Role of Monocytes/Macrophages in Covid-19 Pathogenesis: Implications for Therapy

Coagulation Disorders in Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome

(2020) Sandrine Valade et al.   CRITICAL CARE CLINICS

Clinical features and diagnosis of new malignancy in patients with acute pulmonary embolism and without a history of cancer

(2020) Yen-Chung Lin et al.   Journal of the Chinese Medical Association

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

COVID-19: combining antiviral and anti-inflammatory treatments

(2020) Justin Stebbing et al.   LANCET INFECTIOUS DISEASES

Is COVID-19 receiving ADE from other coronaviruses?

(2020) Jason A. Tetro   MICROBES AND INFECTION

The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China

(2020) Wen Zhang et al.   CLINICAL IMMUNOLOGY

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

(2020) Chi Zhang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Tocilizumab treatment in COVID-19: A single center experience

(2020) Pan Luo et al.   JOURNAL OF MEDICAL VIROLOGY

Angiotensin‐converting enzyme‐2 ( ACE2 ), SARS‐CoV ‐2 and pathophysiology of coronavirus disease 2019 ( COVID ‐19)

(2020) Arno R. Bourgonje et al.   JOURNAL OF PATHOLOGY

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

ST-Segment Elevation in Patients with Covid-19 — A Case Series

(2020) Sripal Bangalore et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease

(2020) Dennis McGonagle et al.   AUTOIMMUNITY REVIEWS

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

(2020) Elizabeth Whittaker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The pathogenesis and treatment of the `Cytokine Storm' in COVID-19

(2020) Qing Ye et al.   JOURNAL OF INFECTION

Autoimmune and inflammatory diseases following COVID-19

(2020) Caroline Galeotti et al.   Nature Reviews Rheumatology

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update

(2019) Noushin Lotfi et al.   Frontiers in Immunology

Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms

(2019) Maria K. Smatti et al.   Viruses-Basel

Perturbation of the Monocyte Compartment in Human Obesity

(2019) Kathleen Friedrich et al.   Frontiers in Immunology

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

(2018) Margherita Norelli et al.   NATURE MEDICINE

CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade

(2018) Theodoros Giavridis et al.   NATURE MEDICINE

Cytokine release syndrome

(2018) Alexander Shimabukuro-Vornhagen et al.   Journal for ImmunoTherapy of Cancer

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

(2018) Rosalie M. Sterner et al.   BLOOD

Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System

(2017) Sabine Spath et al.   IMMUNITY

Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody

(2017) Katherine V. Houser et al.   PLoS Pathogens

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

Immunotherapeutic implications of IL-6 blockade for cytokine storm

(2016) Toshio Tanaka et al.   Immunotherapy

Human monocyte subsets exhibit divergent angiotensin I-converting activity

(2015) M. Rutkowska-Zapała et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Middle East respiratory syndrome

(2015) Alimuddin Zumla et al.   LANCET

Usage of venous thromboembolism prophylaxis at a tertiary care hospital in Aseer region of Saudi Arabia

(2015) Ali AlBshabshe et al.   SAUDI MEDICAL JOURNAL

Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation

(2015) Sardar Sindhu et al.   PLoS One

Current concepts in the diagnosis and management of cytokine release syndrome

(2014) D. W. Lee et al.   BLOOD

Immune-Induced Fever Is Mediated by IL-6 Receptors on Brain Endothelial Cells Coupled to STAT3-Dependent Induction of Brain Endothelial Prostaglandin Synthesis

(2014) A. Eskilsson et al.   JOURNAL OF NEUROSCIENCE

Outcome of pediatric patients with lymphoma following stem cell transplant: a single institution report

(2014) Hassan Sumaili et al.   LEUKEMIA & LYMPHOMA

Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus

(2014) Ming Yip et al.   Virology Journal

Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment

(2013) S. K. P. Lau et al.   JOURNAL OF GENERAL VIROLOGY

Active Replication of Middle East Respiratory Syndrome Coronavirus and Aberrant Induction of Inflammatory Cytokines and Chemokines in Human Macrophages: Implications for Pathogenesis

(2013) Jie Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

(2012) Chien-Te Tseng et al.   PLoS One

SARS-CoV Regulates Immune Function-Related Gene Expression in Human Monocytic Cells

(2012) Wanchung Hu et al.   VIRAL IMMUNOLOGY

Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor- , in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study

(2011) G. R. Burmester et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent Fc R Pathway

(2011) M. Jaume et al.   JOURNAL OF VIROLOGY

Monocytes in Acute Coronary Syndromes

(2009) Eduard Shantsila et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Severe Acute Respiratory Syndrome (SARS) Coronavirus-Induced Lung Epithelial Cytokines Exacerbate SARS Pathogenesis by Modulating Intrinsic Functions of Monocyte-Derived Macrophages and Dendritic Cells

(2008) T. Yoshikawa et al.   JOURNAL OF VIROLOGY

Role of Dendritic Cells in Antibody-Dependent Enhancement of Dengue Virus Infection

(2008) K. Boonnak et al.   JOURNAL OF VIROLOGY