Article
Chemistry, Analytical
Thawan G. Oliveira, Berlane G. Santos, Josue M. Goncalves, Lucio Angnes
Summary: This study developed a fast, precise, and reliable voltammetric method for quantifying indapamide, an orally active diuretic sulfonamide used for hypertensive treatment. The method showed linear responses and low detection limits in both tablet and synthetic urine samples. The flow injection analysis technique used in this method proved to be advantageous compared to classical chromatographic methods in terms of analysis speed. The study also compared the results obtained by voltammetry with those obtained by high performance liquid chromatography (HPLC), and showed good correlation.
Article
Chemistry, Applied
K. R. Venugopala Mounesh, K. R. Venugopala Reddy, Anup Pandith, Gaber E. Eldesoky, Bhari Mallanna Nagaraja
Summary: This work synthesized a novel nickel phthalocyanine compound and confirmed its structure using spectroscopic-microscopic methods and electrochemical analysis. The synthesized NiTBBTCAPc-MWCNTs showed enhanced electron transferring ability and electrocatalytic activity compared to bare GCE and other composite materials. The sensor exhibited fast response, good stability, and high selectivity towards nitrite. The modified electrode was successfully applied for quantitative detection of nitrite in drinking water and cabbage vegetable samples.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Energy & Fuels
Purusottam Reddy Bommireddy, Jayanth Babu Karnam, M. Chandra Sekhar, Si-Hyun Park
Summary: Recently, Prussian blue analogues (PBAs) have attracted considerable attention as efficient battery-type electrode materials for advanced hybrid supercapacitors. In this study, carbon nanotubes- (CNTs) and carbon nanofibers- (CNFs) hybridized NiHCC nanocomposites were successfully synthesized using a single-step hydrothermal process for investigating their battery-type electrochemical storage behavior in 3 M KOH. The synthesized electrodes exhibited battery-type charge storage mechanisms with excellent stability. Specifically, the NiHCC-CNT composite (NiHCC@CNT) electrode showed outstanding charge storage capacity (348 mAh g-1 at 1 Ag-1) due to its high electrochemically active surface area, low charge transfer resistance, and efficient utilization of redox centers for K+ ion storage. Furthermore, the hybrid capacitor constructed with NiHCC@CNT demonstrated excellent cycling stability over 5000 cycles, with a maximum energy density of 59 W h Kg- 1 at a power density of 1798 W Kg-1. This work highlights the potential of NiHCC@CNT composite as a cathode material for K+ ion supercapacitors.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Chemistry, Multidisciplinary
Jianwei Wang, Qian Ding, Caihui Bai, Feifei Wang, Shiguo Sun, Yongqian Xu, Hongjuan Li
Summary: The CNTs/CoNiFe-LDH hybrid material was successfully prepared using a one-step hydrothermal approach, which improved the conductivity and surface area of the electrode, leading to enhanced electrochemical performance. This material showed promising application in hybrid supercapacitor electrodes.
Article
Materials Science, Multidisciplinary
Linzhe Wang, Jian Qin, Zhimin Bai, Youchen Hao, Wenbin Li
Summary: A facile one-step hydrothermal route is used to synthesize core-branched FeOOH-CNTs composites. The optimized composites exhibit high specific capacitance and superior rate capability.
Article
Engineering, Chemical
Ngo Minh Phuoc, Nguyen Anh Thu Tran, Tran Minh Khoi, Hye Bin Jung, Wook Ahn, Euiyeon Jung, Chung-Yul Yoo, Hong Suk Kang, Younghyun Cho
Summary: Capacitive deionization (CDI) is a promising desalination technology known for its energy efficiency, cost effectiveness, and eco-friendly process. The use of flowable electrodes in CDI offers continuous desalination stream, however, limited salt removal efficiency remains a challenge in current systems.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Chemistry, Physical
Deepak Balram, Kuang-Yow Lian, Neethu Sebastian, N. Rasana
Summary: This paper details the detection of hepatotoxic antipyretic drug acetaminophen (APAP) at the nanomolar level using a novel nanocomposite with excellent electrocatalytic properties. The proposed APAP sensor demonstrated outstanding performance with a ultra-low detection limit of 1 nM and high sensitivity of 89.64 muA muM-1 cm-2. Experimental evaluation on real samples including APAP tablets, human urine, and human serum confirmed the practical feasibility of APAP detection.
APPLIED SURFACE SCIENCE
(2021)
Article
Materials Science, Ceramics
Sajjad Haider, Sahar Saad Shar, Imran Shakir, Philips O. Agboola
Summary: In this study, NiS and NiS/CNTs nanocomposites were synthesized using a hydrothermal technique. Structural characterization using XRD and FTIR, along with Scherer formula for crystallite size examination, confirmed the formation and purity of the samples. The improved bandgap energy of NiS/CNTs resulted in excellent photocatalytic degradation of methylene blue and enhanced antibacterial activity against various bacteria. The incorporation of carbon nanotubes in metal sulphide nanocomposites shows promising potential for wastewater treatment.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Aysu Arman, Sener Saglam, Aysem Uzer, Resat Apak
Summary: The study presented a sensitive detection method for nitroaromatic explosives using a GC/MWCNTs/PEI electrode coated with gold nanoparticles. The method successfully detected TNT, DNT, 2,4-DNP, PA, and tetryl in a linear range, with detection limits ranging from 15 μg L-1 to 135 μg L-1. This method was also validated against the reference LC-MS method for analyzing explosives in soil samples.
Review
Biochemical Research Methods
Nicolette Driscoll, Royce Dong, Flavia Vitale
Summary: Devices that record or modulate neural activity are crucial for clinical diagnostics, research, and consumer electronics. The development of stable interfaces between electronics and biological tissues is a significant challenge that requires material innovations. Nanocarbons and carbides offer specific advantages for neuroelectronics, enabling safe and precise interactions at various scales.
CURRENT OPINION IN BIOTECHNOLOGY
(2021)
Article
Chemistry, Analytical
Selen Ayaz, Aysem Uzer, Yusuf Dilgin, Resat Apak
Summary: A novel amperometric method was developed for total antioxidant capacity determination using a copper-neocuproine complex modified electrode in a flow injection system. The electrode exhibited good electrocatalytic activity towards polyphenolic compounds and showed a wide linear range and low detection limit. The method was successfully applied to measure antioxidant capacity in herbal teas, providing results comparable to spectrophotometric methods but with improved precision and sensitivity.
Article
Chemistry, Analytical
Ruihong Jia, Huiyun Bai, Yanbin He
Summary: An electrochemical sensor was developed for the determination of homocysteine. The sensor showed improved catalytic activity and sensitivity through self-assembly and modification techniques. Satisfactory results were obtained in the analysis of immunoglobulin G samples using the sensor.
ANALYTICAL LETTERS
(2023)
Article
Engineering, Electrical & Electronic
Jose Sanchez del Rio, Alvaro Ridruejo, Vanesa Martinez, Jose Luis Jimenez, Celia Ramos, Juan Jose Vilatela, Carlos Daniel Gonzalez
Summary: The quality of composites manufactured by resin infusion depends on operator expertise, which can be improved through careful monitoring of the process. In this study, macroscopic filaments made of multi-walled carbon nanotubes were integrated into different fabric materials to monitor fluid front advance during vacuum-assisted resin infusion. The electrical resistance change of the filaments was continuously recorded, but temperature and quality of electrical contacts were found to significantly affect the measurements.
SENSORS AND ACTUATORS A-PHYSICAL
(2023)
Article
Multidisciplinary Sciences
M. A. Deyab, Q. Mohsen
Summary: A new nanocomposite coating consisting of polyaniline conductive polymer, Cu-Porphyrin, and carbon nanotubes has been developed to protect the negative plate inside lead-acid batteries from hydrogen gas release and corrosion. Experimental results show that the coated Pb electrode has a high resistance to gas evolution and corrosion, leading to improved cycle performance of lead-acid batteries compared to uncoated electrodes.
SCIENTIFIC REPORTS
(2021)
Article
Nanoscience & Nanotechnology
Andjelika Bjelajac, Ileana Florea, Mihai Zamfir, Sandrine Tusseau Nenez, Costel Sorin Cojocaru
Summary: In this study, vertically aligned multiwall carbon nanotubes (CNTs) films were used as support for ZnO/ZnS photocatalytic active nanostructures. The CNTs were synthesized using a hot-filament chemical vapor deposition (HfCVD) method. Point defects in the CNTs outer walls were created using a low pressure nonthermal water vapors diffusive plasma, and Zn nanoparticles were subsequently electrodeposited onto the CNTs. The samples were annealed to obtain ZnO, ZnS, and a mix phase of ZnO/ZnS. The absorption of ZnO was enhanced by S doping and involvement of CNTs, and the ZnO1-xSx@CNTs heteronanostructure showed the highest photocatalytic activity for methyl blue dye degradation among the studied samples.
Article
Biotechnology & Applied Microbiology
Mehreen Ghufran, Mehran Ullah, Haider Ali Khan, Sabreen Ghufran, Muhammad Ayaz, Muhammad Siddiq, Syed Qamar Abbas, Syed Shams ul Hassan, Simona Bungau
Summary: During the SARS-CoV-2 outbreak, researchers extensively studied pharmacological strategies to decrease the viral load in severe patients. The M-pro protease, which is essential for viral replication, has been identified as a potential therapeutic target. To prevent further spread of the pandemic, scientists are actively searching for more efficient inhibitors against SARS-CoV-2.
BIOENGINEERING-BASEL
(2023)
Review
Cell Biology
Andrei-Flavius Radu, Simona Gabriela Bungau
Summary: Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder characterized by bone and cartilage damage in the synovium, resulting in joint impairment and increased mortality rate. Despite recent improvements in RA treatment, only a small fraction of patients achieve clinical remission without ongoing immunosuppressive drugs. Research on RA nano therapies has increased due to their potential advantages over traditional systemic treatments. Nanotherapeutic techniques, specifically drug delivery nano systems, offer new approaches to overcome the limitations of existing treatments by precisely delivering therapeutic drugs to affected sites.
AGEING RESEARCH REVIEWS
(2023)
Article
Medicine, Research & Experimental
Ruxandra-Cristina Marin, Simona Gabriela Bungau, Delia Mirela Tit, Paul Andrei Negru, Andrei-Flavius Radu, Radu Dumitru Moleriu
Summary: Approximately two-thirds of Romanian HIV patients were parenterally infected with the F subtype of HIV in early childhood. They are now facing immunological aging, with immunosuppression posing an additional challenge in developing effective and well-tolerated regimens. A retrospective study compared the immune recovery of 462 HIV-infected patients who received different treatment regimens, showing normal immune response but a significant difference between groups. The study also assessed the relationship between immune and virological responses to therapy, finding an association at the final visit.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Medicine, Research & Experimental
Aditi Sharma, Tapan Behl, Lalit Sharma, Om Prakash Shah, Shivam Yadav, Monika Sachdeva, Summya Rashid, Simona Gabriela Bungau, Cristiana Bustea
Summary: Recently, there has been increasing focus on the chronic neuro-inflammatory condition causing neuropathic pain, characterized by thermal hyperalgesia and tactile allodynia, which results from injury or infection in the nervous system. Angiogenesis, chemokines, and cytokines play important roles in the pathophysiology of neuropathic pain, contributing to inflammation and detrimental effects. Various mechanisms, including VEGF signaling, Tie-1 and Tie-2 receptor signaling, and erythropoietin pathway promoting axonal growth, have been identified as potential targets for therapeutic interventions in neuropathic pain associated with angiogenesis. Synthetic and herbal treatments targeting angiogenesis in neuropathic pain have also been explored.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Editorial Material
Biochemistry & Molecular Biology
Cosmin Mihai Vesa, Simona Gabriela Bungau
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Immunology
Rashita Makkar, Aayush Sehgal, Sukhbir Singh, Neelam Sharma, Ravi Rawat, Summya Rashid, Celia Vargas-De-La-Cruz, Shivam Yadav, Simona Gabriela Bungau, Tapan Behl
Summary: Rheumatoid arthritis is a chronic autoimmune disorder that mainly affects the joints and joint membrane, resulting in immune cell infiltration, synovium lining hyperplasia, pannus formation, and bone and cartilage destruction. It affects approximately 1% of the global population, with a higher prevalence in women. The aggressive phenotype of synovial fibroblasts in rheumatoid arthritis individuals leads to the upregulation of proto-oncogenes, adhesive compounds, inflammatory cytokines, and matrix-deteriorating enzymes. Current treatment options include non-steroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, and biologics targeting specific molecules. Understanding the pathogenesis and associated parameters would facilitate the development of advanced therapeutic approaches for managing this debilitating disease.
INFLAMMOPHARMACOLOGY
(2023)
Review
Health Care Sciences & Services
Nicoleta Anamaria Pascalau, Andrei-Flavius Radu, Delia Carmen Nistor Cseppento, Felicia Liana Andronie-Cioara, Anamaria Jurcau, Calin Mos, Alexa Florina Bungau, Simona Gabriela Bungau
Summary: Lymphangioleiomyomatosis (LAM) is a rare disease characterized by cystic lung destruction and respiratory failure. There may be a potential association between LAM and rheumatoid arthritis (RA) due to similar pathophysiological mechanisms involving dysregulated immunological function and inflammation. Further research is necessary to understand the connection between these two disorders and develop new therapeutic options.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Florentina Mihaela Pancescu, Abbas Abdul Kadhim Klaif Rikabi, Ovidiu Cristian Oprea, Alexandra Raluca Grosu, Aurelia Cristina Nechifor, Vlad-Alexandru Grosu, Szidonia-Katalin Tanczos, Florina Dumitru, Gheorghe Nechifor, Simona Gabriela Bungau
Summary: This paper presents the preparation and characterization of composite membranes based on chitosan and sulfonated ethylene-propylene-diene terpolymer, and evaluates their performance in the controlled release of melatonin. The prepared membranes can release different amounts of melatonin in dedicated environments.
Review
Biology
Cristiana Bustea, Alexa Florina Bungau, Delia Mirela Tit, Diana Carina Iovanovici, Mirela Marioara Toma, Simona Gabriela Bungau, Andrei-Flavius Radu, Tapan Behl, Adrian Cote, Elena Emilia Babes
Summary: Left ventricular non-compaction (LVNC) is a rare disease characterized by a two-layered ventricular wall, and controversies still exist regarding its classification. This review analyzes the diagnosis, treatment, and prognosis of LVNC, as well as the current knowledge regarding reverse remodeling. A case study is presented to illustrate the effectiveness of angiotensin receptor neprilysin inhibitor in LVNC treatment. LVNC is a heterogeneous cardiomyopathy, and while favorable outcomes are not common, some patients respond well to therapy.
Article
Biology
Cristiana Bustea, Delia Mirela Tit, Alexa Florina Bungau, Simona Gabriela Bungau, Vlad Alin Pantea, Elena Emilia Babes, Larisa Renata Pantea-Rosan
Summary: Recurrent hospitalizations after ACS are common, and identifying the risk factors is crucial for management. The study found that complete revascularization and higher left ventricular ejection fraction were independent predictors of reduced readmissions in the first year after an acute coronary event.
Article
Green & Sustainable Science & Technology
Manuel Alexandru Gitea, Daniela Gitea, Delia Mirela Tit, Simona Gabriela Bungau, Mihaela Alexandra Bogdan, Andrei-Flavius Radu, Francisc Vasile Dulf, Manuela Bianca Pasca
Summary: This study evaluated the physico-chemical and bioactive properties of grape seed oil (GSO) obtained from two grape varieties. The results showed that GSO has high antioxidant activity and is rich in polyunsaturated fatty acids and total polyphenols.
Article
Food Science & Technology
Ioana Mariana Has, Dan-Cristian Vodnar, Alexa Florina Bungau, Alexandra Georgiana Tarce, Delia Mirela Tit, Bernadette-Emoke Teleky
Summary: This study focuses on developing and evaluating oat- and millet-based snack bars enriched with freeze-dried elderberry powder (FDEBP), aiming to combine great taste with enhanced nutritional value, antioxidant properties, and prebiotic potential. The research encompassed a sensory evaluation, nutritional assessment, and rheological analysis of the snack bars. The results showed positive feedback from participants, with the best acceptance rating received by a bar enriched with 1% FDEBP. Rheological analysis demonstrated that the addition of FDEBP significantly impacted the structural strength of the bars.
Article
Infectious Diseases
Aroosa Zafar, Yusra Wasti, Muhammad Majid, Durdana Muntaqua, Simona Gabriela Bungau, Ihsan ul Haq
Summary: This study found that the combination of A. brevifolia and cefixime has the potential to inhibit antimicrobial resistance, effectively inhibiting the growth of resistant strains.
Article
Biology
Andrei-Flavius Radu, Paul Andrei Negru, Ada Radu, Alexandra Georgiana Tarce, Simona Gabriela Bungau, Mihaela Alexandra Bogdan, Delia Mirela Tit, Bogdan Uivaraseanu
Summary: This study investigated the potential use of phytoconstituents from Embelia ribes as treatment agents for rheumatoid arthritis (RA) using in silico methodologies. Several compounds were identified with high binding affinities to target proteins involved in RA, suggesting their potential for future therapeutic development.