Metformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells

Tai Chi for type 2 diabetes mellitus

(2020) Xixi Chen et al.   MEDICINE

Autophagy and autophagy-related proteins in cancer

(2020) Xiaohua Li et al.   Molecular Cancer

Diabetes, an independent poor prognostic factor of non-B non-C hepatocellular carcinoma, correlates with dihydropyrimidinase-like 3 promoter methylation

(2020) Satoko Umetsu et al.   Scientific Reports

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation

(2019) Lu Gao et al.   CANCER LETTERS

SOX18 Affects Cell Viability, Migration, Invasiveness, and Apoptosis in Hepatocellular Carcinoma (HCC) Cells by Participating in Epithelial-to-Mesenchymal Transition (EMT) Progression and Adenosine Monophosphate Activated Protein Kinase (AMPK)/Mammalian Target of Rapamycin (mTOR)

(2019) Yanni Sun et al.   MEDICAL SCIENCE MONITOR

Pioglitazone protects tubular cells against hypoxia/reoxygenation injury through enhancing autophagy via AMPK-mTOR signaling pathway

(2019) Xiaoqing Xi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Type 2 Diabetes Prevention Diet and Hepatocellular Carcinoma Risk in US Men and Women

(2019) Xiao Luo et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin

(2019) Simon R. Lord et al.   BRITISH JOURNAL OF CANCER

Metformin in colorectal cancer: molecular mechanism, preclinical and clinical aspects

(2019) Muhamad Noor Alfarizal Kamarudin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Expression and role of autophagy related protein p62 and LC3 in the retina in a rat model of acute ocular hypertension

(2019) Yu-Yu Wu   International Journal of Ophthalmology

SP1 reduces autophagic flux through activating p62 in gastric cancer cells

(2018) Xiao‑Wu Xu et al.   Molecular Medicine Reports

Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway

(2018) Hongjun Fan et al.   CARCINOGENESIS

Targeting AMPK, mTOR and β-Catenin by Combined Metformin and Aspirin Therapy in HCC: An Appraisal in Egyptian HCC Patients

(2017) Doaa Ali Abdelmonsif et al.   Molecular Diagnosis & Therapy

Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway

(2017) Hsin-Hwa Tsai et al.   Oncotarget

Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway

(2016) Sunbin Ling et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Metformin Promotes Apoptosis but Suppresses Autophagy in Glucose-Deprived H4IIE Hepatocellular Carcinoma Cells

(2015) Deok-Bae Park   Diabetes & Metabolism Journal

Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy

(2014) Teng Jiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metformin Plays a Dual Role in MIN6 Pancreatic β Cell Function through AMPK-dependent Autophagy

(2014) Yingling Jiang et al.   International Journal of Biological Sciences

Blocking Autophagic Flux Enhances Matrine-Induced Apoptosis in Human Hepatoma Cells

(2013) Li Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dissociation of Bcl-2-Beclin1 Complex by Activated AMPK Enhances Cardiac Autophagy and Protects Against Cardiomyocyte Apoptosis in Diabetes

(2012) C. He et al.   DIABETES

Metformin and reduced risk of hepatocellular carcinoma in diabetic patients: a meta-analysis

(2012) Hui Zhang et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY