Glycopyrrolate and formoterol fumarate for the treatment of COPD

Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD

(2020) Klaus F. Rabe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Benralizumab for the Prevention of COPD Exacerbations

(2019) Gerard J. Criner et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized, Double-Blind, Double-Dummy Study of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Relative to Umeclidinium/Vilanterol Dry Powder Inhaler in COPD

(2019) François Maltais et al.   ADVANCES IN THERAPY

A phase III study of triple therapy with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler 320/18/9.6 μg and 160/18/9.6 μg using co-suspension delivery technology in moderate-to-very severe COPD: The ETHOS study protocol

(2019) Klaus F. Rabe et al.   RESPIRATORY MEDICINE

Gamma scintigraphic pulmonary deposition study of glycopyrronium/formoterol metered dose inhaler formulated using co-suspension delivery technology

(2018) Glyn Taylor et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study

(2018) Chen Wang et al.   LANCET

Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial

(2018) Alberto Papi et al.   LANCET

Cardiovascular safety profile of a fixed-dose combination of glycopyrrolate and formoterol fumarate delivered via metered dose inhaler using co-suspension delivery technology

(2018) Gary T. Ferguson et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Randomized study of the effects of Aerochamber Plus ® Flow-Vu ® on the efficacy, pharmacokinetics and safety of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler in patients with chronic obstructive pulmonary disease

(2018) Faisal Fakih et al.   RESPIRATORY MEDICINE

Pharmacokinetics of glycopyrronium/formoterol fumarate dihydrate delivered via metered dose inhaler using co-suspension delivery technology in patients with moderate-to-very severe COPD

(2018) Gary T Ferguson et al.   International Journal of Chronic Obstructive Pulmonary Disease

Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD

(2018) Colin Reisner et al.   International Journal of Chronic Obstructive Pulmonary Disease

Pharmacokinetics and safety of a single dose of the novel LAMA/LABA fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler, formulated using co-suspension delivery technology, in Japanese healthy subjects

(2018) Colin Reisner et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

A randomized study using functional respiratory imaging to characterize bronchodilator effects of glycopyrrolate/formoterol fumarate delivered by a metered dose inhaler using co-suspension delivery technology in patients with COPD

(2018) Wilfried De Backer et al.   International Journal of Chronic Obstructive Pulmonary Disease

Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

(2018) Brian J Lipworth et al.   International Journal of Chronic Obstructive Pulmonary Disease

Triple therapy with budesonide/glycopyrrolate/formoterol fumarate with co-suspension delivery technology versus dual therapies in chronic obstructive pulmonary disease (KRONOS): a double-blind, parallel-group, multicentre, phase 3 randomised controlled trial

(2018) Gary T Ferguson et al.   Lancet Respiratory Medicine

Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial

(2017) Jørgen Vestbo et al.   LANCET

Long-term safety and efficacy of glycopyrrolate/formoterol metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with chronic obstructive pulmonary disease

(2017) Nicola A. Hanania et al.   RESPIRATORY MEDICINE

Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Joan B Soriano et al.   Lancet Respiratory Medicine

A Two-Period Open-Label, Single-Dose Crossover Study in Healthy Volunteers to Evaluate the Drug–Drug Interaction Between Cimetidine and Inhaled Extrafine CHF 5993

(2016) Fabrizia Mariotti et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

A multicenter, randomized, double-blind dose-ranging study of glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler compared to the monocomponents and open-label tiotropium dry powder inhaler in patients with moderate-to-severe COPD

(2016) Donald P. Tashkin et al.   RESPIRATORY MEDICINE

Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial

(2016) Henrik Watz et al.   Lancet Respiratory Medicine

Imaging in Aerosol Medicine

(2015) T. E. Corcoran   Respiratory Care

Withdrawal of Inhaled Glucocorticoids and Exacerbations of COPD

(2014) Helgo Magnussen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of cimetidine, a model drug for inhibition of the organic cation transport (OCT2/MATE1) in the kidney, on the pharmacokinetics of glycopyrronium

(2013) Swati Dumitras et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS