Multifaceted p21 in carcinogenesis, stemness of tumor and tumor therapy

Integration of microbiology, molecular pathology, and epidemiology: a new paradigm to explore the pathogenesis of microbiome-driven neoplasms

(2019) Tsuyoshi Hamada et al.   JOURNAL OF PATHOLOGY

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

(2018) Chengdi Yang et al.   Molecular Cancer

Insights into Pathogenic Interactions Among Environment, Host, and Tumor at the Crossroads of Molecular Pathology and Epidemiology

(2018) Shuji Ogino et al.   Annual Review of Pathology-Mechanisms of Disease

Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation

(2017) Gitta M Seleznik et al.   GUT

p21: A Two-Faced Genome Guardian

(2017) Alexandros G. Georgakilas et al.   TRENDS IN MOLECULAR MEDICINE

Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis

(2016) Tsuyoshi Hamada et al.   JOURNAL OF GASTROENTEROLOGY

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Suppressor of cytokine signaling 1-dependent regulation of the expression and oncogenic functions of p21CIP1/WAF1 in the liver

(2016) M Yeganeh et al.   ONCOGENE

Targeted p21WAF1/CIP1 activation by miR-1236 inhibits cell proliferation and correlates with favorable survival in renal cell carcinoma

(2016) Chenghe Wang et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Downregulation of CDC27 inhibits the proliferation of colorectal cancer cells via the accumulation of p21Cip1/Waf1

(2016) L Qiu et al.   Cell Death & Disease

MiR-146b-5p overexpression attenuates stemness and radioresistance of glioma stem cells by targeting HuR/lincRNA-p21/β-catenin pathway

(2016) Wei Yang et al.   Oncotarget

Prognostic value of immunohistochemical markers in malignant thymic epithelial tumors

(2016) Priska Leisibach et al.   Journal of Thoracic Disease

MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathway

(2015) Yun-Li Chang et al.   Oncotarget

Abstract 1416: BMP 7 regulates dormancy and recurrence of prostate cancer stem cell in bone via P38/NDRG1/P21 signaling axis.

(2014) Fei Xing et al.   CANCER RESEARCH

Cdkn1A (p21) is required for quiescence, therapeutic resistance and clonal evolution of pre-leukemic stem cells

(2014) Cedric Tremblay et al.   EXPERIMENTAL HEMATOLOGY

Circular RNAs: splicing’s enigma variations

(2013) Matthias W Hentze et al.   EMBO JOURNAL

Group I p21-Activated Kinases (PAKs) Promote Tumor Cell Proliferation and Survival through the AKT1 and Raf-MAPK Pathways

(2012) C. W. Menges et al.   MOLECULAR CANCER RESEARCH

p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis

(2012) X Qian et al.   ONCOGENE

Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

(2012) Michael F Gallagher et al.   Journal of Ovarian Research

P21 (waf1/cip1) is required for non-small cell lung cancer sensitive to Gefitinib treatment

(2011) Yi-Fan Zhao et al.   BIOMEDICINE & PHARMACOTHERAPY

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

(2010) Nhi Huynh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Gambogic acid triggers DNA damage signaling that induces p53/p21Waf1/CIP1 activation through the ATR-Chk1 pathway

(2010) Jing-Jing Rong et al.   CANCER LETTERS

Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field

(2010) S. Ogino et al.   GUT

p21 promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker

(2010) Magdalena B Flak et al.   Molecular Cancer

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

(2010) M. K. Y. Siu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA interference-mediated knockdown of p21WAF1 enhances anti-tumor cell activity of oncolytic adenoviruses

(2009) M Shiina et al.   CANCER GENE THERAPY

p21CIP1attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo

(2009) Manran Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression of cell cycle regulators p21, p27 and p53 in metastasizing canine mammary adenocarcinomas versus normal mammary glands

(2009) R. Klopfleisch et al.   RESEARCH IN VETERINARY SCIENCE

p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

(2008) C. J. Braun et al.   CANCER RESEARCH