KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway

Transcription Factor KLF2 and Its Role in the Regulation of Inflammatory Processes

(2020) K. T. Turpaev   BIOCHEMISTRY-MOSCOW

What Role Does CFTR Play in Development, Differentiation, Regeneration and Cancer?

(2020) Margarida D. Amaral et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt- and Mutant CFTR

(2020) Ana P. Carapeto et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Functional genomics analysis of human colon organoids identifies key transcription factors.

(2020) Shiyi YIN et al.   PHYSIOLOGICAL GENOMICS

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

(2020) Przemysław Duda et al.   Cells

Concise Review: Regulation of Self-Renewal in Normal and Malignant Hematopoietic Stem Cells by Krüppel-Like Factor 4

(2019) Chun S. Park et al.   Stem Cells Translational Medicine

Defective CFTR promotes intestinal proliferation via inhibition of the hedgehog pathway during cystic fibrosis

(2019) Kaisheng Liu et al.   CANCER LETTERS

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum

(2019) João D. Santos et al.   Cells

Ezrin promotes pancreatic cancer cell proliferation and invasion through activating the Akt/mTOR pathway and inducing YAP translocation

(2019) Chunji Quan et al.   Cancer Management and Research

VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level

(2019) Guiying Cui et al.   Scientific Reports

MicroRNA-145 Antagonism Reverses TGF-β Inhibition of F508del CFTR Correction in Airway Epithelia

(2018) Farruk Lutful Kabir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A transcription factor network represses CFTR gene expression in airway epithelial cells

(2018) Michael J. Mutolo et al.   BIOCHEMICAL JOURNAL

A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic

(2018) Joana R. Lérias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Risk of gastrointestinal cancers in patients with cystic fibrosis: a systematic review and meta-analysis

(2018) Akihiro Yamada et al.   LANCET ONCOLOGY

Cystic fibrosis: a gastrointestinal cancer syndrome

(2018) Mordechai Slae et al.   LANCET ONCOLOGY

Recent Progress in CFTR Interactome Mapping and Its Importance for Cystic Fibrosis

(2018) Sang Hyun Lim et al.   Frontiers in Pharmacology

Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation

(2018) Sara Canato et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

KLF4, A Gene Regulating Prostate Stem Cell Homeostasis, Is a Barrier to Malignant Progression and Predictor of Good Prognosis in Prostate Cancer

(2018) Xiaozhong Xiong et al.   Cell Reports

Krüppel-like factor 4 (KLF4): What we currently know

(2017) Amr M. Ghaleb et al.   GENE

GeneHancer: genome-wide integration of enhancers and target genes in GeneCards

(2017) Simon Fishilevich et al.   Database-The Journal of Biological Databases and Curation

Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6

(2017) Sharon M. Rymut et al.   Scientific Reports

Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis

(2017) Jie Ting Zhang et al.   Scientific Reports

Targeting the PI3K/Akt/mTOR signalling pathway in Cystic Fibrosis

(2017) R. Reilly et al.   Scientific Reports

CFTR is a tumor suppressor gene in murine and human intestinal cancer

(2016) B L N Than et al.   ONCOGENE

Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis

(2016) Kaisheng Liu et al.   Oncotarget

PI3K and AKT: Unfaithful Partners in Cancer

(2015) Seraina Faes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increased NF-κB Activity and Decreased Wnt/β-Catenin Signaling Mediate Reduced Osteoblast Differentiation and Function in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mice

(2015) Carole Le Henaff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA Interference Screen to Identify Kinases That Suppress Rescue of ΔF508-CFTR

(2015) Agata M. Trzcińska-Daneluti et al.   MOLECULAR & CELLULAR PROTEOMICS

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis

(2015) Sandra Pankow et al.   NATURE

A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint

(2015) Cláudia A. Loureiro et al.   Science Signaling

A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint

(2015) Cláudia A. Loureiro et al.   Science Signaling

The transient expression ofKlf4andKlf5during adipogenesis depends on GSK3β activity

(2015) Carla Cervantes-Camacho et al.   Adipocyte

Transcription factors and miRNAs that regulate fetal to adult CFTR expression change are new targets for cystic fibrosis

(2014) V. Viart et al.   EUROPEAN RESPIRATORY JOURNAL

Cx26 regulates proliferation of repairing basal airway epithelial cells

(2014) S. Crespin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Vx-770 potentiates CFTR function by promoting decoupling between the gating cycle and ATP hydrolysis cycle

(2013) Kang-Yang Jih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies

(2013) Luka A Clarke et al.   RESPIRATORY RESEARCH

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Cancer Risk in Cystic Fibrosis: A 20-Year Nationwide Study From the United States

(2012) Patrick Maisonneuve et al.   JNCI-Journal of the National Cancer Institute

Use of Kinase Inhibitors to Correct ΔF508-CFTR Function

(2012) Agata M. Trzcińska-Daneluti et al.   MOLECULAR & CELLULAR PROTEOMICS

A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function

(2011) Jared M Bischof et al.   THORAX

The neuron-specific isoform of glycogen synthase kinase-3β is required for axon growth

(2010) Zafira Castaño et al.   JOURNAL OF NEUROCHEMISTRY

Mammalian Krüppel-Like Factors in Health and Diseases

(2010) Beth B. McConnell et al.   PHYSIOLOGICAL REVIEWS

Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells

(2009) Guadalupe Villarreal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Abrogation of Anti-Inflammatory Transcription Factor LKLF in Neutrophil-Dominated Airways

(2008) Milene T. Saavedra et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY