Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia

Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain

(2019) Roxana Aldea et al.   Frontiers in Aging Neuroscience

White matter capillaries in vascular and neurodegenerative dementias

(2019) Yoshiki Hase et al.   Acta Neuropathologica Communications

Iba-1-/CD68+ microglia are a prominent feature of age-associated deep subcortical white matter lesions

(2019) Rachel Waller et al.   PLoS One

Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain

(2019) Susanne J. van Veluw et al.   NEURON

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

(2018) Nazira J. Albargothy et al.   ACTA NEUROPATHOLOGICA

Chronic mild hypoxia promotes profound vascular remodeling in spinal cord blood vessels, preferentially in white matter, via an α5β1 integrin-mediated mechanism

(2018) Sebok K. Halder et al.   ANGIOGENESIS

Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology

(2018) Karen Horsburgh et al.   CLINICAL SCIENCE

Basement membrane and stroke

(2018) Yao Yao   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for Aβ Drainage

(2017) Alexandra K. Diem et al.   Frontiers in Neuroscience

Vascular basement membranes as pathways for the passage of fluid into and out of the brain

(2016) Alan W. J. Morris et al.   ACTA NEUROPATHOLOGICA

Vascular, glial, and lymphatic immune gateways of the central nervous system

(2016) Britta Engelhardt et al.   ACTA NEUROPATHOLOGICA

In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein

(2016) Farron L. McIntee et al.   Frontiers in Aging Neuroscience

Does the difference between PART and Alzheimer’s disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau?

(2015) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

Perturbations of the cerebrovascular matrisome: A convergent mechanism in small vessel disease of the brain?

(2015) Anne Joutel et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

MMP-2 Is Mainly Expressed in Arterioles and Contributes to Cerebral Vascular Remodeling Associated with TGF-β1 Signaling

(2015) Ye Hua et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

What are White Matter Hyperintensities Made of? Relevance to Vascular Cognitive Impairment

(2015) Joanna M. Wardlaw et al.   Journal of the American Heart Association

White Matter Changes in Dementia: Role of Impaired Drainage of Interstitial Fluid

(2014) Roy O. Weller et al.   BRAIN PATHOLOGY

Age-Associated White Matter Lesions: The MRC Cognitive Function and Ageing Study

(2014) Stephen B. Wharton et al.   BRAIN PATHOLOGY

Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain

(2013) Cheryl A. Hawkes et al.   AGING CELL

Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations

(2013) Cheryl A. Hawkes et al.   EXPERIMENTAL NEUROLOGY

Assessing White Matter Ischemic Damage in Dementia Patients by Measurement of Myelin Proteins

(2013) Rachel Barker et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Review: Cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy

(2013) R. O. Carare et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

(2011) Yoko Okamoto et al.   ACTA NEUROPATHOLOGICA

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

(2011) Cheryl A. Hawkes et al.   ACTA NEUROPATHOLOGICA

Vascular pathology in the aged human brain

(2010) Lea Tenenholz Grinberg et al.   ACTA NEUROPATHOLOGICA

Review: Sporadic cerebral amyloid angiopathy

(2010) J. Attems et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Lymphatic drainage of the brain and the pathophysiology of neurological disease

(2008) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA