- (2014) M. A. Lanaspa et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Sorbitol Dehydrogenase Overexpression and Other Aspects of Dysregulated Protein Expression in Human Precancerous Colorectal Neoplasms: A Quantitative Proteomics Study
- (2014) Anuli Uzozie et al. MOLECULAR & CELLULAR PROTEOMICS
- HIF-1α and HIF-2α are critically involved in hypoxia-induced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation
- (2014) Yanlong Liu et al. TOXICOLOGY LETTERS
- Normal Roles for Dietary Fructose in Carbohydrate Metabolism
- (2014) Maren Laughlin Nutrients
- Cholesterol biosynthesis and ER stress in peroxisome deficiency
- (2013) Phyllis L. Faust et al. BIOCHIMIE
- High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase
- (2013) Takuji Ishimoto et al. HEPATOLOGY
- The Proteome of Human Liver Peroxisomes: Identification of Five New Peroxisomal Constituents by a Label-Free Quantitative Proteomics Survey
- (2013) Thomas Gronemeyer et al. PLoS One
- Peroxisome deficiency-induced ER stress and SREBP-2 pathway activation in the liver of newborn PEX2 knock-out mice
- (2012) Werner J. Kovacs et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Fission and proliferation of peroxisomes
- (2012) M. Schrader et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mouse models for peroxisome biogenesis defects and β-oxidation enzyme deficiencies
- (2012) Myriam Baes et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- Uric Acid Induces Hepatic Steatosis by Generation of Mitochondrial Oxidative Stress
- (2012) Miguel A. Lanaspa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of fructose transporters in diseases linked to excessive fructose intake
- (2012) Veronique Douard et al. JOURNAL OF PHYSIOLOGY-LONDON
- Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
- (2012) Lei Liu et al. NATURE CELL BIOLOGY
- The spliceosome as a target of novel antitumour drugs
- (2012) Sophie Bonnal et al. NATURE REVIEWS DRUG DISCOVERY
- Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice
- (2012) T. Ishimoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Inventory of Peroxisomal Proteins and Pathways in Drosophila melanogaster
- (2012) Joseph E. Faust et al. TRAFFIC
- Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins
- (2012) Stephanie C. Huelga et al. Cell Reports
- Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease
- (2011) Marc Fransen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
- (2011) J. Schodel et al. BLOOD
- Carbohydrate Metabolism Is Perturbed in Peroxisome-deficient Hepatocytes Due to Mitochondrial Dysfunction, AMP-activated Protein Kinase (AMPK) Activation, and Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Suppression
- (2011) Annelies Peeters et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic and Functional Studies Implicate HIF1 as a 14q Kidney Cancer Suppressor Gene
- (2011) C. Shen et al. Cancer Discovery
- Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism
- (2010) Paul P. Van Veldhoven JOURNAL OF LIPID RESEARCH
- Both isoforms of ketohexokinase are dispensable for normal growth and development
- (2010) C. P. Diggle et al. PHYSIOLOGICAL GENOMICS
- Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
- (2009) David R. Mole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ketohexokinase: Expression and Localization of the Principal Fructose-metabolizing Enzyme
- (2009) Christine P. Diggle et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Hypoxia-Inducible Factor 2 Regulates Hepatic Lipid Metabolism
- (2009) E. B. Rankin et al. MOLECULAR AND CELLULAR BIOLOGY
- Regulation of the fructose transporter GLUT5 in health and disease
- (2008) Veronique Douard et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- HIF-1α and HIF-2α have divergent roles in colon cancer
- (2008) Takaaki Imamura et al. INTERNATIONAL JOURNAL OF CANCER
- Peroxisome Deficiency Causes a Complex Phenotype because of Hepatic SREBP/Insig Dysregulation Associated with Endoplasmic Reticulum Stress
- (2008) Werner J. Kovacs et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Slc2a5 (Glut5) Is Essential for the Absorption of Fructose in the Intestine and Generation of Fructose-induced Hypertension
- (2008) Sharon Barone et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started